Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
권호 표지

Seroprevalence of Swine Influenza Viruses H1N1 and H3N2 in Gyeongbuk Province, Korea

경북지역 돼지인플루엔자 바이러스(H1N1, H3N2) 항체조사

  • Accepted : 2014.04.10
  • Published : 2014.08.31
Download PDF
⟨ Previous Next ⟩

Abstract

Swine influenza is an acute respiratory disease prevalent in pig-growing areas worldwide. In total, 518 gilt and sow serum samples and 14 litters (66 samples) of aborted fetuses from 37 farms (average of 14 serum samples per farm) in Gyeongbuk Province were collected between September 2010 and May 2011. All samples were examined for antibodies to swine influenza virus (SIV) H1N1 and H3N2 using enzyme-linked immunosorbent assay (ELISA). The seropositive rates of gilt and sows were 59.8% (310/518) for SIV H1N1, 78.8% (408/518) for H3N2, and 55.6% (288/518) for both subtypes tested. The rate of aborted fetuses was 13.6% (9/66) for H1N1, 9.1% (6/66) for H3N2, and 9.1% for both subtypes. The seroprevalence for H1N1 in gilts and sows was 46.6% (69/148) and 65.1% (241/370), respectively, and that for H3N2 was 78.4% (116/148) and 78.9% (292/370), respectively.

Keywords

References

  1. 권준헌, 김병한, 탁동섭. 돼지 인플루엔자 바이러스 분리 및 혈청학적 역학조사. 대한수의학회지 1997; 37(부록3): 47-48.
  2. 김종란, 이재영, 송대섭, 오진식, 박봉균. 돼지인플루엔자바이러스 A형 H3 국내 분리주에 대한 혈청학적 역학조사. 대한수의학회지 2002; 42: 523-529.
  3. 류영수, 김로미. 돼지 인플루엔자 바이러스의 혈청학적 역학 조사 및 유전학적 분석. 대한수의학회지 1998; 38: 53-63.
  4. 윤재순, 박봉균, 한정희. 국내의 돼지인플루엔자 바이러스 (H1N1, H3N2)의 혈청학적 조사. 대한수의학회지 2007; 47: 273-279.
  5. 장은희, 하도윤, 박동엽, 이국천, 허정호. 경남지역내 돼지에 서의 swine influenza virus(H1N1, H3N2) 감염율 조사. 한국가축위생학회지 2011; 34: 195-200.
  6. 전용철, 양형석, 양나연, 김대용, 김재훈, 배종희. 제주지역 돼지에서 Ifluenza 바이러스 항원 및 혈중 항체 조사. 대한수의학회지 2004; 44: 449-454.
  7. 최정수, 김봉환. 영남지방 돼지의 주요 바이러스성 질병에 대한 혈청학적 역학조사. 대한수의학회지 1998; 38(부록3):117.
  8. Brown IH, Done SH, Spencer YI, Cooley WA, Harris PA, Alenxander DJ. Pathogenicity of a swine influenza H1N1 virus antigenically distinguishable from classical and European strains. Vet Rec 1993; 132: 598-602. https://doi.org/10.1136/vr.132.24.598
  9. Brown IH, Harris PA, McCauley JW, Alexander DJ. Multiple genetic reassortment of avian and human influenza A viruses in European pigs, resulting in the emergence of an H1N2 virus of novel genotype. J Gen Virol 1998; 79: 2947-2955. https://doi.org/10.1099/0022-1317-79-12-2947
  10. De Vleeschauwer A, Atanasova K, Van Borm S, van den Berg T, Rasmussen TB, Uttenthal A, Van Reeth K. Comparative pathogenesis of an avian H5N2 and a swine H1N1 influenza virus in pigs. PLoS One 2009; 17: e6662.
  11. Jeong K, Park YI, Jin W, Han JH. Seroprevalence of swine influenza and porcine reproductive and respiratory syndrome in Korea. Kor J Vet Serv 2007; 30: 197-203.
  12. Jung K, and Chae C. First outbreak of respiratory disease associated with swine influenza H1N2 virus in pigs in Korea. J Vet Diagn Investig 2005; 17: 176-178. https://doi.org/10.1177/104063870501700213
  13. Jung K, and Song DS. Evidence of the cocirculation of influenza H1N1, H1N2 and H3N2 viruses in the pig population of Korea. Vet Rec 2007; 16: 1104-1105.
  14. Jung K, Song DS, Kang BK, Oh JS, Park BK. Serologic surveillance of swine H1 and H3 and avian H5 and H9 influenza A virus infections in swine population in Korea. Prev Vet Med 2007; 79: 294-303. https://doi.org/10.1016/j.prevetmed.2006.12.005
  15. Jung T, Choi C, Chae C. Localization of swine influenza virus in naturally infected pigs. Vet Pathol 2002; 39: 10-16. https://doi.org/10.1354/vp.39-1-10
  16. Jung TW, Choi CS, Chung HK, Kim JH, Cho WS, Jung KI, Chae CH. Herd-level seroprevalence of swine-influenza virus in Korea. Pre Vet Med 2002; 53: 311-314. https://doi.org/10.1016/S0167-5877(01)00285-9
  17. Landolt GA, Olsen CW. Up to new tricks - a review of crossspecies transmission of influenza A viruses. Anim health Res Rev 2007; 8: 1-21. https://doi.org/10.1017/S1466252307001272
  18. Lee BW, Bey RF, Baarsch MJ, Morrison RB, Freese W. Determination of hemagglutination-inhibition titers to influenza A virus in porcine sera by use of an enzyme-linked immunosorbent assay. Am J Vet Res 1993; 54: 1270-1276.
  19. Leuwerke B, Kitikoon P, Evans R, Thacker E. Comparison of three serological assays to determine the cross-reactivity of antibodies from eight genetically diverse U.S. swine influenza virus. J Vet Diagn Invest 2008; 20: 426-432. https://doi.org/10.1177/104063870802000403
  20. Loeffen WLA, Heinen PP, Bianchi ATJ, Hunneman WA, Verheijden JHM. Effect of maternally derived antibodies on the clinical signs and immune response in pigs after primary and secondary infection with an influenza H1N1 virus. Vet Immunol Immunopathol 2003; 92: 23-35. https://doi.org/10.1016/S0165-2427(03)00019-9
  21. Loeffen WLA, Hunneman WA, Quak J, Verheijden JHM, Stegeman JA. Population dynamics of swine influenza virus in farrow-to-finish and specialised finishing herds in the Netherlands. Vet Microbiol 2009; 137: 45-50. https://doi.org/10.1016/j.vetmic.2009.01.004
  22. Loeffen WLA, Kamp EM, Stockhofe-Zurwieden N, Van Nieuwstadt APKMI, Bongers JH, Hunneman WA, Elbers ARW, Baars J, Nell T, Van Zijderveld FG. Survey of infectious agents involved in acute respiratory disease in finishing pigs. Vet Rec 1999; 145: 123-129. https://doi.org/10.1136/vr.145.5.123
  23. Lyoo YS, Park CK, Kim LM, Lee CH, Choi SH, Kim SI, Bae JH. Sero-epidemiology of the major swine infectious disease in Cheju. Korean J Vet Res 1997; 37: 765-772.
  24. Maldonado J, Van Reeth K, Riera P, SitjaM, Saubi N, Espuna E, Artigas C. Evidence of the concurrent circulation of H1N2, H1N1 and H3N2 influenza A viruses in densely populated pig areas in Spain. Vet J 2006; 172: 377-381. https://doi.org/10.1016/j.tvjl.2005.04.014
  25. Olsen CW, Carey S, Hinshaw L, Karasin AI. Virologic and serologic surveillance for human, swine and avian influenza virus infection among pigs in the north-central United States. Arch Virol 2000; 145: 1399-1419. https://doi.org/10.1007/s007050070098
  26. Shin JY, Song MS, Lee EH, Lee YM, Kim SY, Kim HK, Choi JK, Kim CJ, Webby RJ, Choi YK. Isolation and Characterization of Novel H3N1 Swine Influenza Viruses from Pigs with Respiratory Diseases in Korea. J Clin Microbiol 2006; 44: 3923-3927. https://doi.org/10.1128/JCM.00904-06
  27. Skibbe D, Zhou EM, Janke BH. Comparison of a commercial enzyme-linked immunosorbent assay with hemagglutination inhibition assay for serodiagnosis of swine influenza virus (H1N1) infection. J Vet Diagn Invest 2004; 16: 86-89. https://doi.org/10.1177/104063870401600116
  28. Song DS, Lee JY, Oh JS, Lyoo KS, Yoon KJ, Park YH, Park BK. Isolation of H3N2 swine influenza virus in South Korea. J Vet Diagn Invest 2003; 15: 30-34. https://doi.org/10.1177/104063870301500107
  29. Van Reeth K, Brown IH, Durrwaid R, Foni E, Labarque G, Lenihan P, Maldonado J, Markowska-Daniel I, Pensaert M, pospisil Z, Koch G. Seroprevalence of H1N1, H3N2 and H1N2 influenza virusea in pigs in seven European countries in 2002-2003.Influenza Other Respir Viruses 2008; 2: 99-105. https://doi.org/10.1111/j.1750-2659.2008.00043.x
  30. Van Reeth K, Brown IH, Olsen CW. Influenza virus. In: Diseases of swine, 10th ed. West Sussex, UK: John Wiley & Sons, Inc. 2012: 557-571.
  31. Yoon KJ, Janke BH, Swalla RW, Erickson G. Comparison of a commercial H1N1 enzyme-linked immunosorbent assay and hemmagglutination inhibition test in detecting serum antibody against swine influenza viruses. J Vet Diagn Invest 2004: 16: 197-201. https://doi.org/10.1177/104063870401600304