References
- Al-Dosari, M., and Alkuraya, F.S. (2009). A novel missense mutation in SCYL1BP1 produces geroderma osteodysplastica phenotype indistinguishable from that caused by nullimorphic mutations. Am. J. Med. Genet. A 149A, 2093-2098. https://doi.org/10.1002/ajmg.a.32996
- Bartel, D.P. (2009). MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233. https://doi.org/10.1016/j.cell.2009.01.002
- Beas, A.O., Taupin, V., Teodorof, C., Nguyen, L.T., Garcia-Marcos, M., and Farquhar, M.G. (2012). Gas promotes EEA1 endosome maturation and shuts down proliferative signaling through interaction with GIV (Girdin). Mol. Biol. Cell 23, 4623-4634. https://doi.org/10.1091/mbc.E12-02-0133
- Bergeland, T., Haugen, L., Landsverk, O.J., Stenmark, H., and Bakke, O. (2008). Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1. EMBO Rep. 9, 171-178. https://doi.org/10.1038/sj.embor.7401152
- Birkbak, N.J., Kochupurakkal, B., Izarzugaza, J.M., Eklund, A.C., Li, Y., Liu, J., Szallasi, Z., Matulonis, U.A., Richardson, A.L., Iglehart, J.D., et al. (2013). Tumor mutation burden forecasts outcome in ovarian cancer with BRCA1 or BRCA2 mutations. PLoS One 8, e80023. https://doi.org/10.1371/journal.pone.0080023
- Brooks, C.L., and Gu, W. (2006). p53 ubiquitination: Mdm2 and beyond. Mol. Cell 21, 307-315. https://doi.org/10.1016/j.molcel.2006.01.020
- Chen, L., Liu, R., Liu, Z.P., Li, M., and Aihara, K. (2012). Detecting early-warning signals for sudden deterioration of complex diseases by dynamical network biomarkers. Sci. Rep. 2, 342. https://doi.org/10.1038/srep00342
- Chen, Q.-L., Lu, Y.-Y., Zhang, G.-B., Song, Y.-N., Zhou, Q.-M., Hui Zhang, Zhang, W., and Su, S.-B. (2013a). Progression from excessive to deficient syndromes in chronic hepatitis B: adynamical network analysis of miRNA array data. Evid. Based Complement. Alternat. Med. 2013, 945245.
- Chen, Q.L., Lu, Y.Y., Zhang, G.B., Song, Y.N., Zhou, Q.M., Zhang, H., Zhang, W., Tang, X.S., and Su, S.B. (2013b). Characteristic analysis from excessive to deficient syndromes in hepatocarcinoma underlying miRNA array data. Evid. Based Complement. Alternat. Med. 2013, 324636.
- Di, Y., Li, J., Fang, J., Xu, Z., He, X., Zhang, F., Ling, J., Li, X., Xu, D., Li, L., et al. (2003). Cloning and characterization of a novel gene which encodes a protein interacting with the mitosis-associated kinase-like protein NTKL. J. Hum. Genet. 48, 315-321.
- Egawa, C., Miyoshi, Y., Takamura, Y., Taguchi, T., Tamaki, Y., and Noguchi, S. (2001). Decreased expression of BRCA2 mRNA predicts favorable response to docetaxel in breast cancer. Int. J. Cancer 95, 255-259. https://doi.org/10.1002/1097-0215(20010720)95:4<255::AID-IJC1043>3.0.CO;2-O
- Esquela-Kerscher, A., and Slack, F.J. (2006). Oncomirs - microRNAs with a role in cancer. Nat. Rev. Cancer 6, 259-269. https://doi.org/10.1038/nrc1840
- Forman, J.J., Legesse-Miller, A., and Coller, H.A. (2008). A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence. Proc. Natl. Acad. Sci. USA 105, 14879-14884. https://doi.org/10.1073/pnas.0803230105
- Guo, Y., Feng, Y., Trivedi, N.S., and Huang, S. (2011). Medusa structure of the gene regulatory network: dominance of transcription factors in cancer subtype classification. Exp. Biol. Med. (Maywood) 236, 628-636. https://doi.org/10.1258/ebm.2011.010324
- Hennies, H.C., Kornak, U., Zhang, H., Egerer, J., Zhang, X., Seifert, W., Kuhnisch, J., Budde, B., Natebus, M., Brancati, F., et al. (2008). Gerodermia osteodysplastica is caused by mutations in SCYL1BP1, a Rab-6 interacting golgin. Nat. Genet. 40, 1410-1412. https://doi.org/10.1038/ng.252
- Hou, J., Lin, L., Zhou, W., Wang, Z., Ding, G., Dong, Q., Qin, L., Wu, X., Zheng, Y., Yang, Y., et al. (2011). Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer Cell 19, 232-243. https://doi.org/10.1016/j.ccr.2011.01.001
- Hsu, S.D., Lin, F.M., Wu, W.Y., Liang, C., Huang, W.C., Chan, W.L., Tsai, W.T., Chen, G.Z., Lee, C.J., Chiu, C.M., et al. (2011). miRTarBase: a database curates experimentally validated microRNA-target interactions. Nucleic Acids Res. 39, D163-169. https://doi.org/10.1093/nar/gkq1107
- Huang da, W., Sherman, B.T., and Lempicki, R.A. (2009a). Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res. 37, 1-13. https://doi.org/10.1093/nar/gkn923
- Huang da, W., Sherman, B.T., and Lempicki, R.A. (2009b). Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57.
- Karami, F., and Mehdipour, P. (2013). A comprehensive focus on global spectrum of BRCA1 and BRCA2 mutations in breast cancer. Biomed. Res. Int. 2013, 928562.
- King, M.C., Marks, J.H., and Mandell, J.B. (2003). Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science 302, 643-646. https://doi.org/10.1126/science.1088759
- Krek, A., Grun, D., Poy, M.N., Wolf, R., Rosenberg, L., Epstein, E.J., MacMenamin, P., da Piedade, I., Gunsalus, K.C., Stoffel, M., et al. (2005). Combinatorial microRNA target predictions. Nat. Genet. 37, 495-500. https://doi.org/10.1038/ng1536
- Leng, R.P., Lin, Y., Ma, W., Wu, H., Lemmers, B., Chung, S., Parant, J.M., Lozano, G., Hakem, R., and Benchimol, S. (2003). Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell 112, 779-791. https://doi.org/10.1016/S0092-8674(03)00193-4
- Li, M., Vattulainen, S., Aho, J., Orcholski, M., Rojas, V., Yuan, K., Helenius, M., Taimen, P., Myllykangas, S., De Jesus Perez, V., et al. (2014). Loss of bone morphogenetic protein receptor 2 is associated with abnormal DNA repair in pulmonary arterial hypertension. Am. J. Respir. Cell Mol. Biol. 50, 1118-1128 https://doi.org/10.1165/rcmb.2013-0349OC
- Luo, T., Cui, S., Bian, C., and Yu, X. (2013). Crosstalk between TGFbeta/Smad3 and BMP/BMPR2 signaling pathways via miR-17-92 cluster in carotid artery restenosis. Mol. Cell. Biochem. 389, 169-176.
- Lytle, J.R., Yario, T.A., and Steitz, J.A. (2007). Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR. Proc. Natl. Acad. Sci. USA 104, 9667-9672. https://doi.org/10.1073/pnas.0703820104
- Magwood, A.C., Mundia, M.M., and Baker, M.D. (2012). High levels of wild-type BRCA2 suppress homologous recombination. J. Mol. Biol. 421, 38-53. https://doi.org/10.1016/j.jmb.2012.05.007
- Nepusz, T., Yu, H., and Paccanaro, A. (2012). Detecting overlapping protein complexes in protein-protein interaction networks. Nat. Methods 9, 471-472. https://doi.org/10.1038/nmeth.1938
- Norquist, B.M., Garcia, R.L., Allison, K.H., Jokinen, C.H., Kernochan, L.E., Pizzi, C.C., Barrow, B.J., Goff, B.A., and Swisher, E.M. (2010). The molecular pathogenesis of hereditary ovarian carcinoma: alterations in the tubal epithelium of women with BRCA1 and BRCA2 mutations. Cancer 116, 5261-5271. https://doi.org/10.1002/cncr.25439
- Poteryaev, D., Datta, S., Ackema, K., Zerial, M., and Spang, A. (2012). Identification of the switch in early-to-late endosome transition. Cell 141, 497-508.
- Ramanathan, H.N., and Ye, Y. (2012). The p97 ATPase associates with EEA1 to regulate the size of early endosomes. Cell Res. 22, 346-359. https://doi.org/10.1038/cr.2011.80
- Ramanathan, H.N., Zhang, G., and Ye, Y. (2013). Monoubiquitination of EEA1 regulates endosome fusion and trafficking. Cell Biosci. 3, 24. https://doi.org/10.1186/2045-3701-3-24
- Rytelewski, M., Ferguson, P.J., Maleki Vareki, S., Figueredo, R., Vincent, M., and Koropatnick, J. (2013). Inhibition of BRCA2 and thymidylate synthase creates multidrug sensitive tumor cells via the induction of combined "Complementary Lethality". Mol. Ther. Nucleic Acids 2, e78. https://doi.org/10.1038/mtna.2013.7
- Sawada, H., Saito, T., Nickel, N.P., Alastalo, T.P., Glotzbach, J.P., Chan, R., Haghighat, L., Fuchs, G., Januszyk, M., Cao, A., et al. (2014). Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension. J. Exp. Med. 211, 263-280. https://doi.org/10.1084/jem.20111741
- Shive, H.R., West, R.R., Embree, L.J., Golden, C.D., and Hickstein, D.D. (2014). brca2 and tp53 collaborate in tumorigenesis in zebrafish. PLoS One 9, e87177. https://doi.org/10.1371/journal.pone.0087177
- Spaziani, A., Alisi, A., Sanna, D., and Balsano, C. (2006). Role of p38 MAPK and RNA-dependent protein kinase (PKR) in hepatitis C virus core-dependent nuclear delocalization of cyclin B1. J. Biol. Chem. 281, 10983-10989. https://doi.org/10.1074/jbc.M512536200
- Stegh, A.H. (2013). Targeting the p53 signaling pathway in cancer therapy - the promises, challenges and perils. Exp. Opin. Ther. Targets 16, 67-83.
- van Iterson, M., Bervoets, S., de Meijer, E.J., Buermans, H.P., tHoen, P.A., Menezes, R.X., and Boer, J.M. (2013). Integrated analysis of microRNA and mRNA expression: adding biological significance to microRNA target predictions. Nucleic Acids Res. 41, e146. https://doi.org/10.1093/nar/gkt525
- Venkitaraman, A.R. (2002). Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 108, 171-182. https://doi.org/10.1016/S0092-8674(02)00615-3
- Vergoulis, T., Vlachos, I.S., Alexiou, P., Georgakilas, G., Maragkakis, M., Reczko, M., Gerangelos, S., Koziris, N., Dalamagas, T., and Hatzigeorgiou, A.G. (2012). TarBase 6.0: capturing the exponential growth of miRNA targets with experimental support. Nucleic Acids Res. 40, D222-229. https://doi.org/10.1093/nar/gkr1161
- Vlachos, I.S., Kostoulas, N., Vergoulis, T., Georgakilas, G., Reczko, M., Maragkakis, M., Paraskevopoulou, M.D., Prionidis, K., Dalamagas, T., and Hatzigeorgiou, A.G. (2012). DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways. Nucleic Acids Res. 40, W498-504. https://doi.org/10.1093/nar/gks494
- Xiao, F., Zuo, Z., Cai, G., Kang, S., Gao, X., and Li, T. (2009). miRecords: an integrated resource for microRNA-target interactions. Nucleic Acids Res. 37, D105-110. https://doi.org/10.1093/nar/gkn851
- Yan, J., Zhang, D., Di, Y., Shi, H., Rao, H., and Huo, K. (2010a). A newly identified Pirh2 substrate SCYL1-BP1 can bind to MDM2 and accelerate MDM2 self-ubiquitination. FEBS Lett. 584, 3275-3278. https://doi.org/10.1016/j.febslet.2010.06.027
- Yan, J., Di, Y., Shi, H., Rao, H., and Huo, K. (2010b). Overexpression of SCYL1-BP1 stabilizes functional p53 by suppressing MDM2-mediated ubiquitination. FEBS Lett. 584, 4319-4324. https://doi.org/10.1016/j.febslet.2010.09.019
- Yang, D., Khan, S., Sun, Y., Hess, K., Shmulevich, I., Sood, A.K., and Zhang, W. (2011). Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer. JAMA 306, 1557-1565. https://doi.org/10.1001/jama.2011.1456
- Zeng, Y., Qu, X., Li, H., Huang, S., Wang, S., Xu, Q., Lin, R., Han, Q., Li, J., and Zhao, R.C. (2012). MicroRNA-100 regulates osteogenic differentiation of human adipose-derived mesenchymal stem cells by targeting BMPR2. FEBS Lett. 586, 2375-2381. https://doi.org/10.1016/j.febslet.2012.05.049
- Zhang, L., Li, J., Wang, C., Ma, Y., and Huo, K. (2005). A new human gene hNTKL-BP1 interacts with hPirh2. Biochem. Biophys. Res. Commun. 330, 293-297. https://doi.org/10.1016/j.bbrc.2005.02.156
- Zheng, S., Tansey, W.P., Hiebert, S.W., and Zhao, Z. (2011). Integrative network analysis identifies key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma. BMC Med. Genomics 4, 62. https://doi.org/10.1186/1755-8794-4-62
Cited by
- The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage vol.11, pp.23, 2014, https://doi.org/10.18632/aging.102528