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Effects of NecroX-5 on the Survival of a Random Pattern Skin Flap in Mice

  • Kang, Dai Hun (Department of Plastic and Reconstructive Surgery, Yeungnam University Medical Center, Yeungnam University College of Medicine) ;
  • Kim, Yong-Ha (Department of Plastic and Reconstructive Surgery, Yeungnam University Medical Center, Yeungnam University College of Medicine) ;
  • Kim, Moon Kyu (Department of Immnunology, Kyungpook National University School of Medicine) ;
  • Kim, Mi Sun (Department of Immnunology, Kyungpook National University School of Medicine) ;
  • Chung, Kyu-Jin (Department of Plastic and Reconstructive Surgery, Yeungnam University Medical Center, Yeungnam University College of Medicine)
  • Received : 2015.05.08
  • Accepted : 2015.09.14
  • Published : 2015.11.15

Abstract

Keywords

References

  1. Esteves Junior I, Masson IB, Oshima CT, et al. Low-level laser irradiation, cyclooxygenase-2 (COX-2) expression and necrosis of random skin flaps in rats. Lasers Med Sci 2012;27:655-60. https://doi.org/10.1007/s10103-011-1011-1
  2. Baris R, Kankaya Y, Ozer K, et al. The effect of microneedling with a roller device on the viability of random skin flaps in rats. Plast Reconstr Surg 2013;131:1024-34. https://doi.org/10.1097/PRS.0b013e3182879edf
  3. Gumus N, Odemis Y, Tuncer E, et al. The effect of topical minoxidil pretreatment on nonsurgical delay of rat cutaneous flaps: further studies. Aesthetic Plast Surg 2013;37:809-15. https://doi.org/10.1007/s00266-013-0161-x
  4. Thu VT, Kim HK, Long le T, et al. NecroX-5 prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter. Cardiovasc Res 2012;94:342-50. https://doi.org/10.1093/cvr/cvs122
  5. Park MK, Lee BD, Chae SW, et al. Protective effect of NecroX, a novel necroptosis inhibitor, on gentamicin-induced ototoxicity. Int J Pediatr Otorhinolaryngol 2012;76:1265-9. https://doi.org/10.1016/j.ijporl.2012.05.016

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