The Korean journal of internal medicine

  • 제29권3호
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  • Pages.383-387
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  • 2014
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  • 1226-3303(pISSN)
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  • 2005-6648(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
권호 표지
DOI QR코드

DOI QR Code

Distant subcutaneous recurrence of a parathyroid carcinoma: abnormal uptakes in the $^{99m}Tc$-sestamibi scan and $^{18}F$-FDG PET/CT imaging

  • Kim, Sang Soo (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Jeon, Yun Kyung (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Lee, Soo Hyung (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Kim, Bo Hyun (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Kim, Seong Jang (Department of Nuclear Medicine, Pusan National University School of Medicine) ;
  • Kim, Yong Ki (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Kim, In Ju (Department of Internal Medicine, Pusan National University School of Medicine)
  • 투고 : 2010.01.13
  • 심사 : 2010.08.19
  • 발행 : 2014.05.01
⟨ 이전 논문 다음 논문 ⟩

초록

We report a rare case of distant subcutaneous parathyroid carcinoma recurrence. A 50year-old woman was referred to our hospital because of sustained hypercalcemia despite surgical removal of a parathyroid carcinoma. A focal uptake in the upper mediastinal area was detected in a $^{99m}Tc$-sestamibi scan, and $^{18}F$-fluorodeoxyglucose (FDG) positron-emission tomography (PET)/computed tomography (CT) imaging demonstrated a subcutaneous mass. She underwent tumor resection, and the pathological findings were consistent with a parathyroid carcinoma. The postoperative serum parathyroid hormone (PTH) level remained within normal limits. However, a new palpable solitary mass was identified in the upper portion of the left breast 1 year postoperatively. Both a $^{99m}Tc$sestamibi scan and $^{18}F$-FDG PET/CT imaging revealed an abnormal lesion in the upper breast, and subsequent pathology reports confirmed parathyroid carcinoma metastasis. Serum PTH and calcium levels fell within normal ranges after tumor resection. Two subcutaneous recurrent lesions appeared likely due to tumor seeding during the previous endoscopic operation at a local hospital.

키워드

참고문헌

  1. Shane E. Clinical review 122: parathyroid carcinoma. J Clin Endocrinol Metab 2001;86:485-493. https://doi.org/10.1210/jcem.86.2.7207
  2. Yamamoto T, Matsumura A. Comment on "clinical review 122: parathyroid carcinoma". J Clin Endocrinol Metab 2001;86:5091.
  3. Rawat N, Khetan N, Williams DW, Baxter JN. Parathyroid carcinoma. Br J Surg 2005;92:1345-1353. https://doi.org/10.1002/bjs.5182
  4. Fernando R, Mettananda KC, Balasooriya BL, de Silva HJ. Subcutaneous local recurrence of parathyroid carcinoma. Ceylon Med J 2006;51:147.
  5. Kameyama K, Takami H. Double parathyroid carcinoma. Endocr J 2003;50:477-479. https://doi.org/10.1507/endocrj.50.477
  6. Assalia A, Inabnet WB. Endoscopic parathyroidectomy. Otolaryngol Clin North Am 2004;37:871-886. https://doi.org/10.1016/j.otc.2004.02.017
  7. Neumann DR, Esselstyn CB, Siciliano D, MacIntyre WJ, Kohse LM, Licata AA. Preoperative imaging of parathyroid carcinoma by positron emission tomography. Ann Otol Rhinol Laryngol 1994;103:741-745. https://doi.org/10.1177/000348949410300916
  8. Neumann DR, Esselstyn CB, Kim EY. Recurrent postoperative parathyroid carcinoma: FDG-PET and sestamibi- SPECT findings. J Nucl Med 1996;37:2000-2001.
  9. Grassetto G, Alavi A, Rubello D. PET and parathyroid. PET Clin 2007;2:385-393. https://doi.org/10.1016/j.cpet.2008.04.005
  10. Kebebew E, Arici C, Duh QY, Clark OH. Localization and reoperation results for persistent and recurrent parathyroid carcinoma. Arch Surg 2001;136:878-885. https://doi.org/10.1001/archsurg.136.8.878

피인용 문헌

  1. Parathyroid carcinoma with contralateral subcutaneous and breast recurrences: A rare presentation vol.38, pp.5, 2014, https://doi.org/10.1002/hed.24317
  2. Locoregional recurrence of parathyroid carcinoma: how to identify this rare but fatal condition using ultrasonography vol.68, pp.10, 2014, https://doi.org/10.1507/endocrj.ej21-0124
  3. The EANM practice guidelines for parathyroid imaging vol.48, pp.9, 2014, https://doi.org/10.1007/s00259-021-05334-y