Asian Pacific Journal of Cancer Prevention

  • 제15권14호
  • /
  • Pages.5927-5936
  • /
  • 2014
  • /
  • 1513-7368(pISSN)
  • /
  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
권호 표지
DOI QR코드

DOI QR Code

Quality of Life and Psychological Well-Being of Breast Cancer Survivors in Jordan

  • 발행 : 2014.07.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Introduction: Breast cancer is the most common cancer among Jordanians. Breast cancer patients suffer from several negative consequences after treatment and these include pain, fatigue, sexual problems, appearance and body image concerns, with psychological dysfunction. This could affect the patient quality of life and psychological well-being. To the best of our knowledge, there is no published quantitative data on the quality of life and psychological well-being of breast cancer patients in Jordan. The objective of this study was to obtain such data and assess predictors with calculated scores. Methods: In this cross-sectional study conducted among breast cancer patients in Jordan diagnosed in 2009 and 2010, assessment was performed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), the Breast Module (QLQ-BR23) and the Hospital Anxiety and Depression Scale (HADS). Clinical, demographic and psychosocial indicators that could predict patient quality of life scores were collected. Results: The number of patients interviewed was 236 (mean age=$50.7{\pm}10.7$ years). The mean Global Health score for the QLQ-C30 was $63.7{\pm}20.2$ SD. Among functional scales, "social functioning" scored the highest ($mean=78.1{\pm}28.6$ SD), whereas "emotional functioning" scored the lowest ($mean=59.0{\pm}SD\;33.5$). For the QLQ-BR23, the worst scores within the functional scales were for "body image" ($mean=52.1{\pm}36.8$ SD) and "future perspective" ($mean=52.9{\pm}38.5$ SD). The worst symptom was "upset by hair loss" ($mean=69.8{\pm}43.0$). The mean HADS scores was $18.{\pm}9.0$ SD. Out of study participants, 53% scored abnormal on the anxiety scale and 45% on the depression scale. Severe depression and severe anxiety were detected among 8% and 14% of study participants, respectively. Statistically significant predictors for individual scores were similar to those reported in published studies, such as the presence of recurrence since baseline, family history of cancer, low educational status, current social problems, extent of the disease, presence of financial difficulties, and employment status. Conclusions and Recommendations: Breast cancer survivors in Jordan have overall good quality of life scores when compared with patients from Western countries. However, their psychological wellbeing is more impaired. There is an urgent need for psychosocial support programs and psychological screening and consultation for breast cancer patients at hospitals of the Ministry of Health in Jordan.

키워드

참고문헌

  1. Al-Subaihi AA (2003). Sample size determination. Influencing factors and calculation strategies for survey research. Saudi Med J, 4.
  2. Alawadi SA, Ohaeri JU (2009). Health-related quality of life of Kuwaiti women with breast cancer: a comparative study using the EORTC Quality of Life Questionnaire. BMC Cancer, 9, 222. https://doi.org/10.1186/1471-2407-9-222
  3. Arndt V, Merx H, Stegmaier C, Ziegler H, Brenner H (2005). Persistence of restrictions in quality of life from the first to the third year after diagnosis in women with breast cancer. J Clin Oncol, 23, 4945-53. https://doi.org/10.1200/JCO.2005.03.475
  4. Arndt V, Merx H, Sturmer T, et al. (2004). Age-specific detriments to quality of life among breast cancer patients one year after diagnosis. Eur J Cancer, 40, 673-80. https://doi.org/10.1016/j.ejca.2003.12.007
  5. Avis NE, Ip E, Foley KL (2006). Evaluation of the Quality of Life in Adult Cancer Survivors (QLACS) scale for long-term cancer survivors in a sample of breast cancer survivors. Health Qual Life Outcomes, 4, 92. https://doi.org/10.1186/1477-7525-4-92
  6. Awad MA, Denic S, El Taji H (2008). Validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaires for Arabic-speaking Populations. Ann New York Acad Sci, 1138, 146-54. https://doi.org/10.1196/annals.1414.021
  7. Bower JE, Ganz PA, Desmond KA, et al. (2006). Fatigue in long-term breast carcinoma survivors: a longitudinal investigation. Cancer, 751-8.
  8. Bower JE, Ganz PA, Desmond KA, et al. (2000). Fatigue in breast cancer survivors: occurrence, correlates, and impact on quality of life. J Clin Oncol, 18, 743-53.
  9. Bowling A (1991). Measuring Health: a Review of Quality of Life Measurement Scales. Buckingham: Open University Press.
  10. Bowling A (2001). Measuring Disease: a Review of Disease- Specific Quality of Life Measurement Scales: Springer- Verlag pp. 12-91.
  11. Brady MJ, Cella DF, Mo F, et al. (1997). Reliability and validity of the Functional Assessment of Cancer Therapy-Breast quality-of-life instrument. J Clin Oncol, 15, 974-86.
  12. Burgess C, Cornelius V, Love S, et al. (2005). Depression and anxiety in women with early breast cancer: five year observational cohort study. BMJ, 330, 702. https://doi.org/10.1136/bmj.38343.670868.D3
  13. El-Rufaie O, Absood G (1987). Validity study of the hospital anxiety and depression scale among a group of Saudi patients. Br J Psychiatry, 151, 687-8. https://doi.org/10.1192/bjp.151.5.687
  14. Ell K, Sanchez K, Vourlekis B, et al. (2005). Depression, correlates of depression, and receipt of depression care among low-income women with breast or gynecologic cancer. J Clin Oncol, 23, 3052-60. https://doi.org/10.1200/JCO.2005.08.041
  15. European Organization for Research and Treatment of Cancer. EORTC Quality of Life - Modules. from http://groups.eortc. be/qol/questionnaires_modules.htm
  16. Falk Dahl CA, Reinertsen KV, Nesvold IL, Fossa SD, Dahl AA (2010). A study of body image in long-term breast cancer survivors. Cancer, 116, 3549-57. https://doi.org/10.1002/cncr.25251
  17. Fallowfield L, Hall A, Maguire GP, Baum M (1990). Psychological outcomes in women with early breast cancer. BMJ, 301, 1394.
  18. Goldberg DW (2004). A User's guide to the General Health Questionnaire: Basingstoke NFER-Nelson.
  19. Gumus AB, Cam O, Malak AT (2011). Relationships between psychosocial adjustment and hopelessness in women with breast cancer. Asian Pac J Cancer Prev, 12, 433-8.
  20. Haghighat S, Akbari ME, Holakouei K, Rahimi A, Montazeri A (2003). Factors predicting fatigue in breast cancer patients. Supportive Care Cancer, 11, 533-8. https://doi.org/10.1007/s00520-003-0473-5
  21. Holzner B, Kemmler G, Kopp M, et al. (2001). Quality of life in breast cancer patients - not enough attention for long-term survivors? Psychosomatics, 42, 117-23. https://doi.org/10.1176/appi.psy.42.2.117
  22. Hopwood P, Haviland J, Mills J, Sumo G, M Bliss J (2007). The impact of age and clinical factors on quality of life in early breast cancer: an analysis of 2208 women recruited to the UK START Trial (Standardisation of Breast Radiotherapy Trial). The Breast, 16, 241-51. https://doi.org/10.1016/j.breast.2006.11.003
  23. Jassim GA, Whitford DL (2013). Quality of life of Bahraini women with breast cancer: a cross sectional study. BMC Cancer, 13, 212-. https://doi.org/10.1186/1471-2407-13-212
  24. Levine MN, Guyatt GH, Gent M, et al. (1988). Quality of life in stage II breast cancer: an instrument for clinical trials. J Clin Oncol, 6, 1798-810.
  25. Lueboonthavatchai P. (2007). Prevalence and psychosocial factors of anxiety and depression in breast cancer patients. J Med Assoc Thailand, 90, 2164.
  26. McDowell I. (2006). Measuring Health: a Guide to Rating Scales and Questionnaires: Oxford University Press.
  27. Mehnert A, Koch U (2008). Psychological comorbidity and health-related quality of life and its association with awareness, utilization, and need for psychosocial support in a cancer register-based sample of long-term breast cancer survivors. J Psychosomatic Res, 64, 383-91. https://doi.org/10.1016/j.jpsychores.2007.12.005
  28. Montazeri A, Vahdaninia M, Ebrahimi M, Jarvandi S (2003). The Hospital Anxiety and Depression Scale (HADS): translation and validation study of the Iranian version. Health Qual Life Outcomes, 1, 14. https://doi.org/10.1186/1477-7525-1-14
  29. Non-communicable Diseases Directorate MoH, Jordan (2013). Epidemiology and Survival Analysis of Jordanian Female Breast Cancer patients diagnosed during the period from 1997 to 2002.
  30. Non-communicable Diseases Directorate MoH, Jordan. Jordan Cancer Registry. (2011). Cancer incidence in Jordan; 2010.
  31. Northouse LL, Mood D, Kershaw T, et al. (2002). Quality of life of women with recurrent breast cancer and their family members. J Clin Oncol, 20, 4050-64. https://doi.org/10.1200/JCO.2002.02.054
  32. Oluka OC, Shi Y-Y, Nie S-F, Sun Y (2014). Boosting cancer survival in Nigeria: self-management strategies. Asian Pac J Cancer Prev, 15, 335-41. https://doi.org/10.7314/APJCP.2014.15.1.335
  33. Oztunc G, Yesil P, Paydas S, Erdogan S (2013). Social support and hopelessness in patients with breast cancer. Asian Pac J Cancer Prev, 14, 571-8. https://doi.org/10.7314/APJCP.2013.14.1.571
  34. Reich M, Lesur A, Perdrizet-Chevallier C (2008). Depression, quality of life and breast cancer: a review of the literature. Breast Cancer Res Treat, 110, 9-17. https://doi.org/10.1007/s10549-007-9706-5
  35. Souhami IT, Hohenberger P, Horiot JC (2001). Oxford Textbook of Oncology (2 ed.). Oxford: Oxford University Press.
  36. Sprangers MA, Groenvold M, Arraras JI, et al. (1996). The European Organization for Research and Treatment of Cancer breast cancer-specific quality-of-life questionnaire module: first results from a three-country field study. J Clin Oncol, 14, 2756-68.
  37. Sun M-Q, Meng A-F, Huang X-E, Wang M-X (2013). Comparison of psychological influence on breast cancer patients between breast-conserving surgery and modified radical mastectomy. Asian Pac J Cancer Prev, 14, 149-52. https://doi.org/10.7314/APJCP.2013.14.1.149
  38. Vahdaninia M, Omidvari S, Montazeri A (2010). What do predict anxiety and depression in breast cancer patients? A followup study. Social Psychiatry Psychiatric Epidemiology, 45, 355-61. https://doi.org/10.1007/s00127-009-0068-7
  39. Von Ah DM, Russell KM, Carpenter J, et al. (2012). Healthrelated quality of life of African American breast cancer survivors compared to healthy African American women. Cancer Nursing, 35, 337. https://doi.org/10.1097/NCC.0b013e3182393de3
  40. Waldmann A, Pritzkuleit R, Raspe H, Katalinic A (2007). The OVIS study: health related quality of life measured by the EORTC QLQ-C30 and -BR23 in German female patients with breast cancer from Schleswig-Holstein. Qual Life Res, 16, 767-76. https://doi.org/10.1007/s11136-006-9161-5
  41. Yavuzsen T, Karadibak D, Cehreli R, Dirioz M (2012). Effect of group therapy on psychological symptoms and quality of life in Turkish patients with breast cancer. Asian Pacific J Cancer Prev, 13, 5593-7. https://doi.org/10.7314/APJCP.2012.13.11.5593
  42. Zigmond AS, Snaith RP (1983). The hospital anxiety and depression scale. Acta Psychiatr Scand, 67, 361-70. https://doi.org/10.1111/j.1600-0447.1983.tb09716.x

피인용 문헌

  1. Anxiety, depression, perceived social support and quality of life in Malaysian breast cancer patients: a 1-year prospective study vol.13, pp.1, 2015, https://doi.org/10.1186/s12955-015-0401-7
  2. Associations among Physical Activity, Comorbidity, Functional Capacity, Peripheral Muscle Strength and Depression in Breast Cancer Survivors vol.16, pp.2, 2015, https://doi.org/10.7314/APJCP.2015.16.2.585
  3. Post-traumatic Stress Disorder and Post-traumatic Growth in Breast Cancer Patients - a Systematic Review vol.16, pp.2, 2015, https://doi.org/10.7314/APJCP.2015.16.2.641
  4. Cognitive Behavioral Therapy in Breast Cancer Patients - a Feasibility Study of an 8 Week Intervention for Tumor Associated Fatigue Treatment vol.16, pp.3, 2015, https://doi.org/10.7314/APJCP.2015.16.3.1063
  5. Relationships between Social Support and Social Image Concerns in Turkish Women with Breast Cancer vol.16, pp.5, 2015, https://doi.org/10.7314/APJCP.2015.16.5.1795
  6. Quality of life in Arab women with breast cancer: a review of the literature vol.14, pp.1, 2016, https://doi.org/10.1186/s12955-016-0468-9
  7. Rural Women's Awareness about Breast Cancer in Southeastern Iran: a Cross-Sectional Study vol.17, pp.4, 2016, https://doi.org/10.7314/APJCP.2016.17.4.1875
  8. Depression Moderates the Relationship between Body Image and Health-Related Quality of Life in Adolescent Girls vol.26, pp.7, 2017, https://doi.org/10.1007/s10826-017-0720-x
  9. Quality of Life in Women With Breast Cancer Treated With or Without Chemotherapy vol.40, pp.2, 2017, https://doi.org/10.1097/NCC.0000000000000370
  10. Quality of life of breast cancer survivors following breast-conserving therapy versus mastectomy: a multicenter study in Taiwan vol.47, pp.10, 2017, https://doi.org/10.1093/jjco/hyx099
  11. The effects on anxiety and quality of life of breast cancer patients following completion of the first cycle of chemotherapy vol.5, pp.2050-3121, 2017, https://doi.org/10.1177/2050312117717507
  12. Quality of life and anxiety in women with breast cancer before and after treatment vol.25, pp.0, 2017, https://doi.org/10.1590/1518-8345.2258.2958
  13. Home-Based Psychoeducational Intervention for Breast Cancer Survivors vol.41, pp.3, 2018, https://doi.org/10.1097/NCC.0000000000000483