Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Population Based Study of the Association Between Binge Drinking and Mortality from Cancer of Oropharynx and Esophagus in Korean Men: the Kangwha Cohort Study

  • Jung, Sang Hyuk (Department of Preventive Medicine, Ewha Womans University) ;
  • Gombojav, Bayasgalan (Institute for Health Promotion, Graduate School of Public Health, Yonsei University College of Medicine) ;
  • Park, Eun-Cheol (Department of Preventive Medicine, Yonsei University College of Medicine) ;
  • Nam, Chung Mo (Department of Preventive Medicine, Yonsei University College of Medicine) ;
  • Ohrr, Heechoul (Institute for Health Promotion, Graduate School of Public Health, Yonsei University College of Medicine) ;
  • Won, Jong Uk (Department of Preventive Medicine, Yonsei University College of Medicine)
  • Published : 2014.04.30
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Abstract

We assessed the association between frequency of heavy binge drinking and mortality from oropharynx and esophagus cancer after controlling for the total volume of alcohol intake among Korean men. The cohort comprised 2,677 male residents in Kangwha County, aged 55 or older in March 1985, for their upper digestive tract cancer mortality for 20.8 years up to December 31, 2005. For daily binge drinkers versus non-drinkers, the hazard ratios (95% Cls) for mortality were 4.82 (1.36, 17.1) and 6.75 (1.45, 31.4) for oropharyngeal and esophageal cancers, respectively. Even after adjusting for the volume of alcohol intake, we found the hazard ratios for frequency of binge drinking and mortality of oropharyngeal or esophageal cancer to not change appreciably: the hazard ratios were 4.90 (1.00, 27.0) and 7.17 (1.02, 50.6), respectively. For esophageal cancer, there was a strong dose-response relationship. The frequency of heavy binge drinking and not just the volume of alcohol intake may increase the risk of mortality from upper digestive tract cancer, particularly esophageal cancer in Korean men. These findings need to be confirmed in further studies with a larger sample size.

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References

  1. Bagnardi V, Blangiardo M, La Vecchia C, et al (2001). A metaanalysis of alcohol drinking and cancer risk. Br J Cancer, 85, 1700-5. https://doi.org/10.1054/bjoc.2001.2140
  2. Bongaerts BW, van den Brandt PA, Goldbohm RA, et al (2008). Alcohol consumption, type of alcoholic beverage and risk of colorectal cancer at specific subsites. Int J Cancer, 123, 2411-7. https://doi.org/10.1002/ijc.23774
  3. Centers for Disease Control and Prevention (CDC). (2004) Alcohol,attributable deaths and years of potential life lost,,United States, 2001. MMWR. Morbidity Mortaluty Weekly Report. 53, 866-70.
  4. Fan Y, Yuan JM, Wang R, et al (2008). Alcohol, tobacco, and diet in relation to esophageal cancer: the Shanghai Cohort Study. Nutr Cancer, 60, 354-63. https://doi.org/10.1080/01635580701883011
  5. Grønbaek M, Becker U, Johansen D, et al (1998). Population based cohort study of the association between alcohol intake and cancer of the upper digestive tract. Br Med J, 317, 844-7.
  6. Haas SL, Ye W, Lohr JM (2012). Alcohol consumption and digestive tract cancer. Curr Opin Clin Nutr, 15, 457-67. https://doi.org/10.1097/MCO.0b013e3283566699
  7. Homann N, Karkkainen P, Koivisto NT, et al (1997). Effects of acetaldehyde on cell regeneration and differentiation of the upper gastrointestinal tract mucosa. J Nat Cancer Inst, 89, 1692-7. https://doi.org/10.1093/jnci/89.22.1692
  8. Hong JS, Yi SW, Kang HC et al (2007). Body Mass Index and Mortality due to Cardiovascular Disease in South Korean Men: Kangwha Cohort Study. Ann Epidemiol, 17, 622-7. https://doi.org/10.1016/j.annepidem.2007.03.004
  9. Ishiguro S, Sasazuki S, Inoue M, et al (2009). Effect of alcohol consumption, cigarette smoking and flushing response on esophageal cancer risk: a population,based cohort study (JPHC study). Cancer Letters, 275, 240-6. https://doi.org/10.1016/j.canlet.2008.10.020
  10. Kim JS, Shukla SD (2006) Acute in vivo effect of ethanol (binge drinking) on histone H3 modifications in rat tissues. Alcohol and Alcoholism, 41, 126-32. https://doi.org/10.1093/alcalc/agh248
  11. La Vecchia C (2007). Alcohol and liver cancer. Eur J Cancer Prev, 16, 495-7. https://doi.org/10.1097/CEJ.0b013e3280145b5d
  12. Lee K, Lim HT, Hwang SS et al (2010). Socio-economic disparities in behavioural risk factors for cancer and use of cancer screening services in Korean adults aged 30 years and older: the Third Korean National Health and Nutrition Examination Survey, 2005 (KNHANES III). Public health, 124, 698-704. https://doi.org/10.1016/j.puhe.2010.07.004
  13. Malyutina S, Bobak M, Kurilovitch S et al (2002). Relation between heavy and binge drinking and all,cause and cardiovascular mortality in Novosibirsk, Russia: a prospective cohort study. Lancet, 360, 1448-54. https://doi.org/10.1016/S0140-6736(02)11470-X
  14. Ministry of Health and Welfare (2005) The Third Korea National Health and Nutrition Examination Survey (KNHANES III), 2005-Summary.
  15. Mokdad AH, Brewer RD, Naimi T et al (2007). Binge drinking is a problem that cannot be ignored. Prev Med, 44, 303-4. https://doi.org/10.1016/j.ypmed.2007.01.007
  16. Mørch LS, Johansen D, Thygesen LC et al (2007). Alcohol drinking, consumption patterns and breast cancer among Danish nurses: a cohort study. Eur J Pub Health, 17, 624-9. https://doi.org/10.1093/eurpub/ckm036
  17. Ohrr HC, Kim IS, Kim HO et al (1997). "Kangwha county cancer registry, Korea" in Cancer Incidence in five continents Vol. VII Parkin DM et al ed. IACR, IARC Scientific Publications No.143. Lyon 1997
  18. Ohrr HC, Yi SW, Sull JW (2002). "Kangwha county cancer registry, Korea" in Cancer Incidence in five continents Vol. VIII. Parkin DM et al ed. IACR, IARC Scientific Publications No.155. Lyon 2002
  19. Park BJ, Kim DS, Koo HW et al (1998). Reliability and validity study of a life style questionnaire for elderly people. Korean J Prev Med, 31, 49-58.
  20. Razvodovsky YE (2007). Alcohol poisoning and duodenum ulcer mortality in Russia, 1965-2005. Adicciones, 19, 423-31.
  21. Seitz HK, Poschl G, Simanowski UA (1998). Alcohol and cancer. Recent Dev Alcohol, 14, 67-95.
  22. Sull JW, Yi SW, Nam CM et al (2009). Binge drinking and mortality from all causes and cerebrovascular diseases in korean men and women: a Kangwha cohort study. Stroke, 40, 2953-8. https://doi.org/10.1161/STROKEAHA.109.556027
  23. Yaegashi Y, Onoda T, Morioka S et al (2014). Joint effects of smoking and alcohol drinking on esophageal cancer mortality in Japanese men: findings from the Japan collaborative cohort study. Asian Pac J Cancer Prev, 15, 1023-9. https://doi.org/10.7314/APJCP.2014.15.2.1023
  24. Yi SW, Sull JW, Linton JA, et al (2010). Alcohol consumption and digestive cancer mortality in Koreans: the Kangwha Cohort Study. J Epidemiol, 20, 204-11. https://doi.org/10.2188/jea.JE20090077

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