DOI QR코드

DOI QR Code

Molecular epidemiology of norovirus in South Korea

  • Lee, Sung-Geun (Korea Zoonosis Research Institute, Chonbuk National University) ;
  • Cho, Han-Gil (Division of Public Health Research, Gyeonggi Province Institute of Health and Environment) ;
  • Paik, Soon-Young (Department of Microbiology, College of Medicine, The Catholic University of Korea)
  • 투고 : 2014.12.01
  • 발행 : 2015.02.28

초록

Norovirus is a major cause of viral gastroenteritis and a common cause of foodborne and waterborne outbreaks. Norovirus outbreaks are responsible for economic losses, most notably to the public health and food industry field. Norovirus has characteristics such as low infectious dose, prolonged shedding period, strong stability, great diversity, and frequent genome mutations. Besides these characteristics, they are known for rapid and extensive spread in closed settings such as hospitals, hotels, and schools. Norovirus is well known as a major agent of food-poisoning in diverse settings in South Korea. For these reasons, nationwide surveillance for norovirus is active in both clinical and environmental settings in South Korea. Recent studies have reported the emergence of variants and novel recombinants of norovirus. In this review, we summarized studies on the molecular epidemiology and nationwide surveillance of norovirus in South Korea. This review will provide information for vaccine development and prediction of new emerging variants of norovirus in South Korea.

키워드

참고문헌

  1. Patel MM, Hall AJ, Vinjé J and Parashar UD (2009) Noroviruses: a comprehensive review. J Clin Virol 44, 1-8 https://doi.org/10.1016/j.jcv.2008.10.009
  2. Hall AJ, Wikswo ME, Pringle K, Gould LH and Parashar UD (2014) Vital signs: foodborne norovirus outbreaks - United States, 2009-2012. MMWR Morb Mortal Wkly Rep 63, 491-495
  3. Hall AJ, Lopman BA, Payne DC et al (2013) Norovirus disease in the United States. Emerg Infect Dis 19, 1198-1205 https://doi.org/10.3201/eid1908.130465
  4. Hall AJ, Vinje J, Lopman B et al (2011) Updated norovirus outbreak management and disease prevention guidelines. MMWR Morb Mortal Wkly Rep 60, 1-15
  5. Glass RI, Parashar UD and Estes MK (2009) Norovirus gastroenteritis. N Engl J Med 361, 1776-1785 https://doi.org/10.1056/NEJMra0804575
  6. Hardy ME (2005) Norovirus protein structure and function. FEMS Microbiol Lett 253, 1-8 https://doi.org/10.1016/j.femsle.2005.08.031
  7. Katayama K, Murakami K, Sharp TM et al (2014) Plasmidbased human norovirus reverse genetics system produces reporter-tagged progeny virus containing infectious genomic RNA. Proc Natl Acad Sci U S A 111, E4043-E4052 https://doi.org/10.1073/pnas.1415096111
  8. Tan M and Jiang X (2005) The p domain of norovirus capsid protein forms a subviral particle that binds to histo-blood group antigen receptors. J Virol 79, 14017-14030 https://doi.org/10.1128/JVI.79.22.14017-14030.2005
  9. Donaldson EF, Lindesmith LC, Lobue AD and Baric RS (2010) Viral shape-shifting: norovirus evasion of the human immune system. Nat Rev Microbiol 8, 231-241 https://doi.org/10.1038/nrmicro2296
  10. Thorne LG and Goodfellow IG (2014) Norovirus gene expression and replication. J Gen Virol 95, 278-291 https://doi.org/10.1099/vir.0.059634-0
  11. Caddy S, Breiman A, le Pendu J and Goodfellow I (2014) Genogroup IV and VI canine noroviruses interact with histo-blood group antigens. J Virol 88, 10377-10391 https://doi.org/10.1128/JVI.01008-14
  12. Fankhauser RL, Monroe SS, Noel JS et al (2002) Epidemiologic and molecular trends of "Norwalk-like viruses" associated with outbreaks of gastroenteritis in the United States. J Infect Dis 186, 1-7 https://doi.org/10.1086/341085
  13. Hasing ME, Lee BE, Preiksaitis JK et al (2013) Emergence of a new norovirus GII.4 variant and changes in the historical biennial pattern of norovirus outbreak activity in Alberta, Canada, from 2008 to 2013. J Clin Microbiol 51, 2204-2211 https://doi.org/10.1128/JCM.00663-13
  14. Vega E, Barclay L, Gregoricus N, Shirley SH, Lee D and Vinjé J (2014) Genotypic and epidemiologic trends of norovirus outbreaks in the United States, 2009 to 2013. J Clin Microbiol 52, 147-155 https://doi.org/10.1128/JCM.02680-13
  15. Lindesmith LC, Beltramello M, Donaldson EF et al (2012) Immunogenetic mechanisms driving norovirus GII.4 antigenic variation. PLoS Pathog 8, e1002705 https://doi.org/10.1371/journal.ppat.1002705
  16. Siebenga JJ, Lemey P, Kosakovsky Pond SL et al (2010) Phylodynamic reconstruction reveals norovirus GII.4 epidemic expansionsand their molecular determinants. PLoS Pathog 6, e1000884 https://doi.org/10.1371/journal.ppat.1000884
  17. Eden JS, Tanaka MM, Boni MF, Rawlinson WD and White PA (2013) Recombination within the pandemic norovirus GII.4 lineage. J Virol 87, 6270-6282 https://doi.org/10.1128/JVI.03464-12
  18. Mans J, Murray TY and Taylor MB (2014) Novel norovirus recombinants detected in South Africa. Virol J 11, 168 https://doi.org/10.1186/1743-422X-11-168
  19. Jia LP, Qian Y, Zhang Y et al (2014) Prevalence and genetic diversity of noroviruses in outpatient pediatric clinics in Beijing, China 2010-2012. Infect Genet Evol 28, 71-77 https://doi.org/10.1016/j.meegid.2014.09.006
  20. Moon S, Sohn IW, Hong Y et al (2014) Emerging Pathogens and Vehicles of Food- and Water-borne Disease Outbreaks in Korea, 2007-2012. Osong Public Health Res Perspect 5, 34-39 https://doi.org/10.1016/j.phrp.2013.12.004
  21. Yoon JS, Lee SG, Hong SK et al (2008) Molecular epidemiology of norovirus infections in children with acute gastroenteritis in South Korea in November 2005 through November 2006. J Clin Microbiol 46, 1474-1477 https://doi.org/10.1128/JCM.02282-07
  22. Huh JW, Kim WH, Moon SG, Lee JB and Lim YH (2009) Viral etiology and incidence associated with acute gastroenteritis in a 5-year survey in Gyeonggi province, South Korea. J Clin Virol 44, 152-156 https://doi.org/10.1016/j.jcv.2008.11.016
  23. Park S, Jung J, Oh S et al (2012) Characterization of norovirus infections in Seoul, Korea. Microbiol Immunol 56, 700-707 https://doi.org/10.1111/j.1348-0421.2012.00494.x
  24. Park DJ, Kim JS, Park JY et al (2010) Epidemiological Analysis of Norovirus Infection between March 2007 and February 2010. Korean J Lab Med 30, 647-653 https://doi.org/10.3343/kjlm.2010.30.6.647
  25. So CW, Kim DS, Yu ST, Cho JH and Kim JD (2013) Acute viral gastroenteritis in children hospitalized in Iksan, Korea during December 2010-June 2011. Korean J Pediatr 56, 383-388 https://doi.org/10.3345/kjp.2013.56.9.383
  26. Chung JY, Han TH, Park SH, Kim SW and Hwang ES (2010) Detection of GII-4/2006b variant and recombinant noroviruses in children with acute gastroenteritis, South Korea. J Med Virol 82, 146-152 https://doi.org/10.1002/jmv.21650
  27. Mayet A, Andreo V, Bedubourg G et al (2011) Food-borne outbreak of norovirus infection in a French military parachuting unit, April 2011. Euro Surveill 16, 19930
  28. Vivancos R, Keenan A, Sopwith W et al (2010) Norovirus outbreak in a cruise ship sailing around the British Isles: investigation and multi-agency management of an international outbreak. J Infect 60, 478-485 https://doi.org/10.1016/j.jinf.2010.03.018
  29. Yu JH, Kim NY, Koh YJ and Lee HJ (2010) Epidemiology of foodborne Norovirus outbreak in Incheon, Korea. J Korean Med Sci 25, 1128-1133 https://doi.org/10.3346/jkms.2010.25.8.1128
  30. Yu JH, Kim NY, Lee EJ and Jeon IS (2011) Norovirus infections in asymptomatic food handlers in elementary schools without norovirus outbreaks in some regions of Incheon, Korea. J Korean Med Sci 26, 734-9 https://doi.org/10.3346/jkms.2011.26.6.734
  31. Jeong AY, Jeong HS, Lee JS et al (2013) Occurrence of norovirus infections in asymptomatic food handlers in South Korea. J Clin Microbiol 51, 598-600 https://doi.org/10.1128/JCM.01856-12
  32. Park JH, Jeong HS, Lee JS et al (2014) First norovirus outbreaks associated with consumption of green seaweed (Enteromorpha spp.) in South Korea. Epidemiol Infect 27, 1-7
  33. Kim SH, Cheon DS, Kim JH et al (2005) Outbreaks of gastroenteritis that occurred during school excursions in Korea were associated with several waterborne strains of norovirus. J Clin Microbiol 43, 4836-4839 https://doi.org/10.1128/JCM.43.9.4836-4839.2005
  34. Koh SJ, Cho HG, Kim BH and Choi BY (2011) An outbreak of gastroenteritis caused by norovirus-contaminated groundwater at a waterpark in Korea. J Korean Med Sci 26, 28-32 https://doi.org/10.3346/jkms.2011.26.1.28
  35. Lee MJ, Kim WH, Cho HG and Lee SS (2012) Epidemiological Study of Ground-waterborne Norovirus GI.3-associated Gastroenteritis Outbreaks in Gyeonggi Province of South Korea in May 2011. J Bacteriol Virol 42, 232-241 https://doi.org/10.4167/jbv.2012.42.3.232
  36. Cho HG, Lee SG, Kim WH et al (2014) Acute gastroenteritis outbreaks associated with ground-waterborne norovirus in South Korea during 2008-2012. Epidemiol Infect 142, 2604-2609 https://doi.org/10.1017/S0950268814000247
  37. Lee SG, Jheong WH, Suh CI et al (2011) Nationwide groundwater surveillance of noroviruses in South Korea, 2008. Appl Environ Microbiol 77, 1466-1474 https://doi.org/10.1128/AEM.01996-10
  38. Lee BR, Lee SG, Park JH et al (2013) Norovirus contamination levels in ground water treatment systems used for food-catering facilities in South Korea. Viruses 5, 1646- 1654 https://doi.org/10.3390/v5071646
  39. Joung HK, Han SH, Park SJ et al (2013) Nationwide surveillance for pathogenic microorganisms in groundwater near carcass burials constructed in South Korea in 2010. Int J Environ Res Public Health 10, 7126-7143 https://doi.org/10.3390/ijerph10127126
  40. Han TH, Kim CH, Chung JY, Park SH, and Hwang ES (2011) Emergence of norovirus GII-4/2008 variant and recombinant strains in Seoul, Korea. Arch Virol 156, 323-329 https://doi.org/10.1007/s00705-010-0844-4
  41. Won YJ, Park JW, Han SH et al (2013) Full-genomic analysis of a human norovirus recombinant GII.12/13 novel strain isolated from South Korea. PLoS One 8, e85063 https://doi.org/10.1371/journal.pone.0085063
  42. Le VP, Jung YC, Kang KS, Lim I, Myung SC and Kim W (2010) Genetic characterization of norovirus GII.4 2006b variants from Jeju island, South Korea. J Med Virol 82, 1065-1070 https://doi.org/10.1002/jmv.21761
  43. Park KS, Jeong HS, Baek KA et al (2010) Genetic analysis of norovirus GII.4 variants circulating in Korea in 2008. Arch Virol 155, 635-641 https://doi.org/10.1007/s00705-010-0627-y
  44. Park K, Yeo S, Jeong H et al (2012) Updates on the genetic variations of norovirus in sporadic gastroenteritis in Chungnam Korea, 2009-2010. Virol J 9, 29 https://doi.org/10.1186/1743-422X-9-29
  45. Cho HG, Lee SG, Kim JE et al (2014) Molecular epidemiology of norovirus GII.4 variants in children under 5 years with sporadic acute gastroenteritis in South Korea during 2006-2013. J Clin Virol 61, 340-344 https://doi.org/10.1016/j.jcv.2014.08.018
  46. Kim HS, Hyun J, Kim HS, Kim JS, Song W and Lee KM (2013) Emergence of GII.4 Sydney norovirus in South Korea during the winter of 2012-2013. J Microbiol Biotechnol 23, 1641-1643 https://doi.org/10.4014/jmb.1308.08053

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  3. Genetic and epidemiological analysis of norovirus from children with gastroenteritis in Botswana, 2013–2015 vol.18, pp.1, 2018, https://doi.org/10.1186/s12879-018-3157-y