Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
권호 표지
DOI QR코드

DOI QR Code

Burr hole drainage using urokinase for treatment of subacute subdural hematoma

아급성기 경막하 혈종 치료시 천공술 후 urokinase를 이용한 혈종배액술

  • Kim, Min-Su (Department of Neurosurgery, Yeungnam University College of Medicine) ;
  • Kim, Seong-Ho (Department of Neurosurgery, Yeungnam University College of Medicine) ;
  • Kim, Oh-Lyong (Department of Neurosurgery, Yeungnam University College of Medicine)
  • 김민수 (영남대학교 의과대학 신경외과학교실) ;
  • 김성호 (영남대학교 의과대학 신경외과학교실) ;
  • 김오룡 (영남대학교 의과대학 신경외과학교실)
  • Received : 2015.03.30
  • Accepted : 2015.05.10
  • Published : 2015.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Background: Enlargement of subdural hematomas is relatively rapid in subacute stage of hematoma with clinical deterioration, which eventually necessitates surgery. The purpose of this study is to investigate the feasibility and safety of burr hole drainage using urokinase for management of patients with subacute subdural hematoma (SASDH). Methods: Nine patients with SASDH were treated by burr hole drainage using urokinase. Under local anesthesia a catheter was inserted into the hematoma through a burr hole. Burr hole drainage was followed by hematoma thrombolysis with instillation of urokinase (10,000 units) every 12 hours. Drainage was discontinued when a significant decrease of hematoma was observed on cranial computed tomography. Results: The patients' median age was 70 years (range, 62-87). The median Glasgow Coma Scale score before surgery was 15 (range, 11-15). Drainage was successfully performed in all patients. All patients had Glasgow Outcome Scale scores of 5 at discharge. There was no surgery-related morbidity or mortality. Conclusion: A burr hole drainage using urokinase could be a safe, feasible and effective minimally invasive method with low morbidity in treatment of selected patients with SASDHs.

Keywords