References
- Adrian, T.E., Allen, J.M., Bloom, S.R., Ghatei, M.A., Rossor, M.N., Roberts, G.W., Crow, T.J., Tatemoto, K., and Polak, J.M. (1983). Neuropeptide Y distribution in human brain. Nature 306, 584-586. https://doi.org/10.1038/306584a0
- Allen, Y.S., Adrian, T.E., Allen, J.M., Tatemoto, K., Crow, T.J., Bloom, S.R., and Polak, J.M. (1983). Neuropeptide Y distribution in the rat brain. Science 221, 877-879. https://doi.org/10.1126/science.6136091
- Almli, L.M., Mercer, K.B., Kerley, K., Feng, H., Bradley, B., Conneely, K.N., and Ressler, K.J. (2013). ADCYAP1R1 genotype associates with post-traumatic stress symptoms in highly traumatized African-American females. Am. J. Med. Genet. B Neuropsychiatr. Genet. 162B, 262-272.
- Aragam, N., Wang, K.S., and Pan, Y. (2011). Genome-wide association analysis of gender differences in major depressive disorder in the Netherlands NESDA and NTR population-based samples. J. Affect Disord. 133, 516-521. https://doi.org/10.1016/j.jad.2011.04.054
- Arzt, E., and Holsboer, F. (2006). CRF signaling, molecular specificity for drug targeting in the CNS. Trends Pharmacol. Sci. 27, 531-538. https://doi.org/10.1016/j.tips.2006.08.007
- Aston-Jones, G., and Harris, G.C. (2004). Brain substrates for increased drug seeking during protracted withdrawal. Neuropharmacology 46, 167-179.
- Beal, M.F., Mazurek, M.F., and Martin, J.B. (1987). A comparison of somatostatin and neuropeptide Y distribution in monkey brain. Brain Res. 405, 213-219. https://doi.org/10.1016/0006-8993(87)90290-3
- Beal, M.F., Mazurek, M.F., Ellison, D.W., Swartz, K.J., McGarvey, U., Bird, E.D., and Martin, J.B. (1988). Somatostatin and neuropeptide Y concentrations in pathologically graded cases of Huntington's disease. Ann. Neurol. 23, 562-569. https://doi.org/10.1002/ana.410230606
- Betley, J.N., Cao, Z.F., Ritola, K.D., and Sternson, S.M. (2013). Parallel, redundant circuit organization for homeostatic control of feeding behavior. Cell 155, 1337-1350. https://doi.org/10.1016/j.cell.2013.11.002
- Binder, E.B., Kinkead, B., Owens, M.J., and Nemeroff, C.B. (2001). Neurotensin and dopamine interactions. Pharmacol. Rev. 53, 453-486.
- Blank, T., Nijholt, I., Grammatopoulos, D.K., Randeva, H.S., Hillhouse, E.W., and Spiess, J. (2003). Corticotropin-releasing factor receptors couple to multiple G-proteins to activate diverse intracellular signaling pathways in mouse hippocampus, role in neuronal excitability and associative learning. J. Neurosci. 23.
- Boom, A., Mollereau, C., Meunier, J.C., Vassart, G., Parmentier, M., Vanderhaeghen, J.J., and Schiffmann, S.N. (1999). Distribution of the nociceptin and nocistatin precursor transcript in the mouse central nervous system. NSC 91, 991-1007.
- Botchkina, G.I., and Morin, L.P. (1995). Organization of permanent and transient neuropeptide Y-immunoreactive neuron groups and fiber systems in the developing hamster diencephalon. J. Comp. Neurol. 357, 573-602. https://doi.org/10.1002/cne.903570408
- Browning, J.R., Jansen, H.T., and Sorg, B.A. (2014). Inactivation of the paraventricular thalamus abolishes the expression of cocaine conditioned place preference in rats. Drug Alcohol Depend. 134, 387-390. https://doi.org/10.1016/j.drugalcdep.2013.09.021
- Bruchas, M.R., Land, B.B., Lemos, J.C., and Chavkin, C. (2009). CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior. PLoS One 4, e8528. https://doi.org/10.1371/journal.pone.0008528
- Bunzow, J.R., Saez, C., Mortrud, M., Bouvier, C., Williams, J.T., Low, M., and Grandy, D.K. (1994). Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type. FEBS Lett. 347, 284-288. https://doi.org/10.1016/0014-5793(94)00561-3
- Burghardt, N.S., and Bauer., E.P. (2013). Acute and chronic effects of selective serotonin reuptake inhibitor treatment on fear conditioning, implications for underlying fear circuits. Neuroscience 247, 253-272. https://doi.org/10.1016/j.neuroscience.2013.05.050
- Burroughs, L.F., Fiber, J.M., and Swann, J.M. (1996). Neuropeptide Y in hamster limbic nuclei, lack of colocalization with substance P. Peptides 17, 1053-1062. https://doi.org/10.1016/0196-9781(96)00130-1
- Caceda, R., Kinkead, B., and Nemeroff, C.B. (2006). Neurotensin, role in psychiatric and neurological diseases. Peptides 27, 2385-2404. https://doi.org/10.1016/j.peptides.2006.04.024
- Calcagnoli, F., de Boer, S.F., Beiderbeck, D.I., Althaus, M., Koolhaas, J.M., and Neumann, I.D. (2014). Local oxytocin expression and oxytocin receptor binding in the male rat brain is associated with aggressiveness. Behav. Brain Res. 261, 315-322. https://doi.org/10.1016/j.bbr.2013.12.050
- Carmichael, M.S., Humbert, R., Dixen, J., Palmisano, G., Greenleaf, W., and Davidson, J.M. (1987). Plasma oxytocin increases in the human sexual response. J. Clin. Endocrinol. Metab. 64, 27-31. https://doi.org/10.1210/jcem-64-1-27
- Carr, J.A. (2002). Stress, neuropeptides, and feeding behavior, A comparative perspective. Integr. Comp. Biol. 42, 582-590. https://doi.org/10.1093/icb/42.3.582
- Carty, M.L., Wixey, J.A., Kesby, J., Reinebrant, H.E., Colditz, P.B., Gobe, G., and Buller, K.M. (2010). Long-term losses of amygdala corticotropin-releasing factor neurons are associated with behavioural outcomes following neonatal hypoxia-ischemia. Behav. Brain Res. 208, 609-618. https://doi.org/10.1016/j.bbr.2010.01.007
- Chiba, T., Kayahara, T., and Nakano, K. (2001). Efferent projections of infralimbic and prelimbic areas of the medial prefrontal cortex in the Japanese monkey, Macaca fuscata. Brain Res. 888, 83-101. https://doi.org/10.1016/S0006-8993(00)03013-4
- Choi, D.C., Furay, A.R., Evanson, N.K., Ostrander, M.M., Ulrich-Lai, Y.M., and Herman, J.P. (2007). Bed nucleus of the stria terminalis subregions differentially regulate hypothalamic-pituitary-adrenal axis activity, implications for the integration of limbic inputs. J. Neurosci. 27, 2025-2034. https://doi.org/10.1523/JNEUROSCI.4301-06.2007
- Chronwall, B.M., DiMaggio, D.A., Massari, V.J., Pickel, V.M., Ruggiero, D.A., and O'Donohue, T.L. (1985). The anatomy of neuropeptide-Y-containing neurons in rat brain. Neuroscience 15, 1159-1181. https://doi.org/10.1016/0306-4522(85)90260-X
- Chung, S., Kim, H.J., Kim, H.J., Choi, S.H., Cho, J.H., Cho, Y.H., Kim, D.H., and Shin, K.H. (2014). Desipramine and citalopram attenuate pretest swim-induced increases in prodynorphin immunoreactivity in the dorsal bed nucleus of the stria terminalis and the lateral division of the central nucleus of the amygdala in the forced swimming test. Neuropeptides 48, 273-280. https://doi.org/10.1016/j.npep.2014.07.001
- Ciccocioppo, R., Biondini, M., Antonelli, L., Wichmann, J., Jenck, F., and Massi, M. (2002). Reversal of stress- and CRF-induced anorexia in rats by the synthetic nociceptin/orphanin FQ receptor agonist, Ro 64-6198. Psychopharmacology 161, 113-119. https://doi.org/10.1007/s00213-002-1020-7
- Ciccocioppo, R., Cippitelli, A., Economidou, D., Fedeli, A., and Massi, M. (2004). Nociceptin/orphanin FQ acts as a functional antagonist of corticotrophin-releasing factor to inhibit its anorectic effect. Physiol. Behav. 82, 63-68. https://doi.org/10.1016/j.physbeh.2004.04.035
- Ciccocioppo, R., Fedeli, A., Economidou, D., Policani, F., Weiss, F., and Massi, M. (2003a). The bed nucleus is a neuroanatomical substrate for the anorectic effect of corticotrophin-releasing factor and for its reversal by nociceptin/orphanin FQ. J. Neurosci. 23, 9445-9451.
- Ciccocioppo, R., Fedeli, A., Economidou, D., Policani, F., Weiss, F., and Massi, M. (2003b). The bed nucleus is a neuroanatomical substrate for the anorectic effect of corticotropin-releasing factor and for its reversal by nociceptin/orphanin FQ. J. Neurosci. 23, 9445-9451.
- Cippitelli, A., Damadzic, R., Hansson, A.C., Singley, E., Sommer, W.H., Eskay, R., Thorsell, A., and Heilig, M. (2010). Neuropeptide Y (NPY) suppresses yohimbine-induced reinstatement of alcohol seeking. Psychopharmacology 208, 417-426. https://doi.org/10.1007/s00213-009-1741-y
- Cummings, S., Elde, R., Ells, J., and Lindall, A. (1983). Corticotropinreleasing factor immunoreactivity is widely distributed within the central nervous system of the rat, an immunohistochemical study. J. Neurosci. 3, 1355-1368.
- D'Este, L., Casini, A., Pontieri, F.E., and Renda, T.G. (2006). Changes in neuropeptide FF and NPY immunohistochemical patterns in rat brain under heroin treatment. Brain Res. 1083, 151-158. https://doi.org/10.1016/j.brainres.2006.02.009
- Dabrowska, J., Hazra, R., Guo, J.D., DeWitt, S., and Rainnie, D.G. (2013). Central CRF neurons are not created equal, phenotypic differences in CRF-containing neurons of the rat paraventricular hypothalamus and the bed nucleus of the stria terminalis. Front Neurosci. 7, 1-14.
- Dale, H.H. (1906). On some physiological actions of ergot. J. Physiol. 34, 163-206. https://doi.org/10.1113/jphysiol.1906.sp001148
- Dautenberg, F.M., and Hauger, R.L. (2002). The CRF peptide family and their receptors, yet more partners discovered. Trends Pharmacol. Sci. 23, 71-77. https://doi.org/10.1016/S0165-6147(02)01946-6
- Davis, M., and Shi, C. (1999). The extended amygdala, are the central nucleus of the amygdala and the bed nucleus of the stria terminalis differentially involved in fear versus anxiety? Ann. N Y Acad. Sci. 877, 281-291. https://doi.org/10.1111/j.1749-6632.1999.tb09273.x
- Davis, M., and Walker, D.L. (2013). Role of bed nucleus of the stria terminalis and amygdala AMPA receptors in the development and expression of context conditioning and sensitization of startle by prior shock. Brain Struct. Funct. [Epub ahead of print].
- Davis, M., Walker, D.L., and Lee, Y. (1997a). Amygdala and bed nucleus of the stria terminalis, differential roles in fear and anxiety measured with the acoustic startle reflex. Philos. Trans. R Soc. Lond. B Biol. Sci. 352, 1675-1687. https://doi.org/10.1098/rstb.1997.0149
- Davis, M., Walker, D.L., and Lee, Y. (1997b). Roles of the amygdala and bed nucleus of the stria terminalis in fear and anxiety measured with the acoustic startle reflex. Possible relevance to PTSD. Ann. N Y Acad. Sci. 821, 305-331. https://doi.org/10.1111/j.1749-6632.1997.tb48289.x
- Dawe, K.L., Wakerley, J.B., and Fulford, A.J. (2010). Nociceptin/ orphanin FQ and the regulation of neuronal excitability in the rat bed nucleus of the stria terminalis, Interaction with glucocorticoids. Stress 13, 516-527. https://doi.org/10.3109/10253890.2010.491134
- de Campo, D.M., and Fudge, J.L. (2013). Amygdala projections to the lateral bed nucleus of the stria terminalis in the macaque, comparison with ventral striatal afferents. J. Comp. Neurol. 521, 3191-3216. https://doi.org/10.1002/cne.23340
- Desai, S.J., Upadhya, M.A., Subhedar, N.K., and Kokare, D.M. (2013). NPY mediates reward activity of morphine, via NPY Y1 receptors, in the nucleus accumbens shell. Behav. Brain Res. 247, 79-91.
- Desai, S.J., Borkar, C.D., Nakhate, K.T., Subhedar. N.K., and Kokare, D.M. (2014). Neuropeptide Y attenuates anxiety- and depressionlike effects of cholecystokinin-4 in mice. Neuroscience 277C, 818-830.
- Dong, H.W., Petrovich, G.D., and Swanson, L.W. (2001a). Topography of projections from amygdala to bed nuclei of the stria terminalis. Brain Res.earch. Brain Res. Rev. 38, 192-246. https://doi.org/10.1016/S0165-0173(01)00079-0
- Dong, H.W., Petrovich, G.D., Watts, A.G., and Swanson, L.W. (2001b). Basic organization of projections from the oval and fusiform nuclei of the bed nuclei of the stria terminalis in adult rat brain. J. Comp. Neurol. 436, 430-455. https://doi.org/10.1002/cne.1079
- Dore, R., Iemolo, A., Smith, K.L., Wang, X., Cottone, P., and Sabino, V. (2013). CRF mediates the anxiogenic and anti-rewarding, but not the anorectic effects of PACAP. Neuropsychopharmacology 38, 2160-2169. https://doi.org/10.1038/npp.2013.113
- du Vigneaud, V., Ressler, C., and Trippett, S. (1953). THE SEQUENCE OF AMINO ACIDS IN OXYTOCIN, WITH A PROPOSAL FOR THE STRUCTURE OF OXYTOCIN. J. Biol. Chem. 205, 949-957.
- Dumont, Y., Fournier, A., St-Pierre, S., and Quirion, R. (1996). Autoradiographic distribution of [125I]Leu31,Pro34]PYY and [125I]PYY3-36 binding sites in the rat brain evaluated with two newly developed Y1 and Y2 receptor radioligands. Synapse 22, 139-158. https://doi.org/10.1002/(SICI)1098-2396(199602)22:2<139::AID-SYN7>3.0.CO;2-E
- Duvarci, S., Bauer, E.P., and Pare, D. (2009). The bed nucleus of the stria terminalis mediates inter-individual variations in anxiety and fear. J. Neurosci. 29, 10357-10361. https://doi.org/10.1523/JNEUROSCI.2119-09.2009
- Eiler, W.J., 2nd, Seyoum, R., Foster, K.L., Mailey, C., and June, H.L. (2003). D1 dopamine receptor regulates alcohol-motivated behaviors in the bed nucleus of the stria terminalis in alcoholpreferring (P) rats. Synapse 48, 45-56. https://doi.org/10.1002/syn.10181
- Elharrar, E., Warhaftig, G., Issler, O., Sztainberg, Y., Dikshtein, Y., Zahut, R., Redlus, L., Chen, A., and Yadid, G. (2013). Overexpression of corticotropin-releasing factor receptor type 2 in the bed nucleus of stria terminalis improves posttraumatic stress disorder-like symptoms in a model of incubation of fear. Biol. Psychiat. 74, 827-836. https://doi.org/10.1016/j.biopsych.2013.05.039
- Epping-Jordan, M.P., Markou, A., and Koob, G.F. (1998). The dopamine D-1 receptor antagonist SCH 23390 injected into the dorsolateral bed nucleus of the stria terminalis decreased cocaine reinforcement in the rat. Brain Res. 784, 105-115. https://doi.org/10.1016/S0006-8993(97)01190-6
- Erb, S. (2010). Evaluation of the relationship between anxiety during withdrawal and stress-induced reinstatement of cocaine seeking. Progr. Neuro-psychoph. 34, 798-807. https://doi.org/10.1016/j.pnpbp.2009.11.025
- Erb, S., and Stewart, J. (1999). A role for the bed nucleus of the stria terminalis, but not the amygdala, in the effects of corticotrophin-releasing factor on stress-induced reinstatement of cocaine seeking. J. Neurosci. 19, RC35.
- Erb, S., Salmaso, N., Rodaros, D., and Stewart, J. (2001). A role for the CRF-containing pathway from central nucleus of the amygdala to bed nucleus of the stria terminalis in the stressinduced reinstatement of cocaine seeking in rats. Psychopharmacology 158, 360-365. https://doi.org/10.1007/s002130000642
- Fallon, J.H., and Leslie, F.M. (1986). Distribution of dynorphin and enkephalin peptides in the rat brain. J. Comp. Neurol. 249, 293-336. https://doi.org/10.1002/cne.902490302
- Flavin, S.A., and Winder, D.G. (2013). Noradrenergic control of the bed nucleus of the stria terminalis in stress and reward. Neuropharmacology 70, 324-330. https://doi.org/10.1016/j.neuropharm.2013.02.013
- Francesconi, W., Berton, F., Repunte-Canonigo, V., Hagihara, K., Thurbon, D., Lekic, D., Specio, S.E., Greenwell, T.N., Chen, S.A., Rice, K.C., et al. (2009). Protracted withdrawal from alcohol and drugs of abuse impairs long-term potentiation of intrinsic excitability in the juxtacapsular bed nucleus of the stria terminalis. J. Neurosci. 29, 5389-5401. https://doi.org/10.1523/JNEUROSCI.5129-08.2009
- Fu, Y., and Neugebauer, V. (2008). Differential mechanisms of CRF1 and CRF2 receptor functions in the amygdala in painrelated synaptic facilitation and behavior. J. Neurosci. 28, 3861-3876. https://doi.org/10.1523/JNEUROSCI.0227-08.2008
- Funk, C.K., O'Dell, L.E., Crawford, E.F., and Koob, G.F. (2006a). Corticotropin-releasing factor within the central nucleus of the amygdala mediates enhanced ethanol self-administration in withdrawn, ethanol-dependent rat. J. Neurosci. 26, 11324-11332. https://doi.org/10.1523/JNEUROSCI.3096-06.2006
- Funk, D., Li, Z., and Le, A.D. (2006b). Effects of environmental and pharmacological stressors on c-fos and corticotropin-releasing factor mRNA in rat brain, Relationship to the reinstatement of alcohol seeking. Neuroscience 138, 235-243. https://doi.org/10.1016/j.neuroscience.2005.10.062
- Gafford, G.M., Guo, J.D., Flandreau, E.I., Hazra, R., Rainnie, D.G., and Ressler, K.J. (2012). Cell-type specific deletion of GABA(A)1 in corticotrophin-releasing factor-containing neurons enhances anxiety and disrupts fear extinction. Proc. Natl. Acad. Sci. USA 109, 16330-16335. https://doi.org/10.1073/pnas.1119261109
- Garcia-Carmona, J.A., Milanes, M.V., and Laorden, M.L. (2013). Brain stress system response after morphine-conditioned place preference. Int. J. Neuropsychopharmacol. 16, 1999-2011. https://doi.org/10.1017/S1461145713000588
- Gaspar, P., Berger, B., Lesur, A., Borsotti, J.P., and Febvret, A. (1987). Somatostatin 28 and neuropeptide Y innervation in the septal area and related cortical and subcortical structures of the human brain. Distribution, relationships and evidence for differential coexistence. Neuroscience 22, 49-73. https://doi.org/10.1016/0306-4522(87)90197-7
- Gass, J.T., Trantham-Davidson, H., Kassab, A.S., Glen, W.B., Jr., Olive, M.F., and Chandler, L.J. (2014). Enhancement of extinction learning attenuates ethanol-seeking behavior and alters plasticity in the prefrontal cortex. J. Neurosci. 34, 7562-7574. https://doi.org/10.1523/JNEUROSCI.5616-12.2014
- Gaszner, B., Kormos, V., Kozicz, T., Hashimoto, H., Reglodi, D., and Helyes, Z. (2012). The behavioral phenotype of pituitary adenylate-cyclase activating polypeptide-deficient mice in anxiety and depression tests is accompanied by blunted c-Fos expression in the bed nucleus of the stria terminalis, central projecting Edinger-Westphal nucleus, ventral lateral septum, and dorsal raphe nucleus. Neuroscience 202, 283-299. https://doi.org/10.1016/j.neuroscience.2011.11.046
- Gavioli, E.C., Rizzi, A., Marzola, G., Zucchini, S., Regoli, D., and Calo, G. (2007). Altered anxiety-related behavior in nociceptin/ orphanin FQ receptor gene knockout mice. Peptides 28, 1229-1239. https://doi.org/10.1016/j.peptides.2007.04.012
- Gewirtz, J.C., McNish, K.A., and Davis, M. (1998). Lesions of the bed nucleus of the stria terminalis block sensitization of the acoustic startle reflex produced by repeated stress, but not fearpotentiated startle. Prog. Neuropsychopharmacol. Biol. Psychiatry 22, 625-648.
- Gimpl, G., and Fahrenholz, F. (2001). The oxytocin receptor system: structure, function, and regulation. Physiol. Rev. 81, 629-683. https://doi.org/10.1152/physrev.2001.81.2.629
- Girard, B.A., Lelievre, V., Braas, K.M., Razinia, T., Vizzard, M.A., Ioffe, Y., El Meskini, R., Ronnett, G.V., Waschek, J.A., and May, V. (2006). Noncompensation in peptide/receptor gene expression and distinct behavioral phenotypes in VIP- and PACAP-deficient mice. J. Neurochem. 99, 499-513. https://doi.org/10.1111/j.1471-4159.2006.04112.x
- Gray, T.S., and Magnuson, D.J. (1992). Peptide immunoreactive neurons in the amygdala and the bed nucleus of the stria terminalis project to the midbrain central gray in the rat. Peptides 13, 451-460. https://doi.org/10.1016/0196-9781(92)90074-D
- Guo, J.D., Hammack, S.E., Hazra, R., Levita, L., and Rainnie, D.G. (2009). Bi-directional modulation of bed nucleus of stria terminalis neurons by 5-HT, molecular expression and functional properties of excitatory 5-HT receptor subtypes. Neuroscience 164, 1776-1793. https://doi.org/10.1016/j.neuroscience.2009.09.028
- Hammack, S.E., Cheung, J., Rhodes, K.M., Schutz, K.C., Falls, W.A., Braas, K.M., and May, V. (2009). Chronic stress increases pituitary adenylate cyclase-activating peptide (PACAP) and brain-derived neurotrophic factor (BDNF) mRNA expression in the bed nucleus of the stria terminalis (BNST), roles for PACAP in anxiety-like behavior. Psychoneuroendocrinology 34, 833-843. https://doi.org/10.1016/j.psyneuen.2008.12.013
- Hammack, S.E., Cooper, M.A., and Lezak, K.R. (2012). Overlapping neurobiology of learned helplessness and conditioned defeat, implications for PTSD and mood disorders. Neuropharmacology 62, 565-575. https://doi.org/10.1016/j.neuropharm.2011.02.024
- Harmar, A.J., Arimura, A., Gozes, I., Journot, L., Laburthe, M., Pisegna, J.R., Rawlings, S.R., Robberecht, P., Said, S.I., Sreedharan, S.P., et al. (1998). International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide. Pharmacol. Rev. 50, 265-270.
- Hashimoto, H., Nogi, H., Mori, K., Ohishi, H., Shigemoto, R., Yamamoto, K., Matsuda, T., Mizuno, N., Nagata, S., and Baba, A. (1996). Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain, an in situ hybridization study. J. Comp. Neurol. 371, 567-577. https://doi.org/10.1002/(SICI)1096-9861(19960805)371:4<567::AID-CNE6>3.0.CO;2-2
- Hashimoto, H., Shintani, N., Tanaka, K., Mori, W., Hirose, M., Matsuda, T., Sakaue, M., Miyazaki, J., Niwa, H., Tashiro, F., et al. (2001). Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP). Proc. Natl. Acad. Sci. USA 98, 13355-13360. https://doi.org/10.1073/pnas.231094498
- Hashimoto, R., Hashimoto, H., Shintani, N., Chiba, S., Hattori, S., Okada, T., Nakajima, M., Tanaka, K., Kawagishi, N., Nemoto, K., et al. (2007). Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia. Mol. Psychiatr. 12, 1026-1032. https://doi.org/10.1038/sj.mp.4001982
- Hasue, R.H., and Shammah-Lagnado, S.J. (2002). Origin of dopaminergic innervations of the central extended amygdala and accumbens shell, a combined retrograde tracing and immunohistochemical study in the rat. J. Comp. Neurol. 454, 15-33. https://doi.org/10.1002/cne.10420
- Hattori, S., Takao, K., Tanda, K., Toyama, K., Shintani, N., Baba, A., Hashimoto, H., and Miyakawa, T. (2012). Comprehensive behavioral analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) knockout mice. Front Behav. Neurosci. 6, 58.
- Hawley, D.F., Bardi, M., Everette, A.M., Higgins, T.J., Tu, K.M., Kinsley, C.H., and Lambert, K.G. (2010). Neurobiological constituents of active, passive, and variable coping strategies in rats, integration of regional brain neuropeptide Y levels and cardiovascular responses. Stress 13, 172-183. https://doi.org/10.3109/10253890903144621
- Heilig, M. (2004). The NPY system in stress, anxiety and depression. Neuropeptides 38, 213-224. https://doi.org/10.1016/j.npep.2004.05.002
- Heilig, M., and Thorsell, A. (2002). Brain neuropeptide Y (NPY) in stress and alcohol dependence. Rev. Neurosci. 13, 85-94.
- Heilig, M., Koob, G.F., Ekman, R., and Britton, K.T. (1994). Corticotropin-releasing factor and neuropeptide Y, role in emotional integration. Trends Neurosci. 17, 80-85. https://doi.org/10.1016/0166-2236(94)90079-5
- Heisler, L.K., Zhou, L., Bajwa, P., Hsu, J., and Tecott, L.H. (2007). Serotonin 5-HT(2C) receptors regulate anxiety-like behavior. Genes Brain Behav. 6, 491-496. https://doi.org/10.1111/j.1601-183X.2007.00316.x
- Herr, N.R., Park, J., McElligott, Z.A., Belle, A.M., Carelli, R.M., and Wightman, R.M. (2012). In vivo voltammetry monitoring of electrically evoked extracellular norepinephrine in subregions of the bed nucleus of the stria terminalis. J. Neurophysiol. 107, 1731-1737. https://doi.org/10.1152/jn.00620.2011
- Heydendael, W., Sharma, K., Iyer, V., Luz, S., Piel, D., Beck, S., and Bhatnagar, S. (2011). Orexins/hypocretins act in the posterior paraventricular thalamic nucleus during repeated stress to regulate facilitation to novel stress. Endocrinology 152, 4738-4752. https://doi.org/10.1210/en.2011-1652
- Hollis, F., Duclot, F., Gunjan, A., and Kabbaj, M. (2011). Individual differences in the effect of social defeat on anhedonia and histone acetylation in the rat hippocampus. Horm. Behav. 59, 331-337. https://doi.org/10.1016/j.yhbeh.2010.09.005
- Hooker, J.M., Patel, V., Kothari, S., Schiffer, W.K. (2009). Metabolic changes in the rodent brain after acute administration of salvinorin A. Mol. Imaging Biol. 11, 137-143. https://doi.org/10.1007/s11307-008-0192-x
- Huang, M.M., Overstreet, D.H., Knapp, D.J., Angel, R., Wills, T.A., Navarro, M., Rivier, J., Vale, W., Breese, G.R. (2010). Corticotropin-Releasing Factor (CRF) sensitization of ethanol withdrawal-induced anxiety-like behavior is brain site specific and mediated by CRF-1 receptors, Relation to stress-induced sensitization. J. Pharmacol. Exp. Ther. 332, 298-307. https://doi.org/10.1124/jpet.109.159186
- Hurley, K.M., Herbert, H., Moga, M.M., and Saper, C.B. (1991). Efferent projections of the infralimbic cortex of the rat. J. Comp. Neurol. 308, 249-276. https://doi.org/10.1002/cne.903080210
- Ide, S., Hara, T., Ohno, A., Tamano, R., Koseki, K., Naka, T., Maruyama, C., Kaneda, K., Yoshioka, M., and Minami, M. (2013). Opposing roles of corticotropin-releasing factor and neuropeptide Y within the dorsolateral bed nucleus of the stria terminalis in the negative affective component of pain in rats. J. Neurosci. 33, 5881-5894. https://doi.org/10.1523/JNEUROSCI.4278-12.2013
- Ikeda, K., Watanabe, M., Ichikawa, T., Kobayashi, T., Yano, R., and Kumanishi, T. (1998). Distribution of prepro-nociceptin/orphanin FQ mRNA and its receptor mRNA in developing and adult mouse central nervous systems. J. Comp. Neurol. 399, 139-151. https://doi.org/10.1002/(SICI)1096-9861(19980914)399:1<139::AID-CNE11>3.0.CO;2-C
- Ingram, C.D., and Moos, F. (1992). Oxytocin-containing pathway to the bed nuclei of the stria terminalis of the lactating rat brain, Immunocytochemical and in vitro electrophysiological evidence. Neuroscience 47, 439-452. https://doi.org/10.1016/0306-4522(92)90258-4
- Ingram, C.D., Cutler, K.L., and Wakerley, J.B. (1990). Oxytocin excites neurones in the bed nucleus of the stria terminalis of the lactating rat in vitro. Brain Res. 527, 167-170. https://doi.org/10.1016/0006-8993(90)91078-U
- Insel, T.R. (1992). Oxytocin--a neuropeptide for affiliation, evidence from behavioral, receptor autoradiographic, and comparative studies. Psychoneuroendocrinology 17, 3-35. https://doi.org/10.1016/0306-4530(92)90073-G
- Insel, T.R., and Shapiro, L.E. (1992). Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles. Proc. Natl. Acad. Sci. USA 89, 5981-5985. https://doi.org/10.1073/pnas.89.13.5981
- Ishihara, T., and Shigemoto, R., Mori, K., Takahashi, K., Nagata, S. (1992). Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide. Neuron 8, 811-819. https://doi.org/10.1016/0896-6273(92)90101-I
- Jaworski, D.M., and Proctor, M.D. (2000). Developmental regulation of pituitary adenylate cyclase-activating polypeptide and PAC(1) receptor mRNA expression in the rat central nervous system. Brain Res. Dev. Brain Res. 120, 27-39. https://doi.org/10.1016/S0165-3806(99)00192-3
- Jennings, J.H., Sparta, D.R., Stamatakis, A.M., Ung, R.L., Pleil, K.E., Kash, T.L., and Stuber, G.D. (2013a). Distinct extended amygdala circuits for divergent motivational states. Nature 496, 224-228. https://doi.org/10.1038/nature12041
- Jennings, J.H., Sparta, D.R., Stamatakis, A.M., Ung, R.L., and Stuber, G.D. (2013b). The inhibitory circuit architecture of the lateral hypothalamus orchestrates feeding. Science 341, 1517-1521. https://doi.org/10.1126/science.1241812
- Kalamatianos, T., Faulkes, C.G., Oosthuizen, M.K., Poorun, R., Bennett, N.C., and Coen, C.W. (2010). Telencephalic binding sites for oxytocin and social organization, A comparative study of eusocial naked mole-rats and solitary cape mole-rats. J. Comp. Neurol. 518, 1792-1813. https://doi.org/10.1002/cne.22302
- Kash, T.L., and Winder, D.G. (2006). Neuropeptide Y and corticotropin-releasing factor bi-directionally modulate inhibitory synaptic transmission in the bed nucleus of the stria terminalis. Neuropharmacology 51, 1013-22. https://doi.org/10.1016/j.neuropharm.2006.06.011
- Kash, T.L., Baucum, A.J., 2nd, Conrad K.L., Colbran, R.J., and Winder, D.G. (2009). Alcohol exposure alters NMDAR function in the bed nucleus of the stria terminalis. Neuropsychopharmacology 34, 2420-2429. https://doi.org/10.1038/npp.2009.69
- Kempadoo, K.A., Tourino, C., Cho, S.L., Magnani, F., Leinninger, G.M., Stuber, G.D., Zhang, F., Myers, M.G., Deisseroth, K., de Lecea, L., et al. (2013). Hypothalamic neurotensin projections promote reward by enhancing glutamate transmission in the VTA. J. Neuroscience 33, 7618-7626. https://doi.org/10.1523/JNEUROSCI.2588-12.2013
- Kendrick, K.M., Keverne, E.B., Hinton, M.R., and Goode, J.A. (1992). Oxytocin, amino acid and monoamine release in the region of the medial preoptic area and bed nucleus of the stria terminalis of the sheep during parturition and suckling. Brain Res. 569, 199-209. https://doi.org/10.1016/0006-8993(92)90631-I
- Kim, S.Y., Adhikari, A., Lee, S.Y., Marshel, J.H., Kim, C.K., Mallory, C.S., Lo, M., Pak, S., Mattis, J., Lim, B.K., et al. (2013). Diverging neural pathways assemble a behavioural state from separable features in anxiety. Nature 496, 219-223. https://doi.org/10.1038/nature12018
- Kimura, C., Ohkubo, S., Ogi, K., Hosoya, M., Itoh, Y., Onda, H., Miyata, A., Jiang, L., Dahl, R.R., Stibbs, H.H., et al. (1990). A novel peptide which stimulates adenylate cyclase: molecular cloning and characterization of the ovine and human cDNAs. Biochem. Biophys. Res. Commun. 166, 81-89. https://doi.org/10.1016/0006-291X(90)91914-E
- Kinsey, S.G., Bailey, M.T., Sheridan, J.F., Padgett, D.A., and Avitsur, R. (2007). Repeated social defeat causes increased anxiety-like behavior and alters splenocyte function in C57BL/6 and CD-1 mice. Brain Behav. Immun. 21, 458-466. https://doi.org/10.1016/j.bbi.2006.11.001
- Kocho-Schellenberg, M., Lezak, K.R., Harris, O.M., Roelke, E., Gick, N., Choi, I., Edwards, S., Wasserman, E., Toufexis, D.J., Braas, K.M., et al. (2014). PACAP in the BNST produces anorexia and weight loss in male and female rats. Neuropsychopharmacology 39, 1614-1623. https://doi.org/10.1038/npp.2014.8
- Koob, G.F. (2003). Alcoholism, allostasis and beyond. Alcohol. Clin. Exp. Res. 27, 232-243. https://doi.org/10.1097/01.ALC.0000057122.36127.C2
- Koob, G.F. (2013). Addiction is a Reward Deficit and Stress Surfeit Disorder. Front Psychiatry 4, 72.
- Koob, G.F., and Le Moal, M. (2008). Review. Neurobiological mechanisms for opponent motivational processes in addiction. Philos. Trans. R Soc. Lond. B Biol. Sci. 363, 3113-3123. https://doi.org/10.1098/rstb.2008.0094
- Koster, A., Montkowski, A., Schulz, S., Stube, E.M., Knaudt, K., Jenck, F., Moreau, J.L., Nothacker, H.P., Civelli, O., and Reinscheid, R.K. (1999). Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice. Proc. Natl. Acad. Sci. USA 96, 10444-10449. https://doi.org/10.1073/pnas.96.18.10444
- Kotagale, N.R., Walke, S., Shelkar, G.P., Kokare, D.M., Umekar, M.J., and Taksande, B.G. (2014). Agmatine attenuates nicotine induced conditioned place preference in mice through modulation of neuropeptide Y system. Behav. Brain Res. 262, 118-124. https://doi.org/10.1016/j.bbr.2014.01.004
- Kozicz, T., Vigh, S., and Arimura, A. (1997). Axon terminals containing PACAP- and VIP-immunoreactivity form synapses with CRF-immunoreactive neurons in the dorsolateral division of the bed nucleus of the stria terminalis in the rat. Brain Res. 767, 109-119. https://doi.org/10.1016/S0006-8993(97)00737-3
- Kozicz, T., Vigh, S., and Arimura, A. (1998). The source of origin of PACAP- and VIP-immunoreactive fibers in the laterodorsal division of the bed nucleus of the stria terminalis in the rat. Brain Res. 810, 211-219. https://doi.org/10.1016/S0006-8993(98)00692-1
- Krawczyk, M., Mason, X., DeBacker, J., Sharma, R., Normandeau, C.P., Hawken, E.R., Di Prospero, C., Chiang, C., Martinez, A., Jones, A.A., et al. (2013). D1 dopamine receptor-mediated LTP at GABA synapses encodes motivation to self-administer cocaine in rats. J. Neurosci. 33, 11960-11971. https://doi.org/10.1523/JNEUROSCI.1784-13.2013
- Kuenzel, W.J., and McMurtry, J. (1988). Neuropeptide Y, brain localization and central effects on plasma insulin levels in chicks. Physiol. Behav. 44, 669-678. https://doi.org/10.1016/0031-9384(88)90334-4
- Lebow, M., Neufeld-Cohen, A., Kuperman, Y., Tsoory, M., Gil, S., and Chen, A. (2012). Susceptibility to PTSD-like behavior is mediated by corticotropin-releasing factor receptor type 2 levels in the bed nucleus of the stria terminalis. J. Neurosci. 32, 6906-6916. https://doi.org/10.1523/JNEUROSCI.4012-11.2012
- Lee, Y., Fitz, S., Johnson, P.L., and Shekhar, A. (2008). Repeated stimulation of CRF receptors in the BNST of rats selectively induces social but not panic-like anxiety. Neuropsychopharmacology 33, 2586-2594. https://doi.org/10.1038/sj.npp.1301674
- Lee, H.J., Macbeth, A.H., Pagani, J.H., and Young, W.S., 3rd. (2009). Oxytocin, the great facilitator of life. Prog. Neurobiol. 88, 127-151.
- Leinninger, G.M., Opland, D.M., Jo, Y.H., Faouzi, M., Christensen, L., Cappellucci, L.A., Rhodes, C.J., Gnegy, M.E., Becker, J.B., Pothos, E.N., et al. (2011). Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance. Cell Metabol. 14, 313-323. https://doi.org/10.1016/j.cmet.2011.06.016
- Leventhal, L., Mathis, J.P., Rossi, G.C., Pasternak, G.W., and Bodnar, R.J. (1998). Orphan opioid receptor antisense probes block orphanin FQ-induced hyperphagia. Eur. J. Pharmacol. 349, R1-3 https://doi.org/10.1016/S0014-2999(98)00272-6
- Lezak, K.R., Roelke, E., Harris, O.M., Choi, I., Edwards, S., Gick, N., Cocchiaro, G., Missig, G., Roman, C.W., Braas, K.M., et al. (2014a). Pituitary adenylate cyclase-activating polypeptide (PACAP) in the bed nucleus of the stria terminalis (BNST) increases corticosterone in male and female rats. Psychoneuroendocrinology 45, 11-20. https://doi.org/10.1016/j.psyneuen.2014.03.007
- Lezak, K.R., Roman, C.W., Braas, K.M., Schutz, K.C., Falls, W.A., Schulkin, J., May, V., and Hammack, S.E. (2014b). Regulation of bed nucleus of the stria terminalis PACAP expression by stress and corticosterone. J. Mol. Neurosci. 54, 477-484.. https://doi.org/10.1007/s12031-014-0269-8
- Li, C., Pleil, K.E., Stamatakis, A.M., Busan, S., Vong, L., Lowell, B.B., Stuber, G.D., and Kash, T.L. (2012). Presynaptic inhibition of gamma-aminobutyric acid release in the bed nucleus of the stria terminalis by kappa opioid receptor signaling. Biol. Psychiatry 71, 725-732. https://doi.org/10.1016/j.biopsych.2011.11.015
- Li, Y., Dong, X., Li, S., and Kirouac, G.J. (2014). Lesions of the posterior paraventricular nucleus of the thalamus attenuate fear expression. Front. Behav. Neurosci. 8, 94.
- Liang, K.C., Chen, H.C., and Chen, D.Y. (2001). Posttraining infusion of norepinephrine and corticotrophin releasing factor into the bed nucleus of the stria terminalis enhanced retention in an inhibitory avoidance task. Chin. J. Physiol. 44, 33-43.
- Lopez, M.F., Griffin, W.C.3rd., Melendez, R.I., and Becker, H.C. (2012). Repeated cycles of chronic intermittent ethanol exposure leads to the development of tolerance to aversive effects of ethanol in C57BL/6J mice. Alcohol. Clin. Exp. Res. 36, 1180-1187. https://doi.org/10.1111/j.1530-0277.2011.01717.x
- Lovejoy, D.A., and Balment, R.J. (1999). Evolution and physiology of the corticotrophin-releasing factor (CRF) family of neuropeptides in vertebrates. Gen. Comp. Endocrinol. 115, 1-22.
- Lowery-Gionta, E.G., Marcinkiewcz, C.A., and Kash, T.L. (2014). Functional alterations in the dorsal raphe nucleus following acute and chronic ethanol exposure. Neuropsychopharmacology [Epub ahead of print].
- Lutz, E.M., Sheward, W.J., West, K.M., Morrow, J.A., Fink, G., and Harmar, A.J. (1993). The VIP2 receptor, molecular characterisation of a cDNA encoding a novel receptor for vasoactive intestinal peptide. FEBS Lett. 334, 3-8. https://doi.org/10.1016/0014-5793(93)81668-P
- Marchant, N.J., Densmore, V.S., and Osborne, P.B. (2007). Coexpression of prodynorphin and corticotrophin-releasing hormone in the rat central amygdala, evidence of two distinct endogenous opioid systems in the lateral division. J. Comp. Neurol. 504, 702-715. https://doi.org/10.1002/cne.21464
- Martinez, L.A., Albers, H.E., and Petrulis, A. (2010). Blocking oxytocin receptors inhibits vaginal marking to male odors in female Syrian hamsters. Physiol. Behav. 101, 685-692. https://doi.org/10.1016/j.physbeh.2010.08.007
- Martinez, L.A., Levy, M.J., and Petrulis, A. (2013). Endogenous oxytocin is necessary for preferential Fos expression to male odors in the bed nucleus of the stria terminalis in female Syrian hamsters. Horm. Behav. 64, 653-664. https://doi.org/10.1016/j.yhbeh.2013.08.016
- Matsushita, H., Ishihara, A., Mashiko, S., Tanaka, T., Kanno, T., Iwaasa, H., Ohta, H., and Kanatani, A. (2009). Chronic intracerebroventricular infusion of nociceptin/orphanin FQ produces body weight gain by affecting both feeding and energy metabolism in mice. Endocrinology 150, 2668-2673. https://doi.org/10.1210/en.2008-1515
- Matzeu, A., Zamora-Martinez, E.R., and Martin-Fardon, R. (2014). The paraventricular nucleus of the thalamus is recruited by both natural rewards and drugs of abuse, recent evidence of a pivotal role for orexin/hypocretin signaling in this thalamic nucleus in drug-seeking behavior. Front. Behav. Neurosci. 8, 117.
- McDonald, A.J. (1989). Coexistence of somatostatin with neuropeptide Y, but not with cholecystokinin or vasoactive intestinal peptide, in neurons of the rat amygdala. Brain Res. 500, 37-45. https://doi.org/10.1016/0006-8993(89)90297-7
- McElligott, Z.A., Fox ME, Walsh PL, Urban DJ, Ferrel MS, Roth BL, and Wightman RM. (2013). Noradrenergic synaptic function in the bed nucleus of the stria terminalis varies in animal models of anxiety and addiction. Neuropsychopharmacology 38, 1665-1673. https://doi.org/10.1038/npp.2013.63
- McReynolds, J.R., Vranjkovic O, Thao M, Baker DA, Makky K, Lim Y, and Mantsch JR. (2014). Beta-2 adrenergic receptors mediate stress-evoked reinstatement of cocaine-induced conditioned place preference and increases in CRF mRNA in the bed nucleus of the stria terminalis in mice. Psychopharmacology 231, 3953-3963. https://doi.org/10.1007/s00213-014-3535-0
- Meloni, E.G., Gerety, L.P., Knoll, A.T., Cohen, B.M., and Carlezon, W.A. (2006). Behavioral and anatomical interactions between dopamine and corticotrophin-releasing factor in the rat. J. Neurosci. 26, 3855-3863. https://doi.org/10.1523/JNEUROSCI.4957-05.2006
- Micioni, D.i. Bonaventura, M.V., Ciccocioppo, R., Romano, A., Bossert, J.M., Rice, K.C., Ubaldi, M., St Laurent, R., Gaetani, S., Massi, M., et al. (2014). Role of bed nucleus of the stria terminalis corticotrophin-releasing factor receptors in frustration stress-induced binge-like palatable food consumption in female rats with a history of food restriction. J. Neurosci. 34, 11316-11324. https://doi.org/10.1523/JNEUROSCI.1854-14.2014
- Miyata, A., Arimura, A., Dahl, R.R., Minamino, N., Uehara, A., Jiang, L., Culler, M.D., and Coy, D.H. (1989). Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells. Biochem. Biophys. Res. Commun. 164, 567-574. https://doi.org/10.1016/0006-291X(89)91757-9
- Miyata, A., Jiang, L., Dahl, R.D., Kitada, C., Kubo, K., Fujino, M., Minamino, N., and Arimura, A. (1990). Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38). Biochem. Biophys. Res. Commun. 170, 643-648. https://doi.org/10.1016/0006-291X(90)92140-U
- Moga, M.M., and Gray, T.S. (1985a). Evidence for corticotropinreleasing factor, neurotensin, and somatostatin in the neural pathway from the central nucleus of the amygdala to the parabrachial nucleus. J. Comp. Neurol. 241, 275-284. https://doi.org/10.1002/cne.902410304
- Moga, M.M., and Gray, T.S. (1985b). Peptidergic efferents from the intercalated nuclei of the amygdala to the parabrachial nucleus in the rat. Neurosci. Lett. 61, 13-18. https://doi.org/10.1016/0304-3940(85)90393-3
- Moga, M.M, Saper, C.B, and Gray, T.S. (1989). Bed nucleus of the stria terminalis, cytoarchitecture, immunohistochemistry, and projection to the parabrachial nucleus in the rat. J. Comp. Neurol. 283, 315-332. https://doi.org/10.1002/cne.902830302
- Mollereau, C., Simons, M.J., Soularue, P., Liners, F., Vassart, G., Meunier, J.C., and Parmentier, M. (1996). Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene. Proc. Natl. Acad. Sci. USA 93, 8666-8670. https://doi.org/10.1073/pnas.93.16.8666
- Morin, S.M., Ling, N., Liu, X.J., Kahl, S.D., and Gehlert, D.R. (1999). Differential distribution of urocortin- and corticotrophin-releasing factor-like immunoreactivities in the rat brain. Neuroscience 92, 281-291. https://doi.org/10.1016/S0306-4522(98)00732-5
- Myers, E.A., Banihashemi, L., and Rinaman, L. (2005). The anxiogenic drug yohimbine activates central viscerosensory circuits in rats. J. Comp. Neurol. 492, 426-441. https://doi.org/10.1002/cne.20727
- Nader, J., Chauvet, C., Rawas, R.E., Favot, L., Jaber, M., Thiriet, N., and Solinas, M. (2012). Loss of environmental enrichment increases vulnerability to cocaine addiction. Neuropsychopharmacology 37, 1579-1587. https://doi.org/10.1038/npp.2012.2
- Nagai, M.M., Gomes, F.V., Crestani, C.C., Resstel, L.B., and Joca, S.R. (2013). Noradrenergic neurotransmission within the bed nucleus of the stria terminalis modulates the retention of immobility in the rat forced swimming test. Behav. Pharmacol. 24, 214-221. https://doi.org/10.1097/FBP.0b013e3283618ae4
- Neal, C.R.Jr., Swann, J.M., and Newman, S.W. (1989). The colocalization of substance P and prodynorphin immunoreactivity in neurons of the medial preoptic area, bed nucleus of the stria terminalis and medial nucleus of the amygdala of the Syrian hamster. Brain Res. 496, 1-13 https://doi.org/10.1016/0006-8993(89)91046-9
- Neal, C.R., Mansour, A., Reinscheid, R., Nothacker, H.P., Civelli, O., and Watson, S.J. (1999). Localization of orphanin FQ (nociceptin) peptide and messenger RNA in the central nervous system of the rat. J. Comp. Neurol. 406, 503-547. https://doi.org/10.1002/(SICI)1096-9861(19990419)406:4<503::AID-CNE7>3.0.CO;2-P
- Nilsson, I., Johansen, J.E., Schalling, M., Hokfelt, T., and Fetissov, S.O. (2005). Maturation of the hypothalamic arcuate agoutirelated protein system during postnatal development in the mouse. Brain Res. Dev. Brain Res. 155, 147-154. https://doi.org/10.1016/j.devbrainres.2005.01.009
-
Nobis, W.P., Kash, T.L., Silberman, Y., and Winder, D.G. (2011).
$\beta$ - Adrenergic receptors enhance excitatory transmission in the bed nucleus of the stria terminalis through a corticotrophin-releasing factor receptor-dependent and cocaine-regulated mechanism. Biol. Psychiat. 69, 1083-1090. https://doi.org/10.1016/j.biopsych.2010.12.030 - O'Donohue, T.L., Chronwall, B.M., Pruss, R.M., Mezey, E., Kiss, J.Z., Eiden, L.E., Massari, V.J, Tessel, R.E, Pickel, V.M., DiMaggio, D.A., et al. (1985). Neuropeptide Y and peptide YY neuronal and endocrine systems. Peptides 6, 755-768. https://doi.org/10.1016/0196-9781(85)90180-9
- Ogi, K., Kimura, C., Onda, H., Arimura, A., and Fujino, M. (1990). Molecular cloning and characterization of cDNA for the precursor of rat pituitary adenylate cyclase activating polypeptide (PACAP). Biochem. Biophys. Res. Commun. 173, 1271-1279. https://doi.org/10.1016/S0006-291X(05)80924-6
- Ohata, H., and Shibasaki, T. (2011). Involvement of CRF2 receptor in the brain regions in restraint-induced anorexia. Neuroreport 22, 494-498. https://doi.org/10.1097/WNR.0b013e3283487467
- Olive, M.F., Koenig, H.N., Nannini, M.A., and Hodge, C.W. (2002). Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake. Pharmacol. Biochem. Behav. 72, 213-220. https://doi.org/10.1016/S0091-3057(01)00748-1
- Otto, C., Martin, M., Wolfer, D.P., Lipp, H.P., Maldonado, R., and Schutz, G. (2001). Altered emotional behavior in PACAP-type-Ireceptor- deficient mice. Brain Res. Mol. Brain Res. 92, 78-84. https://doi.org/10.1016/S0169-328X(01)00153-X
- Overstreet, D.H., Knapp, D.J., Moy, S.S., and Breese, G.R. (2003). A 5-HT1A agonist and a 5-HT2c antagonist reduce social interaction deficit induced by multiple ethanol withdrawals in rats. Psychopharmacology 167, 344-352. https://doi.org/10.1007/s00213-003-1425-y
- Palkovits, M., Somogyvari-Vigh, A., and Arimura, A. (1995). Concentrations of pituitary adenylate cyclase activating polypeptide (PACAP) in human brain nuclei. Brain Res. 699, 116-120. https://doi.org/10.1016/0006-8993(95)00869-R
- Pandey, S.C., Carr, L.G., Heilig, M., Ilveskoski, E., and Thiele, T.E. (2003). Neuropeptide y and alcoholism, genetic, molecular, and pharmacological evidence. Alcohol. Clin. Exp. Res. 27, 149-154. https://doi.org/10.1097/01.ALC.0000052706.21367.0E
- Patki, G., Solanki, N., Atrooz, F., Ansari, A., Allam, F., Jannise, B., Maturi, J., and Salim, S. (2014). Novel mechanistic insights into treadmill exercise based rescue of social defeat-induced anxiety-like behavior and memory impairment in rats. Physiol. Behav. 130, 135-144. https://doi.org/10.1016/j.physbeh.2014.04.011
- Peyron, C., Tighe, D.K., van den Pol, A.N., de Lecea, L., Heller, H.C., Sutcliffe, J.G., and Kilduff, T.S. (1998). Neurons containing hypocretin (orexin) project to multiple neuronal systems. J. Neurosci. 18, 9996-10015
- Phelix, C.F., Liposits, Z., and Paull, W.K. (1992). Monoamine innervation of the bed nucleus of stria terminalis, an electron microscopic investigation. Brain Res. Bull. 28, 949-965. https://doi.org/10.1016/0361-9230(92)90218-M
- Piggins, H.D., Stamp, J.A., Burns, J., Rusak, B., and Semba, K. (1996). Distribution of pituitary adenylate cyclase activating polypeptide (PACAP) immunoreactivity in the hypothalamus and extended amygdala of the rat. J. Comp. Neurol. 376, 278-294. https://doi.org/10.1002/(SICI)1096-9861(19961209)376:2<278::AID-CNE9>3.0.CO;2-0
- Pisegna, J.R., and Wank, S.A. (1993). Molecular cloning and functional expression of the pituitary adenylate cyclase-activating polypeptide type I receptor. Proc. Natl. Acad. Sci. USA 90, 6345-6349. https://doi.org/10.1073/pnas.90.13.6345
- Pleil, K.E., Lopez, A., McCall, N., Jijon, A.M., Bravo, J.P., and Kash, T.L. (2012). Chronic stress alters neuropeptide Y signaling in the bed nucleus of the stria terminalis in DBA/2J but not C57BL/6J mice. Neuropharmacology 62, 1777-1786. https://doi.org/10.1016/j.neuropharm.2011.12.002
- Polidori, C., de Caro, G., and Massi, M. (2000). The hyperphagic effect of nociceptin/orphanin FQ in rats. Peptides 21, 1051-162. https://doi.org/10.1016/S0196-9781(00)00243-6
- Pomonis, J.D., Billington, C.J., and Levine, A.S. (1996). Orphanin FQ, agonist of orphan opioid receptor ORL1, stimulates feeding in rats. Neuroreport 8, 369-371. https://doi.org/10.1097/00001756-199612200-00072
- Pompolo, S., Ischenko, O., Pereira, A., Iqbal, J., and Clarke, I.J. (2005). Evidence that projections from the bed nucleus of the stria terminalis and from the lateral and medial regions of the preoptic area provide input to gonadotropin releasing hormone (GNRH) neurons in the female sheep brain. Neuroscience 132, 421-436. https://doi.org/10.1016/j.neuroscience.2004.12.042
- Poulin, J.F., Arbour, D., Laforest, S., and Drolet, G. (2009). Neuroanatomical characterization of endogenous opioids in the bed nucleus of the stria terminalis. Prog. Neuropsychopharmacol. Biol. Psychiatry 33, 1356-1365. https://doi.org/10.1016/j.pnpbp.2009.06.021
- Rangani, R.J., Upadhya, M.A., Nakhate, K.T., Kokare, D.M., and Subhedar, N.K. (2012). Nicotine evoked improvement in learning and memory is mediated through NPY Y1 receptors in rat model of Alzheimer's disease. Peptides 33, 317-328. https://doi.org/10.1016/j.peptides.2012.01.004
- Ravinder, S., Burghardt, N.S., Brodsky, R., Bauer, E.P., and Chattarji, S. (2013). A role for the extended amygdala in the fear-enhancing effects of acute selective serotonin reuptake inhibitor treatment. Transl. Psychiatry 3, e209. https://doi.org/10.1038/tp.2012.137
- Reinscheid, R.K., Nothacker, H.P., Bourson, A., Ardati, A., Henningsen, R.A., Bunzow, J.R., Grandy, D.K., Langen, H., Monsma, F.J., and Civelli, O. (1995). Orphanin FQ, a neuropeptide that activates an opioidlike G protein-coupled receptor. Science 270, 792-794. https://doi.org/10.1126/science.270.5237.792
- Ressler, K.J., Mercer, K.B., Bradley, B., Jovanovic, T., Mahan, A., Kerley, K., Norrholm, S.D., Kilaru, V., Smith, A.K., Myers, A.J., et al. (2011). Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor. Nature 470, 492-497. https://doi.org/10.1038/nature09856
- Reul, J.M., and Holsboer, F. (2002). On the role of corticotropinreleasing hormone receptors in anxiety and depression. Dialogues Clin. Neurosci. 4, 31-46.
- Reuss, S., and Olcese, J. (1995). Neuropeptide Y, distribution of immunoreactivity and quantitative analysis in diencephalic structures and cerebral cortex of dwarf hamsters under different photoperiods. Neuroendocrinology 61, 337-347. https://doi.org/10.1159/000126856
- Reuss, S., Hurlbut, E.C., Speh, J.C., and Moore, R.Y. (1990). Neuropeptide Y localization in telencephalic and diencephalic structures of the ground squirrel brain. Am. J. Anat. 188, 163-174. https://doi.org/10.1002/aja.1001880206
- Robles, C.F., McMackin, M.Z., Campi, K.L., Doig, I.E., Takahashi, E.Y., Pride, M.C., and Trainor, B.C. (2014). Effects of kappa opioid receptors on conditioned place aversion and social interaction in males and females. Behav. Brain Res. 262, 84-93. https://doi.org/10.1016/j.bbr.2014.01.003
- Rodi, D., Zucchini, S., Simonato, M., Cifani, C., Massi, M., and Polidori, C. (2007). Functional antagonism between nociceptin/ orphanin FQ (N/OFQ) and corticotropin-releasing factor (CRF) in the rat brain, evidence for involvement of the bed nucleus of the stria terminalis. Psychopharmacology 196, 523-531.
- Roman, C.W., Lezak, K.R., Hartsock, M.J., Falls, W.A., Braas, K.M., Howard, A.B., Hammack, S.E., and May, V. (2014). PAC1 receptor antagonism in the bed nucleus of the stria terminalis (BNST) attenuates the endocrine and behavioral consequences of chronic stress. Psychoneuroendocrinology 47, 151-165. https://doi.org/10.1016/j.psyneuen.2014.05.014
- Roy, A., and Pandey, S.C. (2002). The decreased cellular expression of neuropeptide Y protein in rat brain structures during ethanol withdrawal after chronic ethanol exposure. Alcohol Clin. Exp. Res. 26, 796-803. https://doi.org/10.1111/j.1530-0277.2002.tb02607.x
- Russell, S.E., Rachlin, A.B., Smith, K.L., Muschamp, J., Berry, L., Zhao, Z., and Chartoff, E.H. (2014). Sex differences in sensitivity to the depressive-like effects of the kappa opioid receptor agonist U-50488 in rats. Biol. Psychiatry 76, 213-222. https://doi.org/10.1016/j.biopsych.2013.07.042
- Rygula, R., Abumaria, N., Flugge, G., Fuchs, E., Ruther, E., and Havemann-Reinecke, U. (2005). Anhedonia and motivational deficits in rats, impact of chronic social stress. Behav. Brain Res. 162, 127-134. https://doi.org/10.1016/j.bbr.2005.03.009
- Rygula, R., Abumaria, N., Domenici, E., Hiemke, C., and Fuchs, E. (2006). Effects of fluoxetine on behavioral deficits evoked by chronic social stress in rat. Behav. Brain Res. 174, 188-192. https://doi.org/10.1016/j.bbr.2006.07.017
- Sahuque, L.L., Kullberg, E.F., McGeehan, A.J., Kinder, J.R., Hicks, M.P., Blanton, M.G., Janak, P.H., and Olive, M.F. (2006). Anxiogenic and aversive effects of corticotrophin-releasing factor (CRF) in the bed nucleus of stria terminalis in the rat, role of CRF receptor subtypes. Psychopharmacology 186, 122-132. https://doi.org/10.1007/s00213-006-0362-y
- Sakanaka, M., Shibasaki, T., and Lederis, K. (1986). Distribution and efferent projections of corticotrophin-releasing factor-like immunoreactivity in the rat amygdaloid complex. Brain Res. 382, 213-238. https://doi.org/10.1016/0006-8993(86)91332-6
- Schafer, E.A., and Mackenzie, K. (1911). The Action of Animal Extracts on Milk Secretion. Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character 84, 16-22. https://doi.org/10.1098/rspb.1911.0042
- Shen, C.L. (1987). Distribution of neuropeptide Y immunoreactivity in the forebrain of the rat. Proc. Natl. Sci. Counc. Repub. China B 11, 115-127.
- Sheward, W.J., Lutz, E.M., and Harmar, A.J. (1995). The distribution of vasoactive intestinal peptide2 receptor messenger RNA in the rat brain and pituitary gland as assessed by in situ hybridization. Neuroscience 67, 409-418. https://doi.org/10.1016/0306-4522(95)00048-N
- Shin, J.W., Geerling, J.C., and Loewy, A.D. (2008). Inputs to the ventrolateral bed nucleus of the stria terminalis. J. Comp. Neurol. 511, 628-657. https://doi.org/10.1002/cne.21870
- Silberman, Y., Matthews, R.T., and Winder, D.G. (2013). A corticotrophin releasing factor pathway for ethanol regulation of the ventral tegmental area in the bed nucleus of stria terminalis. J. Neurosci. 33, 950-960. https://doi.org/10.1523/JNEUROSCI.2949-12.2013
- Sink, K.S., Walker, D.L., Freeman, S.M., Flandreau, E.I., Ressler, K.J., and Davis, M. (2013). Effects of continuously enhanced corticotrophin releasing factor expression within the bed nucleus of the stria terminalis on conditioned and unconditioned anxiety. Mol. Psychiatr. 18, 308-319. https://doi.org/10.1038/mp.2011.188
- Slawecki, C.J., Somes, C., and Ehlers, C.L. (1999). Effects of chronic ethanol exposure on neurophysiological responses to corticotropin-releasing factor and neuropeptide Y. Alcohol. Alcohol. 34, 289-299. https://doi.org/10.1093/alcalc/34.3.289
- Smith, Y., Parent, A., Kerkerian, L., and Pelletier, G. (1985). Distribution of neuropeptide Y immunoreactivity in the basal forebrain and upper brainstem of the squirrel monkey (Saimiri sciureus). J. Comp. Neurol. 236, 71-89. https://doi.org/10.1002/cne.902360107
- Sparrow, A.M., Lowery-Gionta, E.G., Pleil, K.E., Li, C., Sprow, G.M., Cox, B.R, Rinker, J.A., Jijon, A.M., Pena, J., Navarro, M., et al. (2012). Central neuropeptide Y modulates binge-like ethanol drinking in C57BL/6J mice via Y1 and Y2 receptors. Neuropsychopharmacology 37, 1409-1421. https://doi.org/10.1038/npp.2011.327
- Spengler, D., Waeber, C., Pantaloni, C., Holsboer, F., Bockaert, J., Seeburg, P.H., and Journot, L. (1993). Differential signal transduction by five splice variants of the PACAP receptor. Nature 365, 170-175. https://doi.org/10.1038/365170a0
- Stroth, N., Holighaus, Y., Ait-Ali, D., and Eiden, L.E. (2011). PACAP, a master regulator of neuroendocrine stress circuits and the cellular stress response. Ann. N Y Acad. Sci. 1220, 49-59. https://doi.org/10.1111/j.1749-6632.2011.05904.x
- Sullivan, G.M., Apergis, J., Bush, D.E., Johnson, L.R., Hou, M., and Ledoux, J.E. (2004). Lesions in the bed nucleus of the stria terminalis disrupt corticosterone and freezing responses elicited by a contextual but not by a specific cue-conditioned fear stimulus. Neuroscience 128, 7-14. https://doi.org/10.1016/j.neuroscience.2004.06.015
- Szucs, A., Berton, F., Sanna, P.P., and Francesconi, W. (2012). Excitability of jcBNST neurons is reduced in alcohol-dependent animals during protracted alcohol withdrawal. PLoS One 7, e42313. https://doi.org/10.1371/journal.pone.0042313
- Takagishi, M., and Chiba, T. (1991). Efferent projections of the infralimbic (area 25) region of the medial prefrontal cortex in the rat, an anterograde tracer PHA-L study. Brain Res. 566, 26-39. https://doi.org/10.1016/0006-8993(91)91677-S
- Takahashi, L.K. (2001). Role of CRF(1) and CRF(2) receptors in fear and anxiety. Neurosci. Biobehav. Rev. 25, 627-636. https://doi.org/10.1016/S0149-7634(01)00046-X
- Tasan, R.O., Nguyen, N.K., Weger, S., Sartori, S.B., Singewald, N., Heilbronn, R., Herzog, H., and Sperk, G. (2010). The central and basolateral amygdala are critical sites of neuropeptide Y/Y2 receptor-mediated regulation of anxiety and depression. J. Neurosci. 30, 6282-6290. https://doi.org/10.1523/JNEUROSCI.0430-10.2010
- Tran, L., Schulkin, J., and Greenwood-Van Meerveld, B. (2014). Importance of CRF receptor-mediated mechanisms of the bed nucleus of the stria terminalis in the processing of anxiety and pain. Neuropsychopharmacology 39, 2633-2645. https://doi.org/10.1038/npp.2014.117
- Uddin, M., Chang, S.C., Zhang, C., Ressler, K., Mercer, K.B., Galea, S., Keyes, K.M., McLaughlin, K.A., Wildman, D.E., Aiello, A.E., et al. (2013). Adcyap1r1 genotype, posttraumatic stress disorder, and depression among women exposed to childhood maltreatment. Depress Anxiety 30, 251-258. https://doi.org/10.1002/da.22037
- van den Pol, A.N. (2012). Neuropeptide transmission in brain circuits. Neuron 76, 98-115. https://doi.org/10.1016/j.neuron.2012.09.014
- Varty, G.B., Lu, S.X., Morgan, C.A., Cohen-Williams, M.E., Hodgson, R.A., Smith-Torhan, A., Zhang, H., Fawzi, A.B., Graziano, M.P., Ho, G.D., et al. (2008). The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8- [bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1] octan-3- ol (SCH 221510). J. Pharmacol. Exp. Ther. 326, 672-682. https://doi.org/10.1124/jpet.108.136937
- Vaudry, D., Falluel-Morel, A., Bourgault, S., Basille, M., Burel, D., Wurtz, O., Fournier, A., Chow, B.K., Hashimoto, H., Galas, L., et al. (2009). Pituitary adenylate cyclase-activating polypeptide and its receptors, 20 years after the discovery. Pharmacol. Rev. 61, 283-357. https://doi.org/10.1124/pr.109.001370
- Vertes, R.P. (2004). Differential projections of the infralimbic and prelimbic cortex in the rat. Synapse 51, 32-58. https://doi.org/10.1002/syn.10279
- Walker, D.L., and Davis, M. (1997). Double dissociation between the involvement of the bed nucleus of the stria terminalis and the central nucleus of the amygdala in startle increases produced by conditioned versus unconditioned fear. J. Neurosci. 17, 9375-9383.
- Walker, D.L., Miles, L.A., and Davis, M. (2009a). Selective participation of the bed nucleus of the stria terminalis and CRF in sustained anxiety-like versus phasic fear-like responses. Prog. Neuropsychopharmacol. Biol. Psychiatry 33, 1291-1308. https://doi.org/10.1016/j.pnpbp.2009.06.022
- Walker, D.L., Yang, Y., Ratti, E., Corsi, M., Trist, D., and Davis, M. (2009b). Differential effects of the CRF-R1 antagonist GSK876008 on fear-potentiated, light- and CRF-enhanced startle suggest preferential involvement in sustained vs phasic threat responses. Neuropsychopharmacology 34, 1533-1542. https://doi.org/10.1038/npp.2008.210
- Walter, A., Mai, J.K., Lanta, L., and Gorcs, T. (1991). Differential distribution of immunohistochemical markers in the bed nucleus of the stria terminalis in the human brain. J. Chem. Neuroanat. 4, 281-298. https://doi.org/10.1016/0891-0618(91)90019-9
- Wang, J., Fang, Q., Liu, Z., and Lu, L. (2006). Region-specific effects of brain corticotropin-releasing factor receptor type 1 blockade on footshock-stress- or drug-priming-induced reinstatement of morphine conditioned place preference in rats. Psychopharmacology 185, 19-28. https://doi.org/10.1007/s00213-005-0262-6
- Wang, L., Cao, C., Wang, R., Qing, Y., Zhang, J., and Zhang, X.Y. (2013). PAC1 receptor (ADCYAP1R1) genotype is associated with PTSD's emotional numbing symptoms in Chinese earthquake survivors. J. Affect Disord. 150, 156-159. https://doi.org/10.1016/j.jad.2013.01.010
- Weinberg, D.H., Sirinathsinghji, D.J., Tan, C.P., Shiao, L.L., Morin, N., Rigby, M.R., Heavens, R.H., Rapoport, D.R., Bayne, M.L., Cascieri, M.A., et al. (1996). Cloning and expression of a novel neuropeptide Y receptor. J. Biol. Chem. 271, 16435-16438. https://doi.org/10.1074/jbc.271.28.16435
- Wenzel, J.M., Cotton, S.W., Dominguez, H.M., Lane, J.E., Shelton, K., Su, Z.I., and Ettenberg, A. (2014). Noradrenergic beta-receptor antagonism within the central nucleus of the amygdala or bed nucleus of the stria terminalis attenuates the negative/anxiogenic effects of cocaine. J. Neurosci. 34, 3467-34674. https://doi.org/10.1523/JNEUROSCI.3861-13.2014
- Wills, T.A., Klug, J.R., Silberman, Y., Baucum, A.J., Weitlauf, C., Colbran, R.J., Delpire, E., and Winder, D.G. (2012). GluN2B subunit deletion reveals key role in acute and chronic ethanol sensitivity of glutamate synapses in bed nucleus of the stria terminalis. Proc. Natl. Acad. Sci. USA 109, E278-287. https://doi.org/10.1073/pnas.1113820109
Cited by
- Diet-Induced Obesity and Circadian Disruption of Feeding Behavior vol.11, 2017, https://doi.org/10.3389/fnins.2017.00023
- Epigenetic impacts of endocrine disruptors in the brain vol.44, 2017, https://doi.org/10.1016/j.yfrne.2016.09.002
- Pharmacology of the Bed Nucleus of the Stria Terminalis vol.2, pp.6, 2016, https://doi.org/10.1007/s40495-016-0077-7
- Overshadowed by the amygdala: the bed nucleus of the stria terminalis emerges as key to psychiatric disorders vol.21, pp.4, 2016, https://doi.org/10.1038/mp.2016.1
- Ventral Tegmental Area Afferents and Drug-Dependent Behaviors vol.7, 2016, https://doi.org/10.3389/fpsyt.2016.00030
- Contrasting Regulation of Catecholamine Neurotransmission in the Behaving Brain: Pharmacological Insights from an Electrochemical Perspective vol.69, pp.1, 2017, https://doi.org/10.1124/pr.116.012948
- Role of the bed nucleus of the stria terminalis in aversive learning and memory vol.24, pp.9, 2017, https://doi.org/10.1101/lm.044206.116
- The bed nucleus of the stria terminalis in drug-associated behavior and affect: A circuit-based perspective vol.122, 2017, https://doi.org/10.1016/j.neuropharm.2017.03.028
- Acute engagement of Gq-mediated signaling in the bed nucleus of the stria terminalis induces anxiety-like behavior 2016, https://doi.org/10.1038/mp.2016.218
- Insights into the central pathways involved in the emetic and behavioural responses to exendin-4 in the ferret vol.202, 2017, https://doi.org/10.1016/j.autneu.2016.09.003
- Dissociation in control of physiological and behavioral responses to emotional stress by cholinergic neurotransmission in the bed nucleus of the stria terminalis in rats vol.101, 2016, https://doi.org/10.1016/j.neuropharm.2015.10.018
- Effects of chronic alcohol consumption on neuronal function in the non-human primate BNST vol.21, pp.6, 2016, https://doi.org/10.1111/adb.12289
- Oxytocin receptor neurotransmission in the dorsolateral bed nucleus of the stria terminalis facilitates the acquisition of cued fear in the fear-potentiated startle paradigm in rats vol.121, 2017, https://doi.org/10.1016/j.neuropharm.2017.04.039
- Effects of chronic ethanol exposure on neuronal function in the prefrontal cortex and extended amygdala vol.99, 2015, https://doi.org/10.1016/j.neuropharm.2015.06.017
- Optogenetic study of the projections from the bed nucleus of the stria terminalis to the central amygdala vol.114, pp.5, 2015, https://doi.org/10.1152/jn.00677.2015
- Unravelling the role and mechanism of adipokine and gastrointestinal signals in animal models in the nonhomeostatic control of energy homeostasis: Implications for binge eating disorder pp.10724133, 2018, https://doi.org/10.1002/erv.2641
- Reversible Inactivation of the Bed Nucleus of the Stria Terminalis Prevents Reinstatement But Not Renewal of Extinguished Fear , , vol.2, pp.3, 2015, https://doi.org/10.1523/eneuro.0037-15.2015
- PAC1 receptor ( ADCYAP1R1 ) genotype and problematic alcohol use in a sample of young women vol.13, pp.None, 2015, https://doi.org/10.2147/ndt.s137331
- GLP-1 action in the mouse bed nucleus of the stria terminalis vol.131, pp.None, 2018, https://doi.org/10.1016/j.neuropharm.2017.12.007
- Anterior cingulate cortex connectivity is associated with suppression of behaviour in a rat model of chronic pain vol.2, pp.None, 2015, https://doi.org/10.1177/2398212818779646
- Brain region-dependent gene networks associated with selective breeding for increased voluntary wheel-running behavior vol.13, pp.8, 2015, https://doi.org/10.1371/journal.pone.0201773
- Synaptic Plasticity in the Bed Nucleus of the Stria Terminalis: Underlying Mechanisms and Potential Ramifications for Reinstatement of Drug- and Alcohol-Seeking Behaviors vol.9, pp.9, 2015, https://doi.org/10.1021/acschemneuro.8b00169
- Sex-Dependent Effects of Mild Blast-induced Traumatic Brain Injury on Corticotropin-releasing Factor Receptor Gene Expression: Potential Link to Anxiety-like Behaviors vol.392, pp.None, 2015, https://doi.org/10.1016/j.neuroscience.2018.09.014
- Neuropeptidergic Control of an Internal Brain State Produced by Prolonged Social Isolation Stress vol.83, pp.None, 2018, https://doi.org/10.1101/sqb.2018.83.038109
- Role of the Bed Nucleus of the Stria Terminalis in PTSD: Insights From Preclinical Models vol.13, pp.None, 2019, https://doi.org/10.3389/fnbeh.2019.00068
- New Frontiers in Anxiety Research: The Translational Potential of the Bed Nucleus of the Stria Terminalis vol.10, pp.None, 2015, https://doi.org/10.3389/fpsyt.2019.00510
- The first identification of nesfatin-1-expressing neurons in the human bed nucleus of the stria terminalis vol.126, pp.3, 2015, https://doi.org/10.1007/s00702-019-01984-3
- Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats vol.10, pp.1, 2015, https://doi.org/10.1038/s41467-019-09183-0
- Turning the ′Tides on Neuropsychiatric Diseases: The Role of Peptides in the Prefrontal Cortex vol.14, pp.None, 2020, https://doi.org/10.3389/fnbeh.2020.588400
- Dynorphin and its role in alcohol use disorder vol.1735, pp.None, 2020, https://doi.org/10.1016/j.brainres.2020.146742
- Corticotropin Releasing Hormone Signaling in the Bed Nuclei of the Stria Terminalis as a Link to Maladaptive Behaviors vol.15, pp.None, 2021, https://doi.org/10.3389/fnins.2021.642379
- Extended Amygdala Neuropeptide Circuitry of Emotional Arousal: Waking Up on the Wrong Side of the Bed Nuclei of Stria Terminalis vol.15, pp.None, 2021, https://doi.org/10.3389/fnbeh.2021.613025
- Pituitary adenylate cyclase-activating polypeptide (PACAP) modulates dependence-induced alcohol drinking and anxiety-like behavior in male rats vol.46, pp.3, 2021, https://doi.org/10.1038/s41386-020-00904-4
- Functional Dissection of Glutamatergic and GABAergic Neurons in the Bed Nucleus of the Stria Terminalis vol.44, pp.2, 2015, https://doi.org/10.14348/molcells.2021.0006