Investigative Magnetic Resonance Imaging

Korean Society of Magnetic Resonance in Medicine (대한자기공명의과학회)
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A Rare Case of Diffuse Pachymeningeal Involvement of Multiple Myeloma

  • Yoon, Jehong (Department of Radiology, Kyung Hee University Hospital) ;
  • Kim, Eui Jong (Department of Radiology, Kyung Hee University Hospital) ;
  • Lee, Kyung Mi (Department of Radiology, Kyung Hee University Hospital) ;
  • Choi, Woo Suk (Department of Radiology, Kyung Hee University Hospital) ;
  • Park, Bong Jin (Department of Neurosurgery, Kyung Hee University Hospital)
  • Received : 2015.12.15
  • Accepted : 2015.12.22
  • Published : 2015.12.31
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Abstract

Intracranial involvement in multiple myeloma patients takes up around 1%, and is usually known to be present in the parietal bone or skull base in cases of skull vault involvement, while it presents in the dura and parenchyma in cases of intracranial involvement. Primary pachymeningeal invasion is even rarer with extremely rapid progression and very poor prognosis. It is our intent to report a case in which we had to differentiate multiple myeloma with other metastatic tumors, lymphoma, and leukemia with intracranial involvement. Our patient showed an osteolytic lesion of the skull with dural involvement and subdural mass formations.

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References

  1. Terada T. Multiple myeloma presenting as an intracranial plasmacytoma: a case report. Cases J 2009;2:9110 https://doi.org/10.1186/1757-1626-2-9110
  2. Cerase A, Tarantino A, Gozzetti A, et al. Intracranial involvement in plasmacytomas and multiple myeloma: a pictorial essay. Neuroradiology 2008;50:665-674 https://doi.org/10.1007/s00234-008-0390-x
  3. Munshi NC, Longo DL, Anderson KC. Plasma cell disorders. In Longo DL, Fauci AS, Kasper DL, eds. Harrison's principles of internal medicine. 18th ed. New York: The McGraw-Hill Education, 2011:936-944
  4. Schluterman KO, Fassas AB, Van Hemert RL, Harik SI. Multiple myeloma invasion of the central nervous system. Arch Neurol 2004;61:1423-1429 https://doi.org/10.1001/archneur.61.9.1423
  5. Pizzuti P, Pertuiset E, Chaumonnot F, et al. Neuromeningeal sites of multiple myeloma: 3 cases and review of the literature. Rev Med Interne 1997;18:646-651 https://doi.org/10.1016/S0248-8663(97)82467-8
  6. De Blay V, Misson N, Dardenne G, Dupuis MJ. Leptomeningeal myelomatosis mimicking a subdural haematoma. Neuroradiology 2000;42:735-737 https://doi.org/10.1007/s002340000379
  7. Roddie P, Collie D, Johnson P. Myelomatous involvement of the dura mater: a rare complication of multiple myeloma. J Clin Pathol 2000;53:398-399 https://doi.org/10.1136/jcp.53.5.398
  8. Moran CC, Anderson CC, Caldemeyer KS, Smith RR. Meningeal myelomatosis: CT and MR appearances. AJNR Am J Neuroradiol 1995;16:1501-1503