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Curcumin, COX-2, and Protein p300/CBP

  • Jung, Ki Tae (Department of Anesthesiology and Pain Medicine, Chosun University School of Medicine) ;
  • Lim, Kyung Joon (Department of Anesthesiology and Pain Medicine, Chosun University School of Medicine)
  • Received : 2014.09.11
  • Accepted : 2014.09.14
  • Published : 2014.10.01

Abstract

Keywords

References

  1. Kapoor S. Curcumin and its emerging role in pain modulation and pain management. Korean J Pain 2012; 25: 202-3. https://doi.org/10.3344/kjp.2012.25.3.202
  2. Moini Zanjani T, Ameli H, Labibi F, Sedaghat K, Sabetkasaei M. The attenuation of pain behavior and serum COX-2 concentration by curcumin in a rat model of neuropathic pain. Korean J Pain 2014; 27: 246-52. https://doi.org/10.3344/kjp.2014.27.3.246
  3. Aggarwal BB, Harikumar KB. Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. Int J Biochem Cell Biol 2009; 41: 40-59. https://doi.org/10.1016/j.biocel.2008.06.010
  4. Mukherjee SP, Behar M, Birnbaum HA, Hoffmann A, Wright PE, Ghosh G. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-${\kappa}$B-driven transcription. PLoS Biol 2013; 11: e1001647. https://doi.org/10.1371/journal.pbio.1001647
  5. Zhu X, Li Q, Chang R, Yang D, Song Z, Guo Q, et al. Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model. PLoS One 2014; 9: e91303. https://doi.org/10.1371/journal.pone.0091303

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