Journal of Digital Convergence (디지털융복합연구)

The Society of Digital Policy and Management (한국디지털정책학회)
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Distribution of Yeast Isolated from Clinical Specimens at a University Hospital in last Five Years

최근 5년간 단일 대학병원의 임상검체에서 분리된 효모균의 분포

  • Seo, Choong-Won (Dept. of Biomedical Laboratory Science, Seonam University) ;
  • Yu, Young-Bin (Dept. of Biomedical Laboratory Science, Konyang University) ;
  • Shin, Kyeong Seob (Dept. of Laboratory Medicine, Chungbuk National University College of Medicine) ;
  • Kim, Young-Kwon (Dept. of Biomedical Laboratory Science, Konyang University)
  • 서충원 (서남대학교 임상병리학과) ;
  • 유영빈 (건양대학교 임상병리학과) ;
  • 신경섭 (충북의과대학 진단검사의학과) ;
  • 김영권 (건양대학교 임상병리학과)
  • Received : 2014.06.18
  • Accepted : 2014.09.20
  • Published : 2014.09.28
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Abstract

Pathogenic fungal infections are predominantly occurred in patients with severe immune or metabolic defects. In the present study, we aimed to investigate the last five years (2007~2011) 190,250 cases clinical specimens of yeast 3,487 results that had shown positive culture and to look at the significance of regional difference and identify relationship between provide the characteristics about association between clinical isolates and gender, age, and type of specimens. The yearly strain-specific isolation frequency of yeast separated was 1,925(55.2%) for C. albicans the largest of them. All kinds of clinical specimen was 1,495(42.9%) in urine, 998(28.6%) in sputum. Strain-specific gender differences in C. albicans for males was 1,177(57.8%) of the total of 2,037 and 748(51.6%) of 1,450 and as for age, those between 70 and 79 were the largest with 639(55.1%) of the 1,925 strain. In this study, well presented the general characteristics of pathogenic yeast seen in diverse specimens. This limitation has been implemented in a single area, Future research is expected to examine more on nationwide distribution chart, dynamic characteristics and future antibiotic sensitivity.

병원성 진균감염은 환자가 심각한 면역 또는 신진 대사 결함이 있거나 수술을 받았을 때 발생한다. 본 연구에서는 5년(2007-2011)간 임상에서 의뢰된 검체 190,250건을 대상으로 배양에서 양성으로 판정된 효모균 3,487주(1.83%)의 분리빈도를 조사하여 지역적인 차이의 유의성을 보고 진균의 종류와 연도, 검체 및 일반적인 특징인 연령과 성별에 따른 분리빈도의 연관성을 파악하였다. 효모균의 균주별 연 분리빈도는 C. albicans 1,925주(55.2%)로 가장 많이 분리되었다. 임상 검체는 소변 1,495건(42.9%), 객담 998건(28.6%)으로 나타났고, 성별의 차이는 C. albicans가 남자는 2,037명 중 1,177명(57.8%), 여자는 1,450명 중 748명(51.6%)이었고, 연령은 1,925주 중 70-79세가 639명(55.1%)으로 많이 분리되었다. 이 연구에서는 다양한 검체에서 나타나는 병원성을 가진 효모균의 일반적인 특성을 잘 나타내었다. 단일지역에서 시행한 제한점이 있고, 전국적인 분포도나 역학적인 특성과 추후 항생제 감수성을 분석한다면 더 좋은 연구가 될 것이라고 사료된다.

Keywords

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