Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Goseki Grade and Tumour Location Influence Survival of Patients with Gastric Cancer

  • Calik, Muhammet (Department of Pathology, Faculty of Medicine, Ataturk University) ;
  • Calik, Ilknur (Department of Pathology, Education and Research Hospital) ;
  • Demirci, Elif (Department of Pathology, Faculty of Medicine, Ataturk University) ;
  • Altun, Eren (Department of Pathology, Faculty of Medicine, Ataturk University) ;
  • Gundogdu, Betul (Department of Pathology, Faculty of Medicine, Ataturk University) ;
  • Sipal, Sare (Department of Pathology, Faculty of Medicine, Ataturk University) ;
  • Gundogdu, Cemal (Department of Pathology, Faculty of Medicine, Ataturk University)
  • Published : 2014.02.01
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Abstract

Background: Owing to the variability of histopathological features and biological behaviour in gastric carcinoma, a great number of categorisation methods such as classical histopathologic grading, Lauren classification, the TNM staging system and the newly presented Goseki grading method are used by pathologists and other scientists. In our study, we aimed to investigate whether Goseki grade and tumour location have an effects on survival of gastric cancer cases. Materials and Methods: Eighty-four patients with gastric adenocarcinoma were covered in the investigation. The importance of Goseki grading system and tumour location were analysed in addition to the TNM staging and other conventional prognostic parameters. Results: The median survival time in our patients was 35 months (minimum: 5, maximum: 116). According to our findings, there was no relation between survival and tumour size (p=0.192) or classical histological type (p=0.270). In contrast, the Goseki grade and tumour location significantly correlated with survival (p=0.007 and p<0.001, respectively). Additionally, tumours of the intestinal type had a longer median survival time (60.0 months) than diffuse tumours (24.0 months). Conclusions: In addition to the TNM staging system, tumour location and the Goseki grading system may be used as significant prognostic parameters in patients with gastric cancer.

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References

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