대한소아치과학회지 (Journal of the korean academy of Pediatric Dentistry)

  • 제41권3호
  • /
  • Pages.233-240
  • /
  • 2014
  • /
  • 1226-8496(pISSN)
  • /
  • 2288-3819(eISSN)
대한소아치과학회 (Korean Academy of Pediatric Dentistry)
권호 표지
DOI QR코드

DOI QR Code

Bovine teeth에 대한 어린이용 영양제의 우식유발능

Cariogenic Potential of Nutritional Supplements for Children on Bovine Teeth

  • 허나랑 (원광대학교 치과대학 소아치과학교실) ;
  • 이광희 (원광대학교 치과대학 소아치과학교실) ;
  • 안소연 (원광대학교 치과대학 소아치과학교실) ;
  • 송지현 (원광대학교 치과대학 소아치과학교실) ;
  • 라지영 (원광대학교 치과대학 소아치과학교실)
  • Heo, Narang (Department of Pediatric Dentistry, College of Dentistry, Wonkwang University) ;
  • Lee, Kwanghee (Department of Pediatric Dentistry, College of Dentistry, Wonkwang University) ;
  • An, Soyoun (Department of Pediatric Dentistry, College of Dentistry, Wonkwang University) ;
  • Song, Jihyun (Department of Pediatric Dentistry, College of Dentistry, Wonkwang University) ;
  • Ra, Jiyoung (Department of Pediatric Dentistry, College of Dentistry, Wonkwang University)
  • 투고 : 2014.04.24
  • 심사 : 2014.08.07
  • 발행 : 2014.08.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

어린이용 영양제의 우식 유발능에 관해 알아보기 위하여 국내에서 시판 중인 건강기능식품 어린이용 영양제 4종에 대한 생체외 연구를 시행하였다. 어린이용 영양제 4종을 실험군으로, 10% 자당을 양성 대조군, 인공 타액을 음성 대조군으로 하였다. 실험군 및 대조군의 pH, 완충능, 산생성능, 우치 법랑질 침식능을 검사하였다. 실험군 4종의 pH 모두 탈회 임계 pH인 5.5보다 낮았다. 완충능은 Hama Vitamin Pharm이 가장 크고, Smart Chewable Vitamin A가 가장 작았다. 4개의 실험군은 음성 대조군보다 유의하게 높은 산생성능을 보였다(p < 0.05). 우치 법랑질 침식능 검사 결과, 4종의 실험군과 양성 대조군에서 표면미세경도가 유의하게 감소하였다(p < 0.05). 표면미세경도 감소율은 실험군 중에서 Hama Vitamin Pharm이 유의하게 높았고, Hikid Plus는 유의하게 낮았다(p < 0.05).

An in vitro study on cariogenic potential of four over-the-counter nutritional supplements for children was performed. The experimental groups were four over-the-counter nutritional supplements. The positive control group was 10% sucrose solution (S), and the negative control group was artificial saliva (T). The pH of each group, the buffering capacities, acid production, the microhardness changes of the bovine teeth specimens were measured. The pH of all experimental groups were lower than critical pH 5.5 where enamel demineralization starts. The buffering capacity of the Hama Vitamin Pharm (Hamsoa Pharm Co., Korea) was highest, and the Smart Chewable Vitamin A (JW Pharm Co., Korea) had the lowest buffering capacity. The reduction rates of the pH of the experimental groups were significantly higher than that of the negative control group (p < 0.05). The microhardness of enamel of all experimental groups and the positive control group significantly decreased. In contrast, the microhardness of enamel of the negative control group significantly increased after experiment (p < 0.05). The reduction rate of the microhardness of enamel of the Hama Vitamin Pharm (Hamsoa Pharm Co., Korea) was significantly higher and Hikid Plus (Sanga Pharm Co., Korea) was significantly lower than the other experimental groups.

키워드

참고문헌

  1. Edelstein BL : Disparities in oral health and access to care : Findings of national surveys. Ambulatory Pediatrics, 2:141-147, 2002. https://doi.org/10.1367/1539-4409(2002)002<0141:DIOHAA>2.0.CO;2
  2. HEO SH : The present condition & development for labeling and advertising system of health functional food. Food Science and Industry, 40:11-15, 2007.
  3. Kim SH, Han JF, Kim WY : Consumption of health functional foods by elementary schoolchildren in Korea. Korean J Nutr, 43:161-170, 2010. https://doi.org/10.4163/kjn.2010.43.2.161
  4. Song BC, Kim MK : Patterns of vitamin-mineral supplement use among preschool children in Korea. Korean J Nutr, 31:1066-1075, 1998.
  5. Kim SH, Keen CL : Vitamin and mineral supplement use among children attending elementary schools in Korea : a survey of eating habits and dietary consequences. Nutrition Research, 22:433-448, 2002. https://doi.org/10.1016/S0271-5317(01)00322-0
  6. Park JS, Lee JH : Elementary school children's intake patterns of health functional foods and parent's requirements in Daejeon area. Korean J Nutr, 13:463-75, 2008.
  7. Kim SH, Han JH, Hwang YJ, Kim WY : Use of functional foods for health by 14-18 year old students attending general junior or senior high schools in Korea. Korean J Nutr, 38:864-72, 2005.
  8. Lingstrom P, van Ruyven FO, van Houte J, Kent R : The pH of dental plaque in its relation to early enamel caries and dental plaque flora in humans. J Dent Res, 79:770-777, 2000. https://doi.org/10.1177/00220345000790021101
  9. van Ruyven FO, Lingstrom P, van Houte J, Kent R : Relationship among mutans streptococci, "low-pH" bacteria, and lodophilic polysaccharide-producing bacteria in dental plaque and early enamel caries in humans. J Dent Res, 79:778-784, 2000. https://doi.org/10.1177/00220345000790021201
  10. van Houte J : Role of micro-organisms in caries etiology. J Dent Res, 7:672-681, 1994.
  11. Dibdin GH, Shellis RP : Physical and biochemical studies of Streptococcus mutans sediments suggest new factors linking the cariogenicity of plaque with its extracellular polysaccharide content. J Dent Res, 67:890-895, 1988. https://doi.org/10.1177/00220345880670060101
  12. Dodds MWJ, Edgar WM : Effects of dietary sucrose levels on pH fall and acid-anion profile in human dental plaque after a starch mouth-rinse. Archs Oral Biol, 31:509-512, 1986. https://doi.org/10.1016/0003-9969(86)90143-3
  13. Sgan-Cohen HD, Newbrun E, Sela MN, et al. : The effect of previous diet on plaque pH response to different foods. J Dent Res, 67:1434-1437, 1988. https://doi.org/10.1177/00220345880670111401
  14. Stephan RM : Intra-oral hydrogen-ion concentrations associated with dental caries activity. J Dent Res, 23:257-266, 1944. https://doi.org/10.1177/00220345440230040401
  15. Abelson DC, Mandel ID : The effect of saliva on plaque pH in vivo. J Dent Res, 60:1634-1638, 1981. https://doi.org/10.1177/00220345810600090101
  16. Kim JB, Paik DI, Kim DK, et al. : Clinical preventive dentistry, 4th ed., Komoonsa, Seoul, 314-315, 2005.
  17. Hase JC, Birkhed D, Lagerlof F, Thornqvist E : Oral retention of glucose at pharmacologically reduced salivary flow in man. Scand J Dent Res, 102:180-185, 1994.
  18. Yu KJ, Choi EG : An analytical study on the flow rate, viscosity, buffering capacity and inorganic composition of whole saliva. J Korean Acad Oral Health, 15:55-69, 1999.
  19. Shin HS, Lee KH, Kim YH, et al. : The effect of fermented milk on viable cell count and biofilm formation of Streptococcus mutans. J Korean Acad Pediatr Dent, 36:358-366, 2009.
  20. Lim HS, Lee KH, Kim YH, et al. : In vitro study on cariogenic potential of syrup-form medicines for children. J Korean Acad Pediatr Dent, 38:146-154, 2011. https://doi.org/10.5933/JKAPD.2011.38.2.146
  21. Hur YW, Kim SJ, Lee KH : In vitro study of baby food and breakfast cereal as for buffering capacity, acid production by Streptococcus mutans, and synthetic hydroxyapatite decalcification. J WonKwang Dent Res, 1:167-176, 1990.
  22. Loesche WJ : Role of Streptococcus mutans in human dental decay. Microbiol. Rev, 50:353-380, 1986.
  23. Aranibar QEM, Lingstrom P, Birkhed D : Influence of short-term sucrose exposure on plaque acidogenicity and cariogenic microflora in individuals with different levels of mutans streptococci. Caries Res, 37:51-57, 2003. https://doi.org/10.1159/000068221
  24. Korean Acad Pediatr Dent : Dentistry for the child and adolescent, 4th ed., Shin-hung international, Seoul, 173-174, 2007.
  25. Amaechi BT, Higham SM, Edgar WM : Techniques for the production of dental eroded lesions in vitro. J Oral Rehabil, 26:97-102, 1999. https://doi.org/10.1046/j.1365-2842.1999.00349.x
  26. Valinoti AC, Da Silva Pierro VS, Da Silva EM, et al. : In vitro alterations in dental enamel exposed to acidic medicines. Int J Paediatr Dent, 21:141-150, 2011. https://doi.org/10.1111/j.1365-263X.2010.01104.x
  27. Schilke R, Lisson JA, Geurtsen W, et al. : Comparison of the number and diameter of dentinal tubules in human and bovine dentine by scanning electron microscopic investigation. Archs Oral Biol, 45:355-361, 2000. https://doi.org/10.1016/S0003-9969(00)00006-6
  28. Camargo CHR, Siviero M, Valera MC, et al. : Topographical, diametral, and quantitative analysis of dentin tubules in the root canals of human and bovine teeth. J Endod, 33:422-426, 2007. https://doi.org/10.1016/j.joen.2006.12.011
  29. Camargo MA, Marques MMM, Cara AA : Morphological analysis of human and bovine dentine by scanning electron microscope investigation. Archs Oral Biology, 53:105-108, 2008. https://doi.org/10.1016/j.archoralbio.2007.09.005
  30. Zax MS, Mayer I, Deutsch D : Carbonate content in developing human and bovine enamel. J Dent Res, 70:913-916, 1991. https://doi.org/10.1177/00220345910700051001
  31. Ban MJ, Jang EJ, Jo NC, et al. : Sweetener content of common pediatric oral liquid and chewable tablet medications. J Korean Soc Hosp Pharm PP, 8:93-99, 1991.

피인용 문헌

  1. Comparison of Cariogenicity of Bovine Milk and Low-fat Milk on Streptococcus mutans Biofilm vol.44, pp.2, 2017, https://doi.org/10.5933/JKAPD.2017.44.2.170
  2. Anticariogenic Effects of Different Types of Tea vol.44, pp.4, 2017, https://doi.org/10.5933/JKAPD.2017.44.4.437