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보스턴 테리어에서 발생한 혀정맥 유래 목부위 곁신경절종 증례

Cervical Paraganglioma Originated from Lingual Vein in a Boston Terrier Dog

  • 장효미 (경상대학교 수의과대학 동물의학연구소) ;
  • 이희천 (경상대학교 수의과대학 동물의학연구소) ;
  • 최을수 (경상대학교 수의과대학 동물의학연구소) ;
  • 서정향 (건국대학교 수의병리학교실) ;
  • 정동인 (경상대학교 수의과대학 동물의학연구소)
  • Jang, Hyo-Mi (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • Lee, Hee-Chun (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • Choi, Eul-Soo (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • Sur, Jung-Hyang (Department of Pathobiology, Small Animal Tumor Diagnostic Center, College of Veterinary Medicine, Konkuk University) ;
  • Jung, Dong-In (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University)
  • 심사 : 2015.12.09
  • 발행 : 2015.12.31

초록

7살의 중성화된 수컷 보스턴테리어 개가 호흡곤란과 편측성 목부위 혹으로 내원하였다. 신체검사에서 왼쪽 아래턱밑 부위의 혹이 촉진되었다. 컴퓨터단층촬영 검사 결과 이 혹은 왼쪽 혀정맥 유래의 종양으로 의심되었다. 보호자의 거부로 치료가 진행되지 못했으며 내원 10일 후 호흡부전으로 폐사하였다. 부검에서 경계가 분명한 혹이 왼쪽 후두부위에서 확인되었으며 병리조직학적, 면역조직화학적 검사가 시행되었다. 컴퓨터단층촬영, 병리조직학적, 면역조직화학적 검사를 토대로 왼쪽 혀정맥에서 유래한 목부위 곁신경절종으로 최종진단되었다. 본 증례보고는 개에서 발생한 혀정맥 유래 목부위 곁신경절종의 임상적, 컴퓨터단층촬영, 병리조직학적 및 면역조직화학적 특징들을 잘 나타내고 있다.

A 7-year-old castrated male Boston terrier dog was referred due to dyspnea and unilateral cervical mass. On physical examination, mass on left submandibular region was palpated. CT findings revealed this case could be the tumor originated from left lingual vein. The client refused further treatment and the patient expired because of respiratory failure 10 days after presentation. On necropsy, a well-defined firm mass which located in the left side of larynx was detected. Histopathological findings for the mass indicated polygonal tumor cells arranged in nest and separated by fibrovascular septa. We performed immunohistochemisry to evaluate of chromogranin A and tumor cells showed positive immunoreactivity for chromogranin A. Based on computed tomography (CT), histopathological and immunohistochemical findings, this case was definitely diagnosed to paraganglioma of the body on the lingual vein. This report describes the clinical findings, CT imaging characteristics, histopathologic and immunohistochemical features of paraganglioma arised from lingual vein in a dog.

키워드

참고문헌

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피인용 문헌

  1. Primary Splenic Paraganglioma in a Dog vol.35, pp.4, 2018, https://doi.org/10.17555/jvc.2018.08.35.4.155