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Acute Upper Limb Ischemia Suspected to Have Originated from Staphylococcus Epidermidis Native Valve Endocarditis

자연판막 심내막염에 동반된 급성 상지 허혈을 치료한 1예

  • Jang, Seong Pil (Department of Internal Medicine, Busan Medical Center) ;
  • Choi, Jae Hoon (Department of Internal Medicine, Busan Medical Center) ;
  • Yang, Mi Jin (Department of Internal Medicine, Busan Medical Center) ;
  • Kim, Hong Je (Department of Internal Medicine, Busan Medical Center) ;
  • Hwang, Cheol Gu (Department of Internal Medicine, Busan Medical Center) ;
  • Kim, Ji Ha (Department of Internal Medicine, Busan Medical Center) ;
  • Han, Dong Hun (Department of Internal Medicine, Busan Medical Center)
  • 장성필 (부산광역시의료원 내과) ;
  • 최재훈 (부산광역시의료원 내과) ;
  • 양미진 (부산광역시의료원 내과) ;
  • 김홍제 (부산광역시의료원 내과) ;
  • 황철구 (부산광역시의료원 내과) ;
  • 김지하 (부산광역시의료원 내과) ;
  • 한동훈 (부산광역시의료원 내과)
  • Received : 2013.06.05
  • Accepted : 2013.08.26
  • Published : 2014.07.01

Abstract

We report a case of acute upper limb ischemia suspected to have originated from methicillin-resistant Staphylococcus epidermidis native valve endocarditis in a 57-year-old man who had complained of sudden-onset fever and pain in the right hand. 3D computed tomography of the right upper extremity detected a thrombus occluding the brachial artery. Echocardiography showed a large vegetation on the aortic valve. Thus, we suspected, clinically, brachial artery occlusion by septic emboli originating from a large vegetation of the aortic valve. The patient was treated with intravenous antibiotics for the suspected methicillin-resistant Staphylococcus epidermidis-native valve endocarditis with a combination of percutaneous aspiration thromboembolectomy and selective intra-arterial thrombolysis for acute thromboembolic occlusion in the right upper limb. The large vegetation of the aortic valve resolved without surgery and aortic regurgitation improved. The patient recovered uneventfully with no complications, including septic embolism, over the following 11 months.

급성 상지 허혈과 감염성 심내막염은 각각 자연경과가 치명적으로 나타날 수 있기 때문에 초기에 빠르게 진단을 내리고 치료하는 것이 환자의 예후를 개선할 수 있지만 쉽지 않다. 전신 색전증은 감염성 심내막염 환자의 진단기준에 포함되어 있을 만큼 비교적 흔한 증상이지만 자연판막 심내막염에서 메티실린 내성 표피포도상구균이 배양되는 경우에서 발생한 증례는 드물다. 저자들은 자연판막 심내막염에 따른 전신 색전증으로 인해 발생한 급성 상지 허혈 환자에서 흡인 혈전색전제거술와 선택적 동맥 내 혈전용해술의 중재적 시술을 통해 성공적으로 혈관 재개통과 사지구제를 하였다. 대동맥 판막을 침범한 크고 잘 움직이는 증식물에 대해서도 수술 없이 적절한 항균제 치료만으로 경식도 초음파에서 증식물의 크기 감소와 소멸을 확인하였으며 이후 11개월 동안 별다른 합병증 없이 추적관찰 중이다.

Keywords

References

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