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주의력결핍 과잉운동장애 소아에서 배뇨장애와 변비의 유병률

Prevalence of Voiding Dysfunction and Constipation in Children with Attention Deficit Hyperactivity Disorder

  • 김준영 (한림대학교 의과대학 소아과학교실) ;
  • 이은섭 (한림대학교 의과대학 소아과학교실) ;
  • 방지석 (한림대학교 의과대학 소아과학교실) ;
  • 오연정 (한림대학교 의과대학 소아과학교실) ;
  • 이용주 (한림대학교 의과대학 소아과학교실) ;
  • 성태정 (한림대학교 의과대학 소아과학교실) ;
  • 이건희 (한림대학교 의과대학 소아과학교실) ;
  • 이정원 (한림대학교 의과대학 소아과학교실)
  • Kim, Joon Young (Department of Pediatrics, Hallym University Medical Center, Kangnam Sacred Heart Hospital) ;
  • Lee, Eun Seob (Department of Pediatrics, Hallym University Medical Center, Kangnam Sacred Heart Hospital) ;
  • Bang, Ji Seok (Department of Pediatrics, Hallym University Medical Center, Kangnam Sacred Heart Hospital) ;
  • Oh, Yeon Joung (Department of Pediatrics, Hallym University Medical Center, Kangnam Sacred Heart Hospital) ;
  • Lee, Yong Ju (Department of Pediatrics, Hallym University Medical Center, Kangnam Sacred Heart Hospital) ;
  • Sung, Tae-Jung (Department of Pediatrics, Hallym University Medical Center, Kangnam Sacred Heart Hospital) ;
  • Lee, Kon-Hee (Department of Pediatrics, Hallym University Medical Center, Kangnam Sacred Heart Hospital) ;
  • Lee, Jung Won (Department of Pediatrics, Hallym University Medical Center, Kangnam Sacred Heart Hospital)
  • 투고 : 2014.07.11
  • 심사 : 2014.08.27
  • 발행 : 2014.10.31

초록

목적: 주의력결핍 과잉운동장애(ADHD)는 소아에서 3-5%의 유병률을 보이며 전두엽의 억제기전 저하와 대뇌의 카테콜라민 대사이상이 관련된다고 알려져 있다. ADHD 환아에서 야뇨증을 비롯한 다양한 하부요로계 증상을 동반한다는 보고가 있지만 국내에서는 ADHD 환아들에 대한 보고가 없기에 저자들은 ADHD 환아에서 배뇨증상을 알아보기 위해 본 연구를 시행하였다. 방법: 2009년 10월부터 2011년 3월까지 DSM-IV 진단기준에 근거하여 ADHD로 진단받은 33명의 환아들과 같은 기간 동안 신경계 질환이나 요로계 질환 없이 상기도 감염으로 외래를 내원한 환아 30명을 대상으로 배뇨와 배변에 대한 설문지를 시행하였다. 결과: ADHD 환자군의 평균 연령은 $9.09{\pm}2.8$세(남 28: 여 5) 이었고, 대조군의 평균 연령은 $8.58{\pm}3.1$ (남 20: 여 10) 이었다. ADHD 환아군에서 대조군에 비해 요절박(P=0.017), 절박 요실금(P=0.033), 변비(P=0.045)의 유병률이 대조군에 비해 유의하게 높았고, 복압배뇨, 간헐뇨, 배뇨지연 행동에는 두 군간에 유의한 차이가 없었다. 야뇨증은 ADHD 환아군에서 12.1% (4/33)로 대조군의 0%에 비해 많았지만 통계학적인 유의성은 없었다. 결론: ADHD 환아는 대조군에 비해 요절박, 절박 요실금과 변비의 유병률이 유의하게 높았다.

Purpose: Attention deficit hyperactivity disorder (ADHD) has been associated with impairments in frontal inhibitory function and the catecholaminergic system. ADHD is diagnosed in 3-5% of children. Children with ADHD seem develop various forms of urinary problems such as nocturnal enuresis, dysfunctional voiding, and diurnal incontinence. However, no data exist to confirm the presence of these problems in Korean children with ADHD. We investigated the clinical findings of voiding dysfunction in children with ADHD. Methods: Between October 2009 and March 2011, a total of 63 children (33 with ADHD, 30 with an upper respiratory infection, as a control group) were enrolled. ADHD was diagnosed using the diagnostic and statistical manual of mental disorders (DSM)-IV criteria. A comprehensive survey of voiding and defecation was administered. Results: The patient group included 28 boys and 5 girls; the control group comprised 20 boys and 10 girls. The mean age was $9.09{\pm}2.8$ years in the ADHD group and $8.58{\pm}3.1$ years in the control group. Children with ADHD had a statistically significantly higher incidence of urgency (P =0.017), urge incontinence (P =0.033), and constipation (P =0.045). There was no significant difference in the incidence of straining, intermittency, holding maneuvers, or nocturnal enuresis. Conclusion: Children with ADHD in Korea have significantly higher rates of urgency, urge incontinence, and constipation than those without ADHD.

키워드

참고문헌

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