참고문헌
- Weycker, D., Macarios, D., Edelsberg, J. and Oster, G. (2007) Compliance with osteoporosis drug therapy and risk of fracture. Osteoporos. Int. 18, 271-277. https://doi.org/10.1007/s00198-006-0230-y
- Loi, A., Lisci, S., Denotti, A. and Cauli, A. (2013) Bone mineral density in women on long-term mud-bath therapy in a Salus per Aquam (SPA) environment. Reumatismo 65, 121-125.
- Barrett-Connor, E., Siris, E. S., Wehren, L. E., Miller, P. D., Abbott, T. A., Berger, M. L., Santora, A. C. and Sherwood, L. M. (2005) Osteoporosis and fracture risk in women of different ethnic groups. J. Bone Miner. Res. 20, 185-194.
- Lee, Y. H., Choi, S. J., Ji, J. D. and Song, G. G. (2012) Pathway analysis of genome-wide association study for bone mineral density. Mol. Biol. Rep. 39, 8099-8106. https://doi.org/10.1007/s11033-012-1657-1
- Wang, K., Li, M. and Hakonarson, H. (2010) Analysing biological pathways in genome-wide association studies. Nat. Rev. Genet., 11, 843-854. https://doi.org/10.1038/nrg2884
- Schadt, E. E. (2009) Molecular networks as sensors and drivers of common human diseases. Nature 461, 218-223. https://doi.org/10.1038/nature08454
- Low, Y. L., Li, Y., Humphreys, K., Thalamuthu, A., Li, Y., Darabi, H., Wedren, S., Bonnard, C., Czene, K., Iles, M. M., Heikkinen, T., Aittomaki, K., Blomqvist, C., Nevanlinna, H., Hall, P., Liu, E. T. and Liu, J. (2010) Multi-variant pathway association analysis reveals the importance of genetic determinants of estrogen metabolism in breast and endometrial cancer susceptibility. PLoS Genet. 6, e1001012. https://doi.org/10.1371/journal.pgen.1001012
- Fridley, B. L. and Biernacka, J. M. (2011) Gene set analysis of SNP data: benefits, challenges, and future Directions. Eur. J. Hum. Genet. 19, 837-843. https://doi.org/10.1038/ejhg.2011.57
- Nam, D., Kim, J., Kim, S. Y. and Kim, S. (2010) GSA-SNP: a general approach for gene set analysis of polymorphisms. Nucleic. Acids Res. 38, W749-754. https://doi.org/10.1093/nar/gkq428
- Zhang, L., Guo, Y. F., Liu, Y. Z., Liu, Y. J., Xiong, D. H., Liu, X. G., Wang, L., Yang, T. L., Lei, S. F., Guo, Y., Yan, H., Pei, Y. F., Zhang, F., Papasian, C. J., Recker, R. R. and Deng, H. W. (2010) Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD. J. Bone Miner. Res. 25, 1572-1580. https://doi.org/10.1002/jbmr.36
- Lee, Y. H., Choi, S. J., Ji, J. D. and Song, G. G. (2012) Pathway analysis of genome-wide association study for bone mineral density. Mol. Biol. Rep. 39, 8099-8106. https://doi.org/10.1007/s11033-012-1657-1
- Rose, E. C., Hagenmuller, M., Jonas, I. E. and Rahn, B. A. (2005) Validation of speed of sound for the assessment of cortical bone maturity. Eur. J. Orthod. 27, 190-195. https://doi.org/10.1093/ejo/cjh091
- Vanoevelen, J., Janssens, A., Huitema, L. F., Hammond, C. L., Metz, J. R., Flik, G., Voets, T. and Schulte-Merker, S. (2011) Trpv5/6 is vital for epithelial calcium uptake and bone formation. FASEB J. 25, 3197-3207. https://doi.org/10.1096/fj.11-183145
- Arai, F., Ohneda, O., Miyamoto, T., Zhang, X. Q. and Suda, T. (2002) Mesenchymal stem cells in perichondrium express activated leukocyte cell adhesion molecule and participate in bone marrow formation. J. Exp. Med. 195, 1549-1563. https://doi.org/10.1084/jem.20011700
- Sun, L., Adebanjo, O. A., Moonga, B. S., Corisdeo, S., Anandatheerthavarada, H. K., Biswas, G., Arakawa, T., Hakeda, Y., Koval, A., Sodam, B., Bevis, P. J., Moser, A. J., Lai, F. A., Epstein, S., Troen, B. R., Kumegawa, M. and Zaidi, M. (1999) CD38/ADP-ribosyl cyclase: A new role in the regulation of osteoclastic bone resorption. J. Cell Biol. 146, 1161-1172. https://doi.org/10.1083/jcb.146.5.1161
- Lecanda, F., Cheng, S. L., Shin, C. S., Davidson, M. K., Warlow, P., Avioli, L. V. and Civitelli, R. (2000) Differential regulation of cadherins by dexamethasone in human osteoblastic cells. J. Cell Biochem. 77, 499-506. https://doi.org/10.1002/(SICI)1097-4644(20000601)77:3<499::AID-JCB14>3.0.CO;2-0
- Greenblatt, M. B., Shim, J. H. and Glimcher, L. H. (2013) Mitogen-activated protein kinase pathways in osteoblasts. Annu. Rev. Cell Dev. Biol.
- Gartland, A., Skarratt, K. K., Hocking, L. J., Parsons, C., Stokes, L., Jorgensen, N. R., Fraser, W. D., Reid, D. M., Gallagher, J. A. and Wiley, J. S. (2012) Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women. Eur. J. Hum. Genet. 20, 559-564. https://doi.org/10.1038/ejhg.2011.245
- Bosetti, M., Leigheb, M., Brooks, R. A., Boccafoschi, F. and Cannas, M. F. (2010) Regulation of osteoblast and osteoclast functions by FGF-6. J. Cell Physiol. 225, 466-471. https://doi.org/10.1002/jcp.22225
- Eswarakumar, V. P., Monsonego-Ornan, E., Pines, M., Antonopoulou, I., Morriss-Kay, G. M. and Lonai, P. (2002) The IIIc alternative of Fgfr2 is a positive regulator of bone formation. Development 129, 3783-3793.
- Mocsai, A., Humphrey, M. B., Van Ziffle, J. A., Hu, Y., Burghardt, A., Spusta, S. C., Majumdar, S., Lanier, L. L., Lowell, C. A. and Nakamura, M. C. (2004) The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase. Proc. Natl. Acad. Sci. U. S. A. 101, 6158-6163. https://doi.org/10.1073/pnas.0401602101
- Abed, E. and Moreau, R. (2007) Importance of melastatin-like transient receptor potential 7 and cations (magnesium, calcium) in human osteoblast-like cell proliferation. Cell Prolif. 40, 849-865. https://doi.org/10.1111/j.1365-2184.2007.00476.x
- Cheng, H., Feng, J.M., Figueiredo, M.L., Zhang, H., Nelson, P.L., Marigo, V. and Beck, A. (2010) Transient receptor potential melastatin type 7 channel is critical for the survival of bone marrow derived mesenchymal stem cells. Stem Cells Dev. 19, 1393-1403. https://doi.org/10.1089/scd.2009.0262
- Mathews, S., Bhonde, R., Gupta, P.K. and Totey, S. (2012) Extracellular matrix protein mediated regulation of the osteoblast differentiation of bone marrow derived human mesenchymal stem cells. Differentiation 84, 185-192. https://doi.org/10.1016/j.diff.2012.05.001
- Boonrungsiman, S., Gentleman, E., Carzaniga, R., Evans, N. D., McComb, D. W., Porter, A. E. and Stevens, M. M. (2012) The role of intracellular calcium phosphate in osteoblast-mediated bone apatite formation. Proc. Natl. Acad. Sci. U. S. A. 109, 14170-14175. https://doi.org/10.1073/pnas.1208916109
- Blair, H. C., Schlesinger, P. H., Huang, C. L. and Zaidi, M. (2007) Calcium signalling and calcium transport in bone disease. Subcell Biochem. 45, 539-562. https://doi.org/10.1007/978-1-4020-6191-2_21
- Chellaiah, M. A., Soga, N., Swanson, S., McAllister, S., Alvarez, U., Wang, D., Dowdy, S. F. and Hruska, K. A. (2000) Rho-A is critical for osteoclast podosome organization, motility, and bone resorption. J. Biol. Chem. 275, 11993-12002. https://doi.org/10.1074/jbc.275.16.11993
- Mullin, B. H., Prince, R. L., Mamotte, C., Spector, T. D., Hart, D. J., Dudbridge, F. and Wilson, S. G. (2009) Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis. Bone 45, 387-391. https://doi.org/10.1016/j.bone.2009.04.254
- Jones, K. B., Mollano, A. V., Morcuende, J. A., Cooper, R. R. and Saltzman, C. L. (2004) Bone and brain: a review of neural, hormonal, and musculoskeletal connections. Iowa Orthop. J. 24, 123-132.
- Loskutova, N., Honea, R. A., Vidoni, E. D., Brooks, W. M. and Burns, J. M. (2009) Bone density and brain atrophy in early Alzheimer's disease. J. Alzheimers Dis. 18, 777-785. https://doi.org/10.3233/JAD-2009-1185
- Zhang, Y., Seshadri, S., Ellison, R. C., Heeren, T. and Felson, D. T. (2001) Bone mineral density and verbal memory impairment: Third National Health and Nutrition Examination Survey. Am. J. Epidemiol. 154, 795-802. https://doi.org/10.1093/aje/154.9.795
- Takito, J. and Nakamura, M. (2012) Precursors linked via the zipper-like structure or the filopodium during the secondary fusion of osteoclasts. Commun. Integr. Biol. 5, 453-457. https://doi.org/10.4161/cib.20980
-
Wei, Z. F., Tong, B., Xia, Y. F., Lu, Q., Chou, G. X., Wang, Z. T. and Dai, Y. (2013) Norisoboldine suppresses osteoclast differentiation through preventing the accumulation of TRAF6-TAK1 complexes and activation of MAPKs/NF-
${\kappa}B$ /c-Fos/NFATc1 Pathways. PLoS One 8, e59171. https://doi.org/10.1371/journal.pone.0059171 - Wan, L., Zou, W., Gao, D., Inuzuka, H., Fukushima, H., Berg, A. H., Drapp, R., Shaik, S., Hu, D., Lester, C., Eguren, M., Malumbres, M., Glimcher, L. H. and Wei, W. (2011) Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1. Mol. Cell 44, 721-733. https://doi.org/10.1016/j.molcel.2011.09.024
- Cho, Y. S., Go, M. J., Kim, Y. J., Heo, J. Y., Oh, J. H., Ban, H. J., Yoon, D., Lee, M. H., Kim, D. J., Park, M., Cha, S. H., Kim, J. W., Han, B. G., Min, H., Ahn, Y., Park, M. S., Han, H. R., Jang, H. Y., Cho, E. Y., Lee, J. E., Cho, N. H., Shin, C., Park, T., Park, J. W., Lee, J. K., Cardon, L., Clarke, G., McCarthy, M. I., Lee, J. Y., Lee, J. K., Oh, B. and Kim, H. L. (2009) A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat. Genet. 41, 527-534. https://doi.org/10.1038/ng.357
- Marchini, J., Howie, B., Myers, S., McVean, G. and Donnelly, P. (2007) A new multipoint method for genome-wide association studies by imputation of genotypes. Nat. Genet. 39, 906-913. https://doi.org/10.1038/ng2088