Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
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Intercontinental comparison of caustic ingestion in children

  • Rafeey, Mandana (Division of Gastroenterology, Tabriz Children's Hospital, Tabriz University Medical Sciences, Liver and Gastrointestinal Diseases Research Center) ;
  • Ghojazadeh, Morteza (Liver and Gastrointestinal Disease Research Center, Tabriz University of Medical Sciences) ;
  • Mehdizadeh, Amir (Liver and Gastrointestinal Disease Research Center, Tabriz University of Medical Sciences) ;
  • Hazrati, Hakimeh (Liver and Gastrointestinal Disease Research Center, Tabriz University of Medical Sciences) ;
  • Vahedi, Leila (Liver and Gastrointestinal Disease Research Center, Tabriz University of Medical Sciences)
  • Received : 2014.03.18
  • Accepted : 2014.08.29
  • Published : 2015.12.10
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Abstract

Purpose: To investigate the caustic ingestion in children among different continents according to demographic characteristics (core purpose), main symptoms, common caustic agents, signs and symptoms, management, treatment and complications. Methods: This systematic review was performed by searching the databases Science Direct, ProQuest, Google Scholar, and PubMed, electronically and manually. We included studies that were published from 1980 to 2013, at University of Medical Sciences of Tabriz, Iran. A strategic search was performed with keywords including caustic, corrosive, ingestion and children, and was limited to articles in English and Persian. Statistical analysis was performed by SPSS ver. 18. Results: Of 63 selected articles of caustic ingestion with 9,888 samples, the proportion of Africa was 3 articles (4.8%) and 95 samples (1%), America 9 articles (14.3%) and 305 sample (3%), Asia 29 articles (46%) and 2,780 samples (28.1%), Europe 17 articles (27%) and 3,002 samples (30.4%), and Oceania 5 articles (7.9%) and 3,706 samples (37.5%). The average age was in the Africa $3.07{\pm}2.02years$, America $3.17{\pm}1.83years$, Asia $3.34{\pm}1.58years$, Europe $3.58{\pm}2.09years$ and Oceania $3.52{\pm}2.02years$. Sex distribution was in Africa 76 males (0.91%) and 19 females (0.23%), America 49 males (0.58%) and 41 females (0.49%), Asia 1,575 males (18.76%) and 1,087 females (12.95%), Europe 1,018 males (12.13%) and 823 females (9.8%), and Oceania 1,918 males (22.85%) and 1,788 females (21.3%). Statistical analysis of the data indicated higher consumption in Europe and Oceania in the boys with higher average age of years. Conclusion: The comparison of caustic ingestion indicated that the cause substances of caustic ingestion in children are different among continents, therefore prevention strategy and different treatment guidelines among continents will be needed.

Keywords

References

  1. Pearn J, Nixon J, Ansford A, Corcoran A. Accidental poisoning in childhood: five year urban population study with 15 year analysis of fatality. Br Med J (Clin Res Ed) 1984;288:44-6. https://doi.org/10.1136/bmj.288.6410.44
  2. Reith DM, Pitt WR, Hockey R. Childhood poisoning in Queensland: an analysis of presentation and admission rates. J Paediatr Child Health 2001;37:446-50. https://doi.org/10.1046/j.1440-1754.2001.00666.x
  3. Broto J, Asensio M, Jorro CS, Marhuenda C, Vernet JM, Acosta D, et al. Conservative treatment of caustic esophageal injuries in children: 20 years of experience. Pediatr Surg Int 1999;15:323-5. https://doi.org/10.1007/s003830050591
  4. Ekpe EE, Ette V. Morbidity and mortality of caustic ingestion in rural children: experience in a new cardiothoracic surgery unit in Nigeria. ISRN Pediatr 2012;2012:210632.
  5. Bautista Casasnovas A, Estevez Martinez E, Varela Cives R, Villanueva Jeremias A, Tojo Sierra R, Cadranel S. A retrospective analysis of ingestion of caustic substances by children. Ten-year statistics in Galicia. Eur J Pediatr 1997;156:410-4. https://doi.org/10.1007/s004310050627
  6. Sawalha AF. Storage and utilization patterns of cleaning products in the home: toxicity implications. Accid Anal Prev 2007;39:1186-91. https://doi.org/10.1016/j.aap.2007.03.007
  7. Baskin D, Urganci N, Abbasoglu L, Alkim C, Yalcin M, Karadag C, et al. A standardised protocol for the acute management of corrosive ingestion in children. Pediatr Surg Int 2004;20:824-8. https://doi.org/10.1007/s00383-004-1294-4
  8. Atabek C, Surer I, Demirbag S, Caliskan B, Ozturk H, Cetinkursun S. Increasing tendency in caustic esophageal burns and long-term polytetrafluorethylene stenting in severe cases: 10 years experience. J Pediatr Surg 2007;42:636-40. https://doi.org/10.1016/j.jpedsurg.2006.12.012
  9. Lee HJ, Lee JH, Seo JM, Lee SK, Choe YH. A single center experience of self-bougienage on stricture recurrence after surgery for corrosive esophageal strictures in children. Yonsei Med J 2010;51: 202-5. https://doi.org/10.3349/ymj.2010.51.2.202
  10. Temiz A, Oguzkurt P, Ezer SS, Ince E, Hicsonmez A. Predictability of outcome of caustic ingestion by esophagogastroduodenoscopy in children. World J Gastroenterol 2012;18:1098-103. https://doi.org/10.3748/wjg.v18.i10.1098
  11. Mamede RC, de Mello Filho FV. Ingestion of caustic substances and its complications. Sao Paulo Med J 2001;119:10-5. https://doi.org/10.1590/S1516-31802001000100004
  12. Rigo GP, Camellini L, Azzolini F, Guazzetti S, Bedogni G, Merighi A, et al. What is the utility of selected clinical and endoscopic parameters in predicting the risk of death after caustic ingestion? Endoscopy 2002;34:304-10. https://doi.org/10.1055/s-2002-23633
  13. Thirlwall AS, Friedman N, Leighton SE, Saunders M, Jacob A, Kangesu L. Caustic soda ingestion: a case presentation and review of the literature. Int J Pediatr Otorhinolaryngol 2001;59:129-35. https://doi.org/10.1016/S0165-5876(01)00461-X
  14. Bicakci U, Tander B, Deveci G, Rizalar R, Ariturk E, Bernay F. Minimally invasive management of children with caustic ingestion: less pain for patients. Pediatr Surg Int 2010;26:251-5. https://doi.org/10.1007/s00383-009-2525-5
  15. Chen TY, Ko SF, Chuang JH, Kuo HW, Tiao MM. Predictors of esophageal stricture in children with unintentional ingestion of caustic agents. Chang Gung Med J 2003;26:233-9.
  16. Dogan Y, Erkan T, Cokugras FC, Kutlu T. Caustic gastroesophageal lesions in childhood: an analysis of 473 cases. Clin Pediatr (Phila) 2006;45:435-8. https://doi.org/10.1177/0009922806289618
  17. Arici MA, Ozdemir D, Oray NC, Buyukdeligoz M, Tuncok Y, Kalkan S. Evaluation of caustics and household detergents exposures in an emergency service. Hum Exp Toxicol 2012;31:533-8. https://doi.org/10.1177/0960327111412803
  18. Ferguson MK, Migliore M, Staszak VM, Little AG. Early evaluation and therapy for caustic esophageal injury. Am J Surg 1989;157: 116-20. https://doi.org/10.1016/0002-9610(89)90430-3
  19. Bychkova O, Lazyuk I, Averin V. Bio-degradable stents: a new approach to the treatment of caustic stenoses in children. Folia Gastroenterol Hepatol 2009;7:30-4.
  20. Gandhi RP, Cooper A, Barlow BA. Successful management of esophageal strictures without resection or replacement. J Pediatr Surg 1989;24:745-9. https://doi.org/10.1016/S0022-3468(89)80529-9
  21. Turner A, Robinson P. Respiratory and gastrointestinal complications of caustic ingestion in children. Emerg Med J 2005;22:359-61. https://doi.org/10.1136/emj.2004.015610

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