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Collapsed L4 Vertebral Body Caused by Brucellosis

  • Ekici, Mehmet Ali (Department of Neurosurgery, Sevket Yilmaz Training and Research Hospital) ;
  • Ozbek, Zuhtu (Department of Neurosurgery, Yunus Emre State Hospital) ;
  • Kazanci, Burak (Department of Neurosurgery, Sevket Yilmaz Training and Research Hospital) ;
  • Guclu, Bulent (Department of Neurosurgery, Sevket Yilmaz Training and Research Hospital)
  • Received : 2012.06.23
  • Accepted : 2013.12.16
  • Published : 2014.01.28

Abstract

Brucellosis is caused by gram-negative, aerobic, non-motile, facultative, intracellular coccobacilli belonging to the genus Brucella. A 50-year-old man working as an employee was admitted to neurosurgery clinic with severe low back, radicular right leg pain and hypoesthesia in right L4-5 dermatomes for 2 months. Brucella tube agglutination (Wright) test was positive in serum sample of the patient with a titer of 1/640. Brucella melitensis was isolated from blood culture. X-ray and MRI of the lomber spine showed massive collapse of L4 vertebral body. Neural tissue was decompressed and then posterior L3-5 short segment transpedicular screw fixation and stabilization was performed. Brucella melitensis was isolated from microbiologic culture of pathologic specimen. Antibiotic therapy was given as doxycycline 200 mg/day and rifampicin 600 mg/day for 6 months. Brucellosis is a systemic zoonotic infection and still an important public health problem in many geographical parts of the world. Vertebral body collapse caused by brucellosis occurs very rarely but represents a neurosurgical emergency because of its potential for causing rapidly progressive spinal cord compression and permanent paralysis. Neurosurgeons, emergency department personnel as well as infectious disease specialists should always keep a high index of suspicion and include brucellosis in the differential diagnosis of vertebral body collapse.

Keywords

References

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