Textile Science and Engineering (한국섬유공학회지)

The Korean Fiber Society (한국섬유공학회)
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Effects of Phytoncide-containing Cotton Fabrics on the Development of Atopic Dermatitis

피톤치드를 함유하고 있는 의류소재가 아토피에 미치는 영향

  • Kim, Eui Hwa (Department of Textile Materials Engineering, Shinhan University)
  • 김의화 (신한대학교 섬유소재공학과)
  • Received : 2015.11.02
  • Accepted : 2015.12.04
  • Published : 2015.12.31
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Abstract

In this study, we investigated the effects of phytoncide-containing 100% cotton fabrics on the improvement of atopic dermatitis, through preclinical trials. The finishing agents used for testing were obtained by emulsification (S2), by capsulation (S4) using phytoncide extracted with supercritical $CO_2$, and by capsulation using solvent-extracted phytoncide (S3). The supercritically extracted phytoncide was used for in vitro testing. In the in vitro test, cytotoxicity occurred at the phytoncide concentrations of 0.1% and 0.5% in stained HaCaT cells and at 0.1% concentration in stained Raw 264.7 cells. In the in vivo test, the infiltration of inflammatory cells into skin tissue was significantly reduced in the S3 and S4 groups relative to the positive comparison group (Positive) of atopic dermatitis. Moreover, from results of the western blot and immunohistochemistry assays of tested skin tissue, we were able to confirm a reducing pattern of the markers related to keratogenesis.

Keywords

References

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