The Korean Journal of Medicine

  • 제86권3호
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  • Pages.357-361
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  • 2014
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  • 1738-9364(pISSN)
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  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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Sclerosing Angiomatoid Nodular Transformation of Spleen 1예: 스포크 휠(Spoke Wheel) 모양의 조영증강

A Case of Sclerosing Angiomatoid Nodular Transformation of the Spleen: Spoke Wheel Pattern on Computed Tomography

  • 박주한 (아주대학교 의과대학 아주대학교병원 혈액종양내과) ;
  • 황선혁 (아주대학교 의과대학 아주대학교병원 혈액종양내과) ;
  • 김기찬 (아주대학교 의과대학 아주대학교병원 혈액종양내과) ;
  • 김시연 (아주대학교 의과대학 아주대학교병원 혈액종양내과) ;
  • 송가원 (아주대학교 의과대학 아주대학교병원 혈액종양내과) ;
  • 한재호 (아주대학교 의과대학 아주대학교병원 병리과) ;
  • 박준성 (아주대학교 의과대학 아주대학교병원 혈액종양내과)
  • Park, Joo Han (Department of Hematology-Oncology, Ajou University School of Medicine) ;
  • Hwang, Sun Hyuk (Department of Hematology-Oncology, Ajou University School of Medicine) ;
  • Kim, Ki Chan (Department of Hematology-Oncology, Ajou University School of Medicine) ;
  • Kim, Si Yeon (Department of Hematology-Oncology, Ajou University School of Medicine) ;
  • Song, Ga Won (Department of Hematology-Oncology, Ajou University School of Medicine) ;
  • Han, Jae Ho (Department of Pathology, Ajou University School of Medicine) ;
  • Park, Joon Seong (Department of Hematology-Oncology, Ajou University School of Medicine)
  • 투고 : 2013.06.20
  • 심사 : 2013.10.01
  • 발행 : 2014.03.01
⟨ 이전 논문 다음 논문 ⟩

초록

SANT는 비장에 발생하는 매우 드문 양성 종양으로 대부분은 증상이 없어 우연히 발견되는 경우가 대부분이며 영상학적으로 확진이 어렵기 때문에 수술적 절제술을 시행하고 병리조직검사를 통해 진단을 내리게 된다. SANT는 현재까지 세계적으로 보고된 증례가 많지 않으며 그 특징이 명확히 보고된 바 없어 SANT 증례에 대해 보고하고 그 감별점에 대해 고찰하는 바이다.

Sclerosing angiomatoid nodular transformation (SANT) is a rare, benign vascular neoplasm. Most patients have no clinical symptoms, and the tumors are usually discovered incidentally on abdominal computed tomography or ultrasonography. Some studies have reported the clinical features and imaging findings of SANT, but the diagnosis is based on histopathologic examination of a tissue specimen obtained at splenectomy. We report herein an incidentally discovered case of SANT and review the related literature.

키워드

참고문헌

  1. Martel M, Cheuk W, Lombardi L, Lifschitz-Mercer B, Chan JK, Rosai J. Sclerosing angiomatoid nodular transformation (SANT): report of 25 cases of a distinctive benign splenic lesion. Am J Surg Pathol 2004;28:1268-1279. https://doi.org/10.1097/01.pas.0000138004.54274.d3
  2. Kim KH, Lee S, Youn SH, et al. Laparoscopic splenectomy for sclerosing angiomatoid nodular transformation of the spleen. J Korean Surg Soc 2011;80(Suppl 1):S59-62. https://doi.org/10.4174/jkss.2011.80.Suppl1.S59
  3. Giovagnoni A, Giorgi C, Goteri G. Tumours of the spleen. Cancer Imaging 2005;5:73-77. https://doi.org/10.1102/1470-7330.2005.0002
  4. Awamleh AA, Perez-Ordonez B. Sclerosing angiomatoid nodular transformation of the spleen. Arch Pathol Lab Med 2007;131:974-978.
  5. Lee HJ, Choi SY, Huang SM, Sul JY, Kim JM. Sclerosing angiomatoid nodular transformation (SANT) in spleen: a case report. Korean J Pathol 2011;45:111-114. https://doi.org/10.4132/KoreanJPathol.2011.45.1.111
  6. Thacker C, Korn R, Millstine J, Harvin H, Van Lier Ribbink JA, Gotway MB. Sclerosing angiomatoid nodular transformation of the spleen: CT, MR, PET, and $^{99}$(m)Tc-sulfur colloid SPECT CT findings with gross and histopathological correlation. Abdom Imaging 2010;35:683-689. https://doi.org/10.1007/s00261-009-9584-x
  7. Li L, Fisher DA, Stanek AE. Sclerosing angiomatoid nodular transformation (SANT) of the spleen: addition of a case with focal CD68 staining and distinctive CT features. Am J Surg Pathol 2005;29:839-841.
  8. Cao JY, Zhang H, Wang WP. Ultrasonography of sclerosing angiomatoid nodular transformation in the spleen. World J Gastroenterol 2010;16:3727-3730. https://doi.org/10.3748/wjg.v16.i29.3727
  9. Kuo TT, Chen TC, Lee LY. Sclerosing angiomatoid nodular transformation of the spleen (SANT): clinicopathological study of 10 cases with or without abdominal disseminated calcifying fibrous tumors, and the presence of a significant number of IgG4+ plasma cells. Pathol Int 2009;59:844-850. https://doi.org/10.1111/j.1440-1827.2009.02456.x
  10. Kaza RK, Azar S, Al-Hawary MM, Francis IR. Primary and secondary neoplasms of the spleen. Cancer Imaging 2010;10:173-182. https://doi.org/10.1102/1470-7330.2010.0026

피인용 문헌

  1. Sclerosingangiomatoid nodular transformation of spleen in a pediatric malignancy patient vol.63, pp.6, 2014, https://doi.org/10.1111/ped.14491