참고문헌
- Alverts, A. W. : Discovery, biochemistry and biology of lovastatin. Am. J. Cardiol., 62, J10 (1998).
- Manzoni, M. and Rollini, M. : Biosynthesis and biotechnological production of statins by filamentous fungi and application of these cholesterol-lowering drugs. Appl. Microbiol. Biotechnol. 58, 555 (2002). https://doi.org/10.1007/s00253-002-0932-9
- Corsini, A., Bellosta, S., Baetta, R., Fumagalli, R., Paoletti, R. and Bernini, F. : New insights into the pharmacodynamic and pharmacokinetic properties of statins. Pharmacol. Ther. 84, 413 (1999). https://doi.org/10.1016/S0163-7258(99)00045-5
- Shitara, Y. and Sugiyama, Y. : Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions. Pharmacol. Ther. 112, 71 (2006). https://doi.org/10.1016/j.pharmthera.2006.03.003
- Chuengsamarn, S., Rattanamongkoulgul, S., Suwanwalaikorn, S., Wattanasirichaigoon, S. and Kaufman, L. : Effects of statins vs. non-statin lipid-lowering therapy on bone formation and bone mineral density biomarkers in patients with hyperlipidemia. Bone 46, 1011 (2010). https://doi.org/10.1016/j.bone.2009.12.023
- Xia, Z., Tan, M. M., Wei-Lynn Wong, W., Dimitroulakos, J., Minden, M. D. and Penn, L. Z. : Blocking protein prenylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells. Leukemia 15, 1398 (2001). https://doi.org/10.1038/sj.leu.2402196
- Jacobs, R. J., Voorneveld, P. W., Kodach, L. L. and Hardwick, J. C. H. : Cholesterol metabolism and colorectal cancers. Current Opinion Pharmacol. 12, 690 (2012). https://doi.org/10.1016/j.coph.2012.07.010
- Gauthaman, K., Fong, C. Y. and Bongso, A. : Statins, stem cells, and cancer, J. Cell. Biochem. 106, 975 (2009). https://doi.org/10.1002/jcb.22092
- Silva, M. A., Swanson, A. C., Gandhi, P. J. and Tataronis, G. R. : Statin-related adverse events: A meta-analysis. Clin. Ther. 28, 26 (2006). https://doi.org/10.1016/j.clinthera.2006.01.005
- Wortmann, R. L., Tipping, R. W., Levine, J. G. and Melin, J. M. : Frequency of myopathy in patients receiving lovastatin. Am. J. Cardiol. 95, 983 (2005). https://doi.org/10.1016/j.amjcard.2004.12.042
- Bellosta, S., Paoletti, R. and Corsini, A. : Safety of statins: focus on clinical pharmacokinetics and drug interactions. Circulation 109, III50 (2004). https://doi.org/10.1161/01.CIR.0000116208.41269.75
-
Patel, R. P. and Patel, M. M. : Solid-state characterization and dissolution properties of lovastatin hydroxypropyl-
${\beta}$ -cyclodextrin inclusion complex. Pharm. Technol. 31, 72 (2007). - Suresh, G., Manjunath, K., Venkateswarlu, V. and Satyanarayana, V. : Preparation, characterization, and in vitro and in vivo evaluation of lovastatin solid lipid nanoparticles. AAPS Pharm. Sci. Technol. 8, E1 (2007).
-
Mehramizi, A., Asgari Monfared, E., Pourfarzib, M., Bayati, Kh., Dorkoosh, F. A. and Rafiee-Tehrani, M. : Influence of
${\beta}$ -cyclodextrin complexation on lovastatin release from osmotic pump tablets (OPT). DARU 15, 71 (2007). - Patel, M., Tekade, A., Gattani, S. and Surana, S. : Solubility enhancement of lovastatin by modified locust bean gum using solid dispersion techniques, AAPS Pharm. Sci. Technol. 9, 1262 (2008). https://doi.org/10.1208/s12249-008-9171-4
- Wu, C., Wang, Z., Zhi, Z., Jiang, T., Zhang, J. and Wang, S. : Development of biodegradable porous starch foam for improving oral delivery of poorly water soluble drugs. Int. J. Pharm. 403, 162 (2011). https://doi.org/10.1016/j.ijpharm.2010.09.040
- Chen, C. C., Tsai, T. H., Huang, Z. R. and Fang, J. Y. : Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: physicochemical characterization and pharmacokinetics. Eur. J. Pharm. Biopharm. 74, 474 (2010). https://doi.org/10.1016/j.ejpb.2009.12.008
- Chun, I. K. : Dissolution and duodenal permeation characteristics of lovastatin from bile salt solid dispersions. J. Kor. Pharm. Sci. 39, 97 (2009). https://doi.org/10.4333/KPS.2009.39.2.097
- Shinde, A. J., Paithane, M. B. and More, H. N. : Development and in vitro evaluation of transdermal patches of lovastatin as a antilipidemic drug. Int. Res. J. Pharm. 1, 113 (2010).
- Zawar, L. R., Bhandari, G. S. and Bari, S. B. : Formulation and evaluation of transdermal film of lovastatin. Res. J. Pharm. Biol. Chem. Sci. 2, 575 (2011).
- Sharma, S., Sharma, A., Arora, S. and Gupta, A. : Preparation, characterization, in vitro & in vivo evaluation of elastic liposomal formulation of lovastatin. J. Pharm. Res. 4, 4074 (2011).
- Sarvaiya, J. I., Kapse, G. K. and Tank, C. J. : Iontophoresis of micellar composition of lovastatin: study of affecting factors and in vitro permeation. J. Pharm. Res. 7, 327 (2013). https://doi.org/10.1016/j.jopr.2013.04.032
- Kumar, R. and Philip, A. : Modified transdermal technologies: breaking the barriers of drug permeation via the skin. Trop. J. Pharm. Res. 6, 633 (2007).
- Gwak, H. S. and Chun, I. K. : Effect of vehicles and penetration enhancers on the in vitro percutaneous absorption of tenoxicam through hairless mouse skin. Int. J. Pharm. 236, 57 (2002). https://doi.org/10.1016/S0378-5173(02)00009-1
- Lee, J. H. and Chun, I. K. : Effects of various vehicles and fatty acids on the skin permeation of lornoxicam. J. Pharm. Invest. 42, 235 (2012). https://doi.org/10.1007/s40005-012-0035-2
- Alvarez-Lueje, A., Pastine, J., Squella, J. A. and Nunez-Vergara, L. J. : Assessment of the hydrolytic degradation of lovastatin by HPLC. J. Chil. Chem. Soc. 50, 639 (2005).
- Yang, D. J. and Hwang, L. S. : Study on the conversion of three natural statins from lactone forms to their corresponding hydroxy acid forms and their determination in Pu-Erh tea. J. Chromatogr. A 1119, 277 (2006). https://doi.org/10.1016/j.chroma.2005.12.031
- Huang, Z., Xu, Y., Li, Y. and Wang, Y. : Conversion investigation for lovastatin and its derivatives by HPLC. J. Chromatogr. Sci. 48, 631 (2010). https://doi.org/10.1093/chromsci/48.8.631
- Lovastatin Tablets, The United States Pharmacopeia, Volume II, The United Book Press, Baltimore, pp. 2815-2817 (2009).
- Kligman, A. M. : Topical pharmacology and toxicology of dimethyl sulfoxide. J. Am. Med. Assoc. 193, 796 (1965). https://doi.org/10.1001/jama.1965.03090100042010
- Barry, B. W. : Dermatological Formulations: Percutaneous Absorption, Marcel Dekker, New York, pp. 49-94 (1983).
- Serajuddin, A. T., Ranadive, S. A. and Mahoney, E. M. : Relative lipophilicities, solubilities, and structure-pharmacological considerations of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors pravastatin, lovastatin, mevastatin, and simvastatin. J. Pharm. Sci. 80, 830 (1991). https://doi.org/10.1002/jps.2600800905
- Williams, A. C. and Barry, B. W. : Penetration enhancers. Adv. Drug Del. Rev. 56, 603 (2004). https://doi.org/10.1016/j.addr.2003.10.025
- Ganem-Quintanar, A., Lafforgue, C., Falson-Rieg, F. and Buri, P. : Evaluation of the transepidermal permeation of diethylene glycol monoethyl ether and skin water loss. Int. J. Pharm. 147, 165 (1997). https://doi.org/10.1016/S0378-5173(96)04809-0
- Mura, P., Faucci, M. T., Bramanti, G. and Corti, P. : Evaluation of transcutol as a clonazepam transdermal permeation enhancer from hydrophilic gel formulations. Eur. J. Pharm. Sci. 9, 365 (2000). https://doi.org/10.1016/S0928-0987(99)00075-5
- Hoelgaard, A., Mollgaard, B. and Baker, E. : Vehicle effect on topical drug delivery. IV. effect of N-methylpyrrolidone and polar lipids on percutaneous drug transport, Int. J. Pharm. 43, 233 (1988). https://doi.org/10.1016/0378-5173(88)90279-7
- Golden, G. M., McKie, J. E. and Potts, R. O. : Role of stratum corneum lipid fluidity in transdermal drug flux. J. Pharm. Sci. 76, 25 (1987). https://doi.org/10.1002/jps.2600760108
- Komata, Y., Kaneko, A. and Fujie, T. : In vitro percutaneous absorption of thiamine disulfide through rat skin from a mixture of propylene glycol and fatty acid or its analog. Chem. Pharm. Bull. 40, 2173 (1992). https://doi.org/10.1248/cpb.40.2173
- Santoyo, S. and Ygartua P. : Effect of skin pretreatment with fatty acids on percutaneous absorption and skin retention of piroxicam after its topical application. Eur. J. Pharm. Biopharm. 50, 245 (2000). https://doi.org/10.1016/S0939-6411(00)00097-7
- Andega, S., Kanikkannan, N. and Singh, M. : Comparison of the effect of fatty alcohols on the permeation of melatonin between porcine and human skin. J. Controled Release 77, 17 (2001). https://doi.org/10.1016/S0168-3659(01)00439-4
- Oertel, R. P. : Protein conformational changes induced in human stratum corneum by organic sulfoxides: an infrared spectroscopic investigation. Biopolymers 16, 2329 (1977). https://doi.org/10.1002/bip.1977.360161017
- Roy, S. D., Hou, S.-Y. E., Witham, S. L. and Flynn, G. L. : Transdermal delivery of narcotic analgesics: comparative metabolism and permeability of human cadaver skin and hairless mouse skin. J. Pharm. Sci. 83, 1723 (1994). https://doi.org/10.1002/jps.2600831215
- Ghosh, B., Reddy, L. H., Kulkarni, R. V. and Khanam, J. : Comparison of skin permeability of drugs in mice and human cadaver skin. Indian J. Exp. Biol. 38, 42 (2000).
- Godin, B. and Touitou, E. : Transdermal skin delivery: predictions for humans from in vivo, ex vivo and animal models. Adv. Drug Del. Rev. 59, 1152 (2007). https://doi.org/10.1016/j.addr.2007.07.004