Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Endometrial Stromal Sarcoma Presented as an Incidental Lung Mass with Multiple Pulmonary Nodules

  • Kang, Dong Oh (Division of Pulmonology, Sleep and Critical Care Medicine, Department of Internal Medicine) ;
  • Choi, Sue In (Division of Pulmonology, Sleep and Critical Care Medicine, Department of Internal Medicine) ;
  • Oh, Jee Youn (Division of Pulmonology, Sleep and Critical Care Medicine, Department of Internal Medicine) ;
  • Sim, Jae Kyeom (Division of Pulmonology, Sleep and Critical Care Medicine, Department of Internal Medicine) ;
  • Choi, Jong Hyun (Division of Pulmonology, Sleep and Critical Care Medicine, Department of Internal Medicine) ;
  • Choo, Ji Yung (Department of Radiology, Korea University Ansan Hospital, Korea University College of Medicine) ;
  • Hwang, Jin Wook (Department of Thoracic and Cardiovascular Surgery, Korea University Ansan Hospital, Korea University College of Medicine) ;
  • Lee, Seung Heon (Division of Pulmonology, Sleep and Critical Care Medicine, Department of Internal Medicine) ;
  • Lee, Ju-Han (Department of Pathology, Korea University Ansan Hospital, Korea University College of Medicine) ;
  • Lee, Ki Yeol (Department of Radiology, Korea University Ansan Hospital, Korea University College of Medicine) ;
  • Shin, Chol (Division of Pulmonology, Sleep and Critical Care Medicine, Department of Internal Medicine) ;
  • Kim, Je Hyeong (Division of Pulmonology, Sleep and Critical Care Medicine, Department of Internal Medicine)
  • Received : 2013.10.02
  • Accepted : 2013.10.22
  • Published : 2014.03.30
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Abstract

Low-grade endometrial stromal sarcoma (ESS) is an uncommon gynecologic malignancy of mesodermal origin. Pulmonary metastasis of low-grade ESS can occur years and decades after the treatment of the primary disease. Low-grade ESS is frequently mistaken as benign uterine neoplasm like uterine leiomyoma, which can potentially lead to a misdiagnosis. We present a case of a 42-year-old woman with low-grade ESS, that initially presented as an incidental lung mass with multiple pulmonary nodules, seven years after an uterine myomectomy. A $6.9{\times}5.8cm-sized$ intrapelvic mass suspected of uterine origin was discovered while searching for potential extrathoracic primary origin. A pelviscopy and simultaneous thoracoscopic lung biopsy were conducted for pathologic diagnosis. Finally, the diagnosis was confirmed as low-grade ESS with lung metastasis based on the histopathologic examination with immunohistochemical stain, which was showed positive for CD10 and hormone receptor markers (estrogen and progesterone receptors) in both pelvic and lung specimens.

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References

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