참고문헌
- Adachi K, Nikaido I, Ohta H, Ohtsuka S, Ura H, Kadota M, et al. Context-dependent wiring of Sox2 regulatory networks for self-renewal of embryonic and trophoblast stem cells. Mol Cell. 2013, 52(3): 380-392. https://doi.org/10.1016/j.molcel.2013.09.002
- Ann Pietrangelo, Brenda B. Spriggs. The outlook for ovarian cancer: prognosis, life expectancy & survival rates by stage. http://www.healthline.com/health/cancer/ovarian-cancer- outlook#Overview1, last visited on 2015, November 19.
- Becker KA, Ghule PN, Therrien JA, Lian JB, Stein JL, van Wijnen AJ, et al. Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase. Journal of cellular physiology. 2006, 209(3):883-893. https://doi.org/10.1002/jcp.20776
- Chien CS, Wang ML, Chu PY, Chang YL, Liu WH, Yu CC, et al. Lin28B/Let-7 regulates expression of Oct4 and Sox2 and reprograms oral squamous cell carcinoma cells to a stem-like state. Cancer Res. 2015, 75(21):2553-2565. https://doi.org/10.1158/0008-5472.CAN-14-2215
- Cimadamore F, Amador-Arjona A, Chen C, Huang CT, Terskikh AV. Sox2-Lin28/let-7 pathway regulates proliferation and neurogenesis in neural precursors. Proc Natl Acad Sci. 2013, 110(32):E3017-E30-26. https://doi.org/10.1073/pnas.1220176110
- Crawford M, Brawner E, Batte K, Yu L, Hunter MG, Otterson GA, et al. MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines. Biochem Biophys Res Commun. 2008, 373(4):607-612. https://doi.org/10.1016/j.bbrc.2008.06.090
- Eulalio A, Huntzinger E, Nishihara T, Rehwinkel J, Fauser M, Izaurralde E. Deadenylation is a widespread effect of miRNA regulation. RNA. 2009, 15(1):21-32.
- Hamano R, Miyata H, Yamasaki M, Sugimura K, Tanaka K, Kurokawa Y, et al. High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer. Br J Cancer. 2012, 106(8):1415-1423. https://doi.org/10.1038/bjc.2012.90
- Ittai BP, Matthew WT, Vincent JC, Ruping G, George WB, Aviv R, et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nature Genetics. 2008, 40:499-507. https://doi.org/10.1038/ng.127
- Li XM, Wang AM, Zhang J, Yi H. Down-regulation of micro-RNA-126 expression in colorectal cancer and its clinical significance. Med Oncol. 2011, 28(4):1054-1057. https://doi.org/10.1007/s12032-010-9637-6
- Li Y, Chen K, Li L, Li R, Zhang J, Ren W. Overexpression of Sox2 is involved in paclitaxel resistance of ovarian cancer via the PI3K/Akt pathway. Tumour Biol. 2015, 11:1-6.
- Lin F, Lin P, Zhao D, Chen Y, Xiao L, Qin W, et al. Sox2 targets cyclinE, p27 and survivin to regulate androgen-independent human prostate cancer cell proliferation and apoptosis. Cell Prolif. 2012, 45(3):207-216. https://doi.org/10.1111/j.1365-2184.2012.00812.x
- Liu B, Peng XC, Zheng XL, Wang J, Qin YW. MicroRNA-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo. Lung Cancer. 2009, 66(2):169-175. https://doi.org/10.1016/j.lungcan.2009.01.010
- Liu LY, Wang W, Zhao LY, Guo B, Yang J, Zhao XG, et al. MicroRNA-126 inhibits growth of SGC-7901 cells by synergistically targeting the oncogenes PI3KR2 and Crk, and the tumor suppressor PLK2. Int J Oncol. 2014, 45(3):1257-1265. https://doi.org/10.3892/ijo.2014.2516
- Luo P, Fei J, Zhou J, Zhang W. microRNA-126 suppresses PAK4 expression in ovarian cancer SKOV3 cells. Oncol Lett. 2015, 9(5):2225-2229. https://doi.org/10.3892/ol.2015.3012
- Ma W, Ma J, Xu J, Qiao C, Branscum A, Cardenas A, et al. Lin28 regulates BMP4 and functions with Oct4 to affect ovarian tumor microenvironment. Cell Cycle. 2013, 12(1):88-97. https://doi.org/10.4161/cc.23028
- McLean K, Gong Y, Choi Y, Deng N, Yang K, Bai S, et al. Human ovarian carcinoma-associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production. J Clin Invest. 2011, 121(8):3206-3219. https://doi.org/10.1172/JCI45273
- Nguyen LV, Vanner R, Dirks P, Eaves CJ. Cancer stem cells: an evolving concept. Nat Rev Cancer. 2012, 12:133-143. https://doi.org/10.1038/nrc3184
- Otsubo T, Akiyama Y, Hashimoto Y, Shimada S, Goto K, Yuasa Y. MicroRNA-126 inhibits Sox2 expression and contributes to gastric carcinogenesis. PLoS One. 2011, 6(1):e16617. https://doi.org/10.1371/journal.pone.0016617
- Peng S, Maihle NJ, Huang Y. Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer. Oncogene. 2010, 29(14):2153-2159. https://doi.org/10.1038/onc.2009.500
- Park CE, Hong SN. Expression patterns of cell cycle related genes mRNA and proteins in the mouse ovary. Korean J Clin Lab Sci. 2006, 38:72-81.
- Park CE, Kim DJ, Hong SN. Expression of mRNAs and proteins of cyclin A and LATS genes in ovary. Korean J Clin Lab Sci. 2008, 40:31-40.
- Saito Y, Friedman JM, Chihara Y, Egger G, Chuang JC, Liang G. Epigenetic therapy upregulates the tumor suppressor micro-RNA-126 and its host gene EGFL7 in human cancer cells. Biochem Biophys Res Commun. 2009, 379(3):726-731. https://doi.org/10.1016/j.bbrc.2008.12.098
- Sales KM, Winslet MC, Seifalian AM. Stem cells and cancer: an overview. Stem Cell Rev. 2007, 3(4): 249-255. https://doi.org/10.1007/s12015-007-9002-0
- Schoenhals M, Kassambara A, De Vos J, Hose D, Moreaux J, Klein B. Embryonic stem cell markers expression in cancers. Biochem Biophys Res Commun. 2009, 383(2):157-162. https://doi.org/10.1016/j.bbrc.2009.02.156
- Shen WF, Hu YL, Uttarwar L, Passegue E, Largman C. Micro-RNA-126 regulates HOXA9 by binding to the homeobox. Mol Cell Biol. 2008, 28(14):4609-4619. https://doi.org/10.1128/MCB.01652-07
- Sun Y, Bai Y, Zhang F, Wang Y, Guo Y, Guo L. microRNA-126 inhibits non-small cell lung cancer cells proliferation by targeting EGFL7. Biochem Biophys Res Commun. 2010, 391(3):1483-1489. https://doi.org/10.1016/j.bbrc.2009.12.098
- Viswanathan SR, Powers JT, Einhorn W, Hoshida Y, Ng TL, Toffanin S, et al. Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet 2009, 41: 843-848. https://doi.org/10.1038/ng.392
- Williams AE. Functional aspects of animal microRNAs. Cell. Mol. Life Sci. 2008, 65(4):545-562. https://doi.org/10.1007/s00018-007-7355-9
- Xu B, Zhang K, Huang Y. Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells. RNA. 2009, 15:357-361. https://doi.org/10.1261/rna.1368009
- Zhang J, Du YY, Lin YF, Chen YT, Yang L, Wang HJ, et al. The cell growth suppressor, microRNA-126, targets IRS-1. Biochem Biophys Res Commun. 2008, 377(1):136-140. https://doi.org/10.1016/j.bbrc.2008.09.089
- Zhang Q, Zeng S, Quan C, Lin X. Induction function of microRNA-126 in survival and proliferation in neural stem cells. Med Sci Monit. 2015, 21:3023-3027. https://doi.org/10.12659/MSM.894672