DOI QR코드

DOI QR Code

Surgical Decision Making for the Elderly Patients in Severe Head Injuries

  • Lee, Kyeong-Seok (Department of Neurosurgery, Soonchunhyang University Cheonan Hospital) ;
  • Shim, Jae-Jun (Department of Neurosurgery, Soonchunhyang University Cheonan Hospital) ;
  • Yoon, Seok-Man (Department of Neurosurgery, Soonchunhyang University Cheonan Hospital) ;
  • Oh, Jae-Sang (Department of Neurosurgery, Soonchunhyang University Cheonan Hospital) ;
  • Bae, Hack-Gun (Department of Neurosurgery, Soonchunhyang University Cheonan Hospital) ;
  • Doh, Jae-Won (Department of Neurosurgery, Soonchunhyang University Cheonan Hospital)
  • Received : 2013.10.01
  • Accepted : 2014.04.15
  • Published : 2014.04.28

Abstract

Objective : Age is a strong predictor of mortality in traumatic brain injuries. A surgical decision making is difficult especially for the elderly patients with severe head injuries. We studied so-called 'withholding a life-saving surgery' over a two year period at a university hospital. Methods : We collected data from 227 elderly patients. In 35 patients with Glasgow Coma Score 3--8, 28 patients had lesions that required operation. A life-saving surgery was withheld in 15 patients either by doctors and/or the families (Group A). Surgery was performed in 13 patients (Group B). We retrospectively examined the medical records and radiological findings of these 28 patients. We calculated the predicted probability of 6 month mortality (IPM) and 6 month unfavorable outcome (IPU) to compare the result of decision by the International Mission for Prognosis and Analysis of Clinical Trials in TBI (IMPACT) calculator. Results : Types of the mass lesion did not affect on the surgical decision making. None of the motor score 1 underwent surgery, while all patients with reactive pupils underwent surgery. Causes of injury or episodes of hypoxia/hypotension might have affected on the decision making, however, their role was not distinct. All patients in the group A died. In the group B, the outcome was unfavorable in 11 of 13 patients. Patients with high IPM or IPU were more common in group A than group B. Wrong decisions brought futile cares. Conclusion : Ethical training and developing decision-making skills are necessary including shared decision making.

Keywords

References

  1. Andrews PJ, Sleeman DH, Statham PF, McQuatt A, Corruble V, Jones PA, et al. : Predicting recovery in patients suffering from traumatic brain injury by using admission variables and physiological data : a comparison between decision tree analysis and logistic regression. J Neurosurg 97 : 326-336, 2002 https://doi.org/10.3171/jns.2002.97.2.0326
  2. Cagetti B, Cossu M, Pau A, Rivano C, Viale G : The outcome from acute subdural and epidural intracranial haematomas in very elderly patients. Br J Neurosurg 6 : 227-231, 1992 https://doi.org/10.3109/02688699209002930
  3. Chamoun RB, Robertson CS, Gopinath SP : Outcome in patients with blunt head trauma and a Glasgow Coma Scale score of 3 at presentation. J Neurosurg 111 : 683-687, 2009 https://doi.org/10.3171/2009.2.JNS08817
  4. Chaudhuri K, Malham GM, Rosenfeld JV : Survival of trauma patients with coma and bilateral fixed dilated pupils. Injury 40 : 28-32, 2009 https://doi.org/10.1016/j.injury.2008.09.004
  5. Frosch DL, Kaplan RM : Shared decision making in clinical medicine : past research and future directions. Am J Prev Med 17 : 285-294, 1999 https://doi.org/10.1016/S0749-3797(99)00097-5
  6. Hahm KH, Lee I : Biomedical ethics policy in Korea : characteristics and historical development. J Korean Med Sci 27 Suppl : S76-S81, 2012 https://doi.org/10.3346/jkms.2012.27.S.S76
  7. Honeybul S, Gillett GR, Ho KM, Lind CR : Neurotrauma and the rule of rescue. J Med Ethics 37 : 707-710, 2011 https://doi.org/10.1136/medethics-2011-100081
  8. Honeybul S, Ho K, O'Hanlon S : Access to reliable information about long-term prognosis influences clinical opinion on use of lifesaving intervention. PLoS One 7 : e32375, 2012 https://doi.org/10.1371/journal.pone.0032375
  9. Honeybul S, Ho KM, Lind CR, Gillett GR : Surgical intervention for severe head injury : ethical considerations when performing life-saving but non-restorative surgery. Acta Neurochir (Wien) 153 : 1105-1110, 2011 https://doi.org/10.1007/s00701-011-0974-9
  10. Honeybul S, O'Hanlon S, Ho KM : Decompressive craniectomy for severe head injury : does an outcome prediction model influence clinical decision-making? J Neurotrauma 28 : 13-19, 2011 https://doi.org/10.1089/neu.2010.1584
  11. Hukkelhoven CW, Steyerberg EW, Rampen AJ, Farace E, Habbema JD, Marshall LF, et al. : Patient age and outcome following severe traumatic brain injury : an analysis of 5600 patients. J Neurosurg 99 : 666-673, 2003 https://doi.org/10.3171/jns.2003.99.4.0666
  12. Kotwica Z, Saracen A : Severe head injuries in the elderly. Hygeia Public Health 45 : 197-201, 2010
  13. Kuhne CA, Ruchholtz S, Kaiser GM, Nast-Kolb D; Working Group on Multiple Trauma of the German Society of Trauma : Mortality in severely injured elderly trauma patients--when does age become a risk factor? World J Surg 29 : 1476-1482, 2005 https://doi.org/10.1007/s00268-005-7796-y
  14. Lingsma HF, Roozenbeek B, Steyerberg EW, Murray GD, Maas AI : Early prognosis in traumatic brain injury : from prophecies to predictions. Lancet Neurol 9 : 543-554, 2010 https://doi.org/10.1016/S1474-4422(10)70065-X
  15. Mak CH, Wong SK, Wong GK, Ng S, Wang KK, Lam PK, et al. : Traumatic brain injury in the elderly : is it as bad as we think? Curr Transl Geriatr Exp Gerontol Rep 1 : 171-178, 2012 https://doi.org/10.1007/s13670-012-0017-2
  16. MRC CRASH Trial Collaborators, Perel P, Arango M, Clayton T, Edwards P, Komolafe E, et al. : Predicting outcome after traumatic brain injury : practical prognostic models based on large cohort of international patients. BMJ 336 : 425-429, 2008 https://doi.org/10.1136/bmj.39461.643438.25
  17. Mushkudiani NA, Engel DC, Steyerberg EW, Butcher I, Lu J, Marmarou A, et al. : Prognostic value of demographic characteristics in traumatic brain injury : results from the IMPACT study. J Neurotrauma 24 : 259- 269, 2007 https://doi.org/10.1089/neu.2006.0028
  18. Patel HC, Bouamra O, Woodford M, Yates DW, Lecky FE : Clinical article : mortality associated with severe head injury in the elderly. Acta Neurochir (Wien) 152 : 1353-1357; discussion 1357, 2010 https://doi.org/10.1007/s00701-010-0666-x
  19. Pilitsis J, Atwater B, Warden D, Deck G, Carroll J, Smith J, et al. : Outcomes in octogenarians with subdural hematomas. Clin Neurol Neurosurg 115 : 1429-1432, 2013 https://doi.org/10.1016/j.clineuro.2013.01.017
  20. Rennie SC, van Rij AM, Jaye C, Hall KH : Defining decision making : a qualitative study of international experts' views on surgical trainee decision making. World J Surg 35 : 1214-1220, 2011 https://doi.org/10.1007/s00268-011-1089-4
  21. Schaller C, Kessler M : On the difficulty of neurosurgical end of life decisions. J Med Ethics 32 : 65-69, 2006 https://doi.org/10.1136/jme.2005.011767
  22. Steyerberg EW, Mushkudiani N, Perel P, Butcher I, Lu J, McHugh GS, et al. : Predicting outcome after traumatic brain injury : development and international validation of prognostic scores based on admission characteristics. PLoS Med 5 : e165; discussion e165, 2008 https://doi.org/10.1371/journal.pmed.0050165
  23. Stocchetti N, Paterno R, Citerio G, Beretta L, Colombo A : Traumatic brain injury in an aging population. J Neurotrauma 29 : 1119-1125, 2012 https://doi.org/10.1089/neu.2011.1995
  24. Tokutomi T, Miyagi T, Ogawa T, Ono J, Kawamata T, Sakamoto T, et al. : Age-associated increases in poor outcomes after traumatic brain injury : a report from the Japan Neurotrauma Data Bank. J Neurotrauma 25 : 1407-1414, 2008 https://doi.org/10.1089/neu.2008.0577
  25. Turgeon AF, Lauzier F, Simard JF, Scales DC, Burns KE, Moore L, et al. : Mortality associated with withdrawal of life-sustaining therapy for patients with severe traumatic brain injury : a Canadian multicentre cohort study. CMAJ 183 : 1581-1588, 2011 https://doi.org/10.1503/cmaj.101786