Anxiety and mood (대한불안의학회지)

Korean Academy of Anxiety Disorders (대한불안의학회)
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Clinical Characteristics of Panic Disorder Patients in Korean University Hospital : A Multi-Center, Retrospective Study

국내 대학병원 공황장애 환자들의 임상적 특징에 대한 연구 : 다기관, 후향적 연구

  • Oh, Jae-Young (Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Jae-Hon (Seocho Mind-Health Clinic, Workplace Mental Health Institute, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Han, Sang-Woo (Department of Psychiatry, College of Medicine, Soonchunhyang University, Seoul Hospital) ;
  • Chee, Ik-Seung (Department of Psychiatry, School of Medicine, Chungnam National University) ;
  • Koo, Bon Hoon (Department of Psychiatry, College of Medicine, Yeungnam University) ;
  • Woo, Jong Min (Department of Psychiatry, Seoul Paik Hospital, Inje University College of Medicine) ;
  • Yang, Jong-Chul (Department of Psychiatry, Chonbuk National University Medical School) ;
  • Gim, Min-Sook (Department of Psychiatry, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Lee, Sang Hyuk (Department of Psychiatry, CHA Bundang Medical Center) ;
  • Heo, Jung-Yoon (Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Yu, Bum-Hee (Dr. Bum-Hee Yu's Psychiatric Clinic)
  • 오재영 (성균관대학교 의과대학 삼성서울병원 정신건강의학교실) ;
  • 이재헌 (성균관대학교 의과대학 강북삼성병원 건강의학본부 기업정신건강연구소) ;
  • 한상우 (순천향대학교 의과대학 서울병원 정신건강의학교실) ;
  • 지익성 (충남대학교 의학전문대학원 정신건강의학교실) ;
  • 구본훈 (영남대학교 의과대학 영남대학교병원 정신건강의학교실) ;
  • 우종민 (인제대학교 의과대학 서울백병원 정신건강의학교실) ;
  • 양종철 (전북대학교 의학전문대학원 정신건강의학교실) ;
  • 김민숙 (인제대학교 의과대학 상계백병원 정신건강의학교실) ;
  • 이상혁 (분당차병원 정신건강의학과) ;
  • 허정윤 (성균관대학교 의과대학 삼성서울병원 정신건강의학교실) ;
  • 유범희 (유범희 정신건강의학과 의원)
  • Received : 2013.11.08
  • Accepted : 2014.04.09
  • Published : 2014.04.30
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Abstract

Objective : Despite the high prevalence and clinical importance of panic disorder, studies on the clinical characteristics and course of panic disorder are relatively rare. This study is a multi-center, and retrospective study to examine the clinical characteristics and course of Korean panic disorder patients who visit university hospital. Methods : The study subjects were panic disorder patients who had visited the psychiatric outpatient clinics of 8 university hospitals in South Korea from January to December in 2008. Finally, 238 panic patients were included in this study. Their medical charts were retrospectively reviewed and reassessed by experienced psychiatrists to examine their clinical characteristics, demographic data and clinical course in repose to pharmacotherapy. Results : Among the 238 patients (121 males vs. 117 females), the mean age of disease onset was $41.3{\pm}12.7$ years and female patients showed 5 years older age of disease onset, compared with male patients. The mean score of PSR scale was $4.5{\pm}1.0$ at the first visit, reflecting a 'marked' level of severity of illness and impairment in functioning. Only 110 patients (46.4%) completed the whole follow up visits, whereas 128 patients (53.6%) dropped out during the treatment. After $17.7{\pm}0.5$ months of mean follow up period, the mean score of PSR scale at the last visit was reduced into $2.1{\pm}0.9$, reflecting a 'residual' severity of illness and impairment in functioning. The cumulative recovery rate was 62.1% in the completer group, whereas that of the drop-out group was 47.7%. Conclusions : The mean age of disease onset in Korean panic disorder patients who had visited university hospital was about 10 years older than that of Western panic disorder patients in previous studies, and the Korean panic disorder patients who had visited university hospital showed a relatively higher cumulative recovery rate. These differences might result from an ethnic difference in clinical characteristics and course in response to pharmacotherapy of panic disorder.

Keywords

References

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