Journal of Yeungnam Medical Science
- Volume 32 Issue 2
- /
- Pages.85-89
- /
- 2015
- /
- 2799-8010(eISSN)
DOI QR Code
Role of urine osmolality as a predictor of the effectiveness of combined imipramine and desmopressin in the treatment of monosymptomatic nocturnal enuresis
- Lee, Kwon Soo (Department of Urology, College of Medicine, Yeungnam University) ;
- Chang, Jun Bo (Department of Urology, College of Medicine, Yeungnam University) ;
- Jang, Jae Yoon (Department of Urology, College of Medicine, Yeungnam University) ;
- Ko, Young Hwii (Department of Urology, College of Medicine, Yeungnam University) ;
- Park, Yong Hoon (Department of Pediatrics, College of Medicine, Yeungnam University) ;
- Song, Phil Hyun (Department of Urology, College of Medicine, Yeungnam University)
- Received : 2015.10.29
- Accepted : 2015.11.10
- Published : 2015.12.31
Abstract
Background: We examined the usefulness of urine osmolality, as a predictive factor in the treatment of monosymptomatic nocturnal enuresis (NE) with combination therapy of imipramine and desmopressin. Methods: From May 2014 to April 2015, 59 monosymptomatic NE patients participated in this study. Early morning urine osmolality was measured at 1 week and 1 day before combination therapy of imipramine and desmopressin, and at 1 week and 2 weeks after therapy. The response to combination therapy was evaluated at 3 months after treatment. The mean period of combination therapy was