Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
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Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report

  • Lee, Yong Bin (Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry) ;
  • Kim, Nam-Kyoo (Department of Dentistry, Catholic Kwandong University International St. Mary's Hospital) ;
  • Kim, Jae-Young (Department of Oral and Maxillofacial Surgery, Gangnam Severance Hospital, Yonsei University College of Dentistry) ;
  • Kim, Hyung Jun (Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry)
  • Received : 2014.07.21
  • Accepted : 2014.09.29
  • Published : 2015.02.28
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Abstract

Cemento-ossifying fibromas are benign tumors, and, although cases of an aggressive type have been reported, no cases of cemento-ossifying fibroma transforming into osteosarcoma have been documented previously. Low-grade osteosarcoma is a rare type of primary bone tumor, representing 1%-2% of all osteosarcomas. A 45-year-old female patient was diagnosed with cemento-ossifying fibroma, treated with mass excision several times over a period of two years and eight months, and followed up. After biopsy gathered because of signs of recurrence, she was diagnosed with low-grade osteosarcoma. The patient underwent wide excision, segmental mandibulectomy, and reconstruction with fibula free flap. The aim of this report is to raise awareness of the possibility that cemento-ossifying fibroma can transform into osteosarcoma and of the consequent necessity for careful diagnosis and treatment planning.

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References

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