Pediatric Infection and Vaccine

The Korean Society of Pediatric Infectious Diseases (대한소아감염학회)
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Supraclavicular BCG Lymphadenitis Noted at 21 Months after BCG Vaccination Confirmed by a Molecular Method

분자생물학적 방법으로 확진한 접종 21개월 후에 발생한 BCG 쇄골상부 림프절염 1례

  • Lee, Min Hyun (Department of Pediatrics, Graduate School of Medicine, Gachon University) ;
  • Chae, Moon-Hee (Department of Pediatrics, Graduate School of Medicine, Gachon University) ;
  • Park, Kyoung Un (Department of Laboratory Medicine, Seoul National University Bundang Hospital) ;
  • Cho, Hye-Kyung (Department of Pediatrics, Graduate School of Medicine, Gachon University)
  • 이민현 (가천대학교 의학전문대학원 소아과학교실) ;
  • 채문희 (가천대학교 의학전문대학원 소아과학교실) ;
  • 박경운 (분당서울대학교병원 진단검사의학과) ;
  • 조혜경 (가천대학교 의학전문대학원 소아과학교실)
  • Received : 2013.09.15
  • Accepted : 2013.10.22
  • Published : 2014.08.25
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Abstract

Bacille Calmette-$Gu\acute{e}rin$ (BCG) lymphadenitis is the most common complication of BCG vaccination. It commonly occurs in infants aged <6 months involving ipsilateral axillary lymph nodes. We described BCG lymphadenitis in a 22-month-old boy presenting swelling of left supraclavicular lymph node that was confirmed by real-time polymerase chain reaction (PCR) and the multiplex PCR targeting the region of difference (RD).

BCG 림프절염은 BCG 접종 후에 생기는 가장 흔한 합병증이다. BCG 림프절염은 대부분 6개월 미만의 영아에서 발생하며 접종한 부위와 같은 쪽 겨드랑이 림프절을 침범하는 경우가 많다. 본 저자들은 생후 15일에 Tokyo주 BCG 백신을 접종한 22개월 남자아이에서 왼쪽 쇄골상부 림프절 부위에 발생한 BCG 림프절염을 경험하여 이에 대해 보고한다. 우리는 림프절 흡인을 시행하여 얻은 검체에서 실시간 중합효소 연쇄반응과 region of difference (RD)에 대한 다중 중합효소연쇄반응으로 M. bovis Tokyo주에 의한 감염을 확인하였고 반복적인 흡인을 통해 치료하였다.

Keywords

References

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