Culinary science and hospitality research (한국조리학회지)

Culinary Society of Korean Academy (한국조리학회)
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Effects of Small Colored Potato Extracts by High-Pressure Extraction on Serum Lipid Levels in High Fat Diet Fed Rats

꼬마색깔감자 초고압 추출물이 고지방식이를 섭취한 흰쥐의 혈청지질농도개선 미치는 영향

  • Rha, Young-Ah (Dept. of Food Science and Services, Eulji University) ;
  • Choi, Mi-Sook (Dept. of Food Science and Services, Eulji University) ;
  • Kwon, Min-Soo (Rokya Agricultural Corp.) ;
  • Hwang, Young-Jeong (Dept. of Food Science & Culinary Arts, International University of Korea) ;
  • Park, Sung-Jin (Dept. of Tourism Food Service Cuisine, Hallym Polytechnic University, Research Institute of Biomaterial, Hallym Polytechnic University)
  • 나영아 (을지대학교 식품산업외식학과) ;
  • 최미숙 (을지대학교 식품산업외식학과) ;
  • 권민수 (농업회사법인 록야 주식회사) ;
  • 황영정 (한국국제대학교 외식조리학과) ;
  • 박성진 (한림성심대학교 관광외식조리과/한림성심대학교 생물소재연구소)
  • Received : 2014.06.10
  • Accepted : 2014.08.10
  • Published : 2014.08.31
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Abstract

We investigated the anti-obesity effects of small colored potato extracts by high pressure water extraction process on body weight, plasma lipid levels in high-fat diet-induced obese mice. Experimental groups were divided into basal diet only (Normal), high fat diet control (HFD), small colored potato water extracts (CP), and high-fat diet and small colored potato water high pressure extracts (HCP) groups. The levels of hematological variables were not significantly different among the four groups. Compared with the HFD group's serum total cholesterol level of $86.01{\pm}1.16mg/dL$, the levels of the CP and HCP groups were significantly lowered to $80.29{\pm}1.28$ and $77.21{\pm}4.21mg/dL$, respectively. Compared with the HFD group's LDL-cholesterol level of $18.92{\pm}2.44mg/dL$, the LDL-cholesterol levels of the CP and HCP groups were significantly lowered to $13.52{\pm}1.26$ and $12.93{\pm}1.26mg/dL$, respectively. Also, compared to the HFD group's serum triglyceride level of $82.71{\pm}3.94mg/dL$, the level of the HCP group was significantly lowered to $63.24{\pm}6.32mg/dL$. These results suggested that dietary supplementation of small colored potato extracts using high pressure water extraction does not have any adverse effects on the hematological variables, while improving the lipid content and reducing hepatic damage of the high-fat fed rats.

고지방식이로 비만 및 고지혈이 유발된 실험동물에서 체중, 혈중지질, 혈청생화학적 검사 및 장기무게를 측정하여 추출공정에 따른 꼬마색깔감자 추출물 투여로 인한 혈중지질 개선 및 꼬마색깔감자 추출물의 간기능 및 장기무게 변화에 미치는 영향에 대해 조사하였다. 체중 및 사료이용 효율은 고지방식이에 의해 대조군에서 증가현상을 보였으며, 꼬마색깔감자 추출물 투여군 시험군(CP군, HCP군)에서 꼬마색깔감자 추출물 투여로 인한 체중증가량 감소와 식이효율 감소현상을 보였다. 혈청 생화학적 검사에서 고지방식이에 의해 혈중 ALT, AST, 총단백의 변화가 관찰되었으며, 꼬마색깔감자 추출물 투여에 의해 정상군 군과 비슷한 수준으로 유지되는 것을 볼 수 있었다. 혈중 creatinine과 g-GT의 경우 고지방식이 및 꼬마색깔감자 추출물 투여에 의한 변화는 관찰되지 않았다. 혈중지질 변화는 총 콜레스테롤, LDL-콜레스테롤, triglyceride, 동맥경화지수(AI) 모두 고지방식이에 의해 유의적인 증가현상을 보였으며, 꼬마색깔감자 추출물 투여로 인한 혈중지질 변화를 관찰할 수 있었다. 이상의 실험결과, 추출 공정 중 초고압 공정을 통한 꼬마색깔감자 추출물은 비만유도 흰쥐에서 체중, 간, 지방조직의 무게 감소와 더불어 혈청의 지질성상의 개선에 더욱 효과적으로 영향을 미치는 것으로 나타났다. 이러한 결과는 초고압 공정을 통한 꼬마색깔감자 추출물에 함유된 다량의 안토시아닌 및 폴리페놀 등의 생리활성 물질이 지질대사를 개선시키고 지방 축적을 억제하는 것으로 판단된다. 꼬마색깔감자 추출물은 비만, 고지혈증, 이상지혈증의 예방 및 개선 효과를 나타낼 것으로 기대하는 바이며 나아가 심혈관계 질환의 예방 및 치료에 긍정적인 효과가 있을 것으로 사료된다.

Keywords

References

  1. Bennett PB, Marquis RE, Demchenko I (1998) High pressure biology and medicine. University of Rochester Press, New York, USA. p. 1-428
  2. Cha JY, Cho YS, Kim DJ (2001) Effect of chicory extract on the lipid metabolism and oxidative stress in rats. J Korean Soc Food Sci Nutr 30(6): 1220-1226
  3. Cha WS, Kim CK, Kim JS (2002) On the Development of functional health beverages using Citrus reticulate, Ostrea gigas. Korean J Biotechnol Bioeng 17(5): 503-507
  4. Chapman MJ (2006) Therapeutic elevation of HDL-cholesterol to prevent atherosclerosis and coronary heart disease. Pharmacol Ther 111(3): 893-908 https://doi.org/10.1016/j.pharmthera.2006.02.003
  5. Choi HD, Lee HC, Kim SS, Kim YS, Lom HT, Ryu GH (2008) Nutrient components and hysicochemical properties of new domestic potato cultivars. Kor J Food Sci Technol 40(4):382-388
  6. Choi MS, Do DH, Choi DJ (2002) The effect of mixing beverage with Aralia continentalis Kitagawa root on blood pressure and blood constituents of the diabetic and hypertensive elderly. Korean J Food & Nutr 15(2): 165-172
  7. Despres JP, Lemicux I, Dagenais GR, Cantin B, Lamarche B (2000) HDL-cholesterol as a marker of coronary heart disease risk: The Quebec cardiovascular study. Atherosclerosis 153(2): 263-272 https://doi.org/10.1016/S0021-9150(00)00603-1
  8. Han JH, Song YJ, Park SH (2004) Development of drink from composition with medicinal plants and evaluation of its physiological function in Aorta relaxation. Korean J Oriental Physiology & Pathology 18(4): 1078-1082
  9. Horie Y, Kimura K, Ida M, Yosida Y, Ohki K (1991) Jam preparation by pressurization. Nippon Nogeikagaku Kaishi 65(6): 975-980 https://doi.org/10.1271/nogeikagaku1924.65.975
  10. Jang HL, Hong JY, Kim NJ, Kim NH, Shin SR, Yoon KY (2011) Comparision of nutritent components and physicochemical properties of general and colored potato. Kor J Hort Sci Technol 29(2): 144-150
  11. Hur J (2007) Effect of citrate and phosphate on the inhibition of browing in minimally processed potatoes. Korean J Culinary Res 13(2):254-259.
  12. Kang HK, No JK, Sung DY, Kim ND, Lee KH, Kim KW, Choi WC, Yim UK, Yoo BP, Jung HY (1997) Effects of aging and dietary restriction on free radical generation and GSH/GSSG level in rat testis. Kor J Gerontol 7(3): 92-97
  13. Kim JH, Park JH, Park SD, Choi SY, Seong JH, Moon KD (2002) Preparation and antioxidant activity of health drink with extract powders from safflower(Carthamus tinctorius L.) seed. Korean J Food Sci Technol 34(4): 617-624
  14. Kim JI, Cho SJ, Lee YI, Bae DS, Lee SJ, Kim JS (1984) The serum NPN, BUN and creatinine values in the patient with congestive heart failure. Korean J Inter Med 27(2):145-149
  15. Kolasa KM (1993). The potato and human nutrition. Amer J Potato Res 70(5): 375-384 https://doi.org/10.1007/BF02849118
  16. Kwag JS, Baek SH (2003) Cytotoxicity and antimicrobial effects of extracts from Salvia miltorrhiza. Korean J Pharmacogn 34(4): 293-296
  17. Law MR, Wald NJ (1994) An ecological study of serum cholesterol and ischaemic heart disease between 1950 and 1990. Eur J Clin Nutr 48(5):305-325
  18. Lee JS, Hwang YJ (2003) A study of rheology with cooking methods of potato. Korean J Culinary Res 9(2): 85-97
  19. Lee SH, Lee YS (1998) Effects of late-harvested green tea extracted on lipid metabolism and Ca absorption in rats. Korean J Nutr 31(6):999-1005
  20. Oh YS (2007). Quality characteristics of snow crab cream soup with yam and potato as a thickening agents. Korean J Culinary Res 13(1): 112-118
  21. Park CH, Jung HK, Jeong YS, Hong JH, Lee GD, Park CH (2011) Effects of citrus peel ethanol extract on the serum lipid and body fat of high-fat-diet-fed rats. Korean J Food Preserv 18(4): 567-574 https://doi.org/10.11002/kjfp.2011.18.4.567
  22. Park JH, Lee HS, Mun HC, Kim DH, Seong NS, Jung HG, Bang JK, Lee HY (2004) Effect of ultrasonification process on enhancement of immuno-stimulatory activity of Ephedra sinica Stapf and Rubus coreanus Miq. Korean J Biotechnol Bioeng 19(2):113-117
  23. Park KS (2006) Metabolic Syndrome. Korean Diabetes Association 7(1): 37-44.
  24. Park SH, Han JH (2003) The effects of uncooked powdered food on nutrient intake, serum lipid level, dietary behavior and health index in healthy women. J Nutri 36(1): 49-63
  25. Poulter N (1999) Coronary heart disease is a multifactorial disease. Am J Hypertens 12(S6):92S-95S
  26. Schaefer EJ, Lichtenstein AH, Lamon-Fava S, Mcnamara JR, Ordovas JM (1995) Lipoprotein, nutrition, aging and atherosclerosis. Am J Clin Nutr 61(3): 726-730 https://doi.org/10.1093/ajcn/61.3.726S
  27. Sendecor GW, Cochrane WG (1967) Statistical methods. 6th ed., Iowa State University Press, Iowa, p.1.