Journal of Korean Neurosurgical Society

  • 제57권2호
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  • Pages.94-99
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  • 2015
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  • 2005-3711(pISSN)
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  • 1598-7876(eISSN)
대한신경외과학회 (The Korean Neurosurgical Society)
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Association of Carotid Intraplaque Hemorrhage and Territorial Acute Infarction in Patients with Acute Neurological Symptoms Using Carotid Magnetization-Prepared Rapid Acquisition with Gradient-Echo

  • Park, Jung Soo (Department of Neurosurgery, Chonbuk National University Medical School and Hospital) ;
  • Kwak, Hyo Sung (Department of Radiology, Chonbuk National University Medical School and Hospital) ;
  • Lee, Jong Myong (Department of Neurosurgery, Chonbuk National University Medical School and Hospital) ;
  • Koh, Eun Jeong (Department of Neurosurgery, Chonbuk National University Medical School and Hospital) ;
  • Chung, Gyung Ho (Department of Radiology, Chonbuk National University Medical School and Hospital) ;
  • Hwang, Seung Bae (Department of Radiology, Chonbuk National University Medical School and Hospital)
  • 투고 : 2014.07.14
  • 심사 : 2014.10.22
  • 발행 : 2015.02.28
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초록

Objective : The purpose of our study was to assess prevalence of carotid intraplaque hemorrhage (IPH) and associations between territorial acute infarction and IPH on magnetization-prepared rapid acquisition with gradient-echo (MPRAGE) in patients with acute neurologic symptoms. Methods : 83 patients with suspected acute neurologic symptoms were evaluated with both brain diffusion weighted imaging (DWI) and carotid MPRAGE sequences. Carotid plaque with high signal intensity on MPRAGE of >200% that of adjacent muscle was categorized as IPH. We analyzed the prevalence of IPH and its correlation with territorial acute infarction. Results : Of 166 arteries, 39 had a carotid artery plaque. Of these arteries, 26 had carotid artery stenosis less than 50%. In all carotid arteries, MR-depicted IPH was found in 7.2% (12/166). High-signal intensity on DWI was found in 17.5% (29/166). Combined lesion with ipsilateral high-signal intensity on DWI and IPH on carotid MPRAGE sequence was found in 6 lesions (6/166, 3.6%). Of patients with carotid artery plaque, MR-predicted IPH was found in 30.8% (12/39) and match lesions with high-signal intensity on DWI and MPRAGE was found in 15.4% (6/39). MR-predicted IPH was significantly higher prevalence in high-grade stenosis group (p=0.010). Relative risk between carotid MPRAGE-positive signal and ipsilateral high-signal intensity on DWI in arteries with carotid artery plaques was 6.8 (p=0.010). Conclusion : Carotid MPRAGE-positive signal in patients was associated with an increased risk of territorial acute infarction as detected objectively by brain DWI. The relative risk of stroke was increased in high-grade stenosis categories.

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참고문헌

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피인용 문헌

  1. Carotid Plaque Morphology Is Significantly Associated With Sex, Age, and History of Neurological Symptoms vol.46, pp.11, 2015, https://doi.org/10.1161/strokeaha.115.010558
  2. Carotid Intraplaque Hemorrhage Imaging: Diagnostic Value of High Signal Intensity Time-of-Flight MR Angiography Compared with Magnetization-Prepared Rapid Acquisition with Gradient-Echo Sequencing vol.22, pp.2, 2018, https://doi.org/10.13104/imri.2018.22.2.94
  3. Diagnostic performance of MRI for detecting intraplaque hemorrhage in the carotid arteries: a meta-analysis vol.29, pp.10, 2015, https://doi.org/10.1007/s00330-019-06053-7
  4. The usefulness of Time-of-Flight MR angiography in detection of intraplaque hemorrhage in patients with acute ischemic stroke with symptomatic carotid stenosis vol.15, pp.2, 2020, https://doi.org/10.1371/journal.pone.0229024