Journal of the Korean Society of Radiology (한국방사선학회논문지)

The Korean Society of Radiology (한국방사선학회)
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The Study of Dosimetry according to the Thickness of Beam Spoiler on Total Body Irradiation

전신방사선치료시 산란체의 두께에 따른 선량측정

  • Kim, Youngjae (Dept. of Radiologic Technology, Daegu Health College) ;
  • Jeon, Byeongkyou (Dept. of Radiologic Technology, Daegu Health College) ;
  • Lee, Jaesik (Department of Clinical Laboratory Science, Hyejeon College) ;
  • Jung, Jaeeun (Dept. of Radiologic Technology, Daegu Health College)
  • 김영재 (대구보건대학교 방사선과) ;
  • 전병규 (대구보건대학교 방사선과) ;
  • 이재식 (혜전대학교 임상병리과) ;
  • 정재은 (대구보건대학교 방사선과)
  • Received : 2014.07.01
  • Accepted : 2014.08.26
  • Published : 2014.08.30
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Abstract

The therapy of total body irradiation on leukemia carries out to kill harmful bacteria or suppression of immune system by external beam therapy, which is a preparatory stage to reconstitute bone marrow before a pre-treatment of bone marrow transplantation to patients with health bone marrow cells. In case of this kind of radiation therapy, the spoiler use to increase surface dose of patient which varies depending on distance and thickness between patient and spoiler. In this study, the change was investigated the surface dose according to thickness of spoiler. The 0.5% increase of surface dose was observed with each 2.0 cm when the spioler in acrylic was prepared from 0.5 cm to 3.0 cm at intervals of 0.5 cm was evaluated. Based on this result, it suggests that this kind of application will be somewhat limited on clinical trials directly but proper surface dose can be useful method when is applied on patients of treatment prognosis who are required each different surface dose.

방사선을 이용한 백혈병의 전신방사선 치료는 환자의 골수에 건강한 골수세포를 이식하는 골수이식(bone marrow transplantation) 시행 전, 골수의 재구성을 위한 준비단계로 전신에 외부 방사선을 조사(external beam therapy)하여 유해한 세포를 죽이거나 면역체계의 억제를 목적으로 시행된다. 전신방사선 치료를 시행할 경우 환자의 표면선량을 증가하기 위해 사용되는 산란판(spoiler)을 사용하게 되는데 산란판을 사용할 때의 표면선량은 환자와의 거리에 따라 달라지고, 두께에 따라 달라지게 된다. 이에 본 논문에서는 산란판의 두께에 따른 표면선량의 변화를 알아보았다. 아크릴로 된 산란판을 0.5 cm부터 3.0 cm 까지 0.5 cm 간격으로 제작하여 각각 측정한 결과 2.0 cm를 기준으로 두께에 따라 약 0.5% 정도의 표면선량의 증가를 관찰 할 수 있었다. 이를 토대로 임상에 직접 적용하기에는 제한적일 수 있으나 임상실험과 치료받은 환자의 예후 등을 조사하여 임상에 적용한다면 각기 다른 표면선량을 요구하는 환자들에게 산란판의 두께변화 만으로도 적절한 표면선량을 부여하는 방법이 될 것으로 생각된다.

Keywords

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