The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Dermatomyositis in an Allogeneic Stem Cell Transplant Recipient with Graft-Versus-Host Disease

조혈모세포 이식 후 발생한 만성 이식편대숙주반응 연관 피부근염 1예

  • Kim, Young (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Kang, Seong Wook (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Jo, Deog-Yeon (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Park, Chan-Keol (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Song, Kyu Sang (Department of Pathology, Chungnam National University School of Medicine) ;
  • Kim, Jin-Man (Department of Pathology, Chungnam National University School of Medicine) ;
  • Kim, Jinhyun (Department of Internal Medicine, Chungnam National University School of Medicine)
  • 김영 (충남대학교 의학전문대학원 내과학교실) ;
  • 강성욱 (충남대학교 의학전문대학원 내과학교실) ;
  • 조덕연 (충남대학교 의학전문대학원 내과학교실) ;
  • 박찬걸 (충남대학교 의학전문대학원 내과학교실) ;
  • 송규상 (충남대학교 의학전문대학원 병리학교실) ;
  • 김진만 (충남대학교 의학전문대학원 병리학교실) ;
  • 김진현 (충남대학교 의학전문대학원 내과학교실)
  • Received : 2013.07.10
  • Accepted : 2013.09.12
  • Published : 2014.04.01
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Abstract

Dermatomyositis (DM) is an autoimmune disease characterized by subacute-onset proximal symmetric muscle weakness, skin abnormalities, and muscle inflammation. Descriptions of DM as a complication of chronic graft-versus-host disease (cGVHD) are very rare. We report a 50-year-old woman who developed DM associated with cGVHD after allogeneic stem cell transplantation.

피부근염은 특징적인 근생검 결과와 함께 피부증상과 근위부 근력의 대칭적 약화 및 특징적 근전도 소견 및 CK의 상승 등을 특징으로 하는 질환이다. 드물게 조혈모세포 이식후에 발병하는 경우도 보고되었다. 저자들은 동종 조혈모세포 이식 후 만성 이식편대숙주병이 있는 환자에서 발생한 피부근염의 증례를 경험하여 보고하는 바이다.

Keywords

References

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