생체재료학회지 (Biomaterials Research)

  • 제19권4호
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  • Pages.195-202
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  • 2015
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  • 1226-4601(pISSN)
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  • 2055-7124(eISSN)
한국생체재료학회 (Korean Society for Biomaterials)
권호 표지
DOI QR코드

DOI QR Code

Preparation and investigation of hydrolyzed polyacrylonitrile as a preliminary biomedical hydrogel

  • Park, Ji Hoon (Department of Molecular Science and Technology, Ajou University) ;
  • Tai, Guo Zhe (Department of Molecular Science and Technology, Ajou University) ;
  • Lee, Bo Keun (Department of Molecular Science and Technology, Ajou University) ;
  • Park, Seung Hun (Department of Molecular Science and Technology, Ajou University) ;
  • Jang, Ja Yong (Department of Molecular Science and Technology, Ajou University) ;
  • Lee, Jung Soo (Department of Molecular Science and Technology, Ajou University) ;
  • Kim, Jae Ho (Department of Molecular Science and Technology, Ajou University) ;
  • Park, Kwideok (Center for Biomaterials, Korea Institute of Science and Technology) ;
  • Jang, Ju Woong (R&DB Center, Cellumed Co., Ltd.) ;
  • Kim, Moon Suk (Department of Molecular Science and Technology, Ajou University)
  • 투고 : 2015.09.01
  • 심사 : 2015.10.19
  • 발행 : 2015.12.31
⟨ 이전 논문 다음 논문 ⟩

초록

Background: Hydrolyzed polyacrylonitrile (HPAN) has attracted much attention as a hydrogel for a broad range of biomedical applications. Therefore, in this study, we prepared HPAN derivatives with controllable compositions by the radical polymerization of acrylonitrile (AN), methacrylic acid (MAA) and N-isopropylacrylamide (NIPAM) monomers. Results: The prepared poly(AN-co-MAA-co-NIPAM) copolymers had different ratios of AN, MAA, and NIPAM and molecular weights ranging from 2000 to 50,000. The copolymers were prepared as films to examine their properties. The prepared copolymer films showed different solubilities, contact angles, and swelling ratios. The properties of the copolymer films were affected by the hydrophobic PAN segments and the hydrophilic PMAA or PNIPAM segments. Conclusion: Thus, we conclude that introducing PMAA and PNIPAM segments with different ratios and lengths into PAN segments could represent a method of controlling the hydrogel properties of copolymers.

키워드

과제정보

연구 과제 주관 기관 : National Research Foundation of Korea (NRF)

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