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Behaviors of stem cells on carbon nanotube

  • Lee, Ju-Ro (School of Chemical and Biological Engineering, Seoul National University) ;
  • Ryu, Seungmi (Interdisciplinary Program for Bioengineering, Seoul National University) ;
  • Kim, Soojin (Department of Biomedical Engineering, University of Alabama at Birmingham) ;
  • Kim, Byung-Soo (School of Chemical and Biological Engineering, Seoul National University)
  • Received : 2014.07.30
  • Accepted : 2014.12.11
  • Published : 2015.03.31

Abstract

Regulating stem cell microenvironment is one of the essential elements in stem cell culture. Recently, carbon nanotube (CNT) has come into the spotlight as a biomaterial that retains unique properties. Based on its high chemical stability, elasticity, mechanical strength, and electrical conductivity, CNT shows great potential as an application for biomedical substrate. Also, properties of CNT could be further regulated by appropriate chemical modifications of CNT. Recent studies reported that modulating the cellular microenvironment through the use of CNT and chemically modified CNT as cell culture substrates can affect proliferation and differentiation of various types of stem cells. This review summarizes the unique biological effects of CNT on stem cells.

Keywords

Acknowledgement

Supported by : Korea Health Industry Development Institute (KHIDI)

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