References
- Teorell, T. : Kinetics of distribution of substances administered to the body I : The extravascular modes of administration. Arch. Int. Pharmacodyn. Ther. 57, 205 (1937).
- Malcolm, R., Carl, P. and Geoffrey. T. : Physiologically-based pharmacokinetics in drug development and regulatory science. Annu. Rev. Pharmacol. Toxicol. 51, 45 (2011). https://doi.org/10.1146/annurev-pharmtox-010510-100540
- Hannah, M. J., Maurice, D., Kuresh, Y., James, R. G., Neil, J. A., Tanya, L. H., Ian, K. G., Raj, L., Peter, J. B., Barry, C. J. and Iain, B. G. : Application of PBPK modelling in drug discovery and development at Pfizer. Xenobiotica. 42, 94 (2012). https://doi.org/10.3109/00498254.2011.627477
- Jones, H., Chen, Y., Gibson, C., Heimbach, T., Parrott, N., Peters, S., Snoeys, J., Upreti, V., Zheng, M. and Hall, S. : Physiologically based pharmacokinetic modelling in drug discovery and development : A pharmaceutical industry perspective. Clin. Pharmacol. Ther. 97, 3 (2015).
- Jones, H. and Rowland, Y. K. : Basic concepts in physiologically based pharmacokinetic modeling in drug discovery and development. CPT Pharmacometrics Syst. Pharmacol. 2, e63 (2013). https://doi.org/10.1038/psp.2013.41
- 윤휘열, 백인환, 서정원, 배경진, 이만형, 강원구, 권광일 : 모델 기반학적 신약개발에서 약동/약력학 모델링 및 시뮬레이션의 역할. Korean J. Clin. Pharm. 18, 84 (2008).
- 이상민, 최보윤, 윤휘열, 전다혜, 김명규, 하지혜, 김영훈, 지은희, 강원구, 한나영 : 효율적인 의약품 평가를 위한 약물계량학 분석법 도입의 전략 방안. Korean J. Clin. Pharm. 21, 339 (2011).
- GastroPlus http://www.simulations?plus.com/Products.aspx?grpID=3&cID=16&pID=11 (Accessed2013).
- Rodgers, T. and Rowland, M. : Physiologically based pharmacokinetic modelling 2 : predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions. J. Pharm. Sci. 95, 1238 (2006). https://doi.org/10.1002/jps.20502
- Khalil, F. and Laer, S. : Physiologically based pharmacokinetic models in the prediction of oral drug exposure over the entire pediatric age range-Sotalol as a model drug. AAPS J. 16, 226 (2014). https://doi.org/10.1208/s12248-013-9555-6
- Siladitya, R. C., Viera, L. and Walter, S. W. : Modeling disposition of sotalol following Intravenous and oral administration in healthy adult subjects. Abstract #T3075, AAPS Annual Meeting and Exposition. October 23-27 Washington Convention Center, Washington, D.C. (2011).
- Poirier, J. M., Jaillon, P., Lecocq, B., Lecocq, V., Ferry, A. and Cheymol, G. : The pharmacokinetics of d-sotalol and d, lsotalol in healthy volunteers. Eur. J. Clin. Pharmacol. 38, 579 (1990). https://doi.org/10.1007/BF00278585
- James, J. H. : Clinical pharmacokinetics of sotalol. Am. J. Cardiol. 72, 19a (1993). https://doi.org/10.1016/0002-9149(93)90021-4
- Deneer, V. H., Lie, A. H. L., Kingma, J. H., Proost, J. H., Kelder, J. C. and Brouwers, J. R. : Absorption kinetics of oral sotalol combined with cisapride and sublingual sotalol in healthy subjects. Br. J. Clin. Pharmacol. 45, 485(1998).
- Tjandramaga, T. B., Verbeeck, R., Thomas, J., Verbesselt, R., Verberckmoes, R. and Schepper, P. J. : The effect of end?stage renal failure and haemodialysis on the elimination kinetics of sotalol. Br. J. Clin. Pharmacol. 3, 259 (1976). https://doi.org/10.1111/j.1365-2125.1976.tb00601.x
- Laer, S., Elshoff, J. P., Meibohm, B., Weil, J., Mir, T. S., Zhang, W. and Hulpke, W. M. : Development of a safe and effective pediatric dosing regimen for sotalol based on population pharmacokinetics and pharmacodynamics in children with supraventricular tachycardia. J. Am. Coll. Cardiol. 46, 1322 (2005). https://doi.org/10.1016/j.jacc.2005.06.061
- Egan, J. M. and Abernethy, D. R. : Lorazepam analysis using liquid chromatography : improved sensitivity for single-dose pharmacokinetic studies. J. Chromatogr. 380, 196 (1986). https://doi.org/10.1016/S0378-4347(00)83643-9
- Greenblatt, D. J., Comer, W. H., Elliott, H. W., Shader, R. I., Knowles, J. A. and Ruelius, H. W. : Clinical pharmacokinetics of lorazepam. III. Intravenous injection. Preliminary results. J. Clin. Pharmacol. 17, 490 (1977). https://doi.org/10.1002/j.1552-4604.1977.tb05641.x
- Muchohi, S. N., Obiero, K., Newton, C. R., Ogutu, B. R., Edwards, G. and Kokwaro, G. O. : Pharmacokinetics and clinical efficacy of lorazepam in children with severe malaria and convulsions. Br. J. Clin. Pharmacol. 65, 12 (2008). https://doi.org/10.1111/j.1365-2125.2007.02966.x
- Chamberlain, J. M., Capparelli, E. V., Brown, K. M., Vance, C. W., Lillis, K., Mahajan, P., Lichenstein, R., Stanley, R. M., Davis, C. O., Gordon, S., Baren, J. M. and van den Anker, J. N. : Pharmacokinetics of intravenous lorazepam in pediatric patients with and without status epilepticus. J. Pediatr. 160, 667 (2012). https://doi.org/10.1016/j.jpeds.2011.09.048
- Maharaj, A. R., Barrett, J. S. and Edginton, A. N. : A workflow example of PBPK modeling to support pediatric research and development : case study with lorazepam. AAPS J. 15, 455 (2013). https://doi.org/10.1208/s12248-013-9451-0
-
Yang, Y., Faustino, P. J., Volpe, D. A., Ellison, C. D., Lyon, R. C. and Yu, L. X. : Biopharmaceutics classification of selected
${\beta}$ - blockers : Solubility and permeability class membership. Mol. Pharm. 4, 608 (2007). https://doi.org/10.1021/mp070028i - Dahan, A., Miller, J. M., Hilfinger, J. M., Yamashita, S., Yu, L. X., Lennernas, H. and Amidon, G. L. : High-permeability criterion for BCS classification: segmental/pH dependent permeability considerations. Mol. Pharm. 7, 1827 (2010). https://doi.org/10.1021/mp100175a
- Andrea, N. Edginton and Nikoletta, Fotaki : Oral drug absorption in pediatric populations, Oral drug absorption : prediction and assessment. 2nd ed. New York : Informa healthcare, 108 (2010).
- Fernandez, E., Perez, R., Hernandez, A., Tejada, P., Arteta, M. and Ramos, J. T. : Factors and mechanisms for pharmacokinetic differences between pediatric population and adults. Pharmaceutics. 3, 53 (2011). https://doi.org/10.3390/pharmaceutics3010053
- Zhao, P., Rowland, M. and Huang, S. M. : Best practice in the use of physiologically based pharmacokinetic modeling and simulation to address clinical pharmacology regulatory questions. Clin. Pharmacol. Ther. 92, 17 (2012). https://doi.org/10.1038/clpt.2012.68
- DrugBank http://www.drugbank.ca/drugs/DB00186 (Accessed 2013-09-16).