Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Preventive and Therapeutic Roles of Ginseng - Focus on Colon Cancer

  • Vayghan, Hamed Jafari (Student Research Committee, Tabriz University of Medical Sciences) ;
  • Ghadimi, Sevda Saleh (Student Research Committee, Tabriz University of Medical Sciences) ;
  • Nourazarian, Ali Reza (Department of clinical Biochemistry and Laboratory sciences, Tabriz University of Medical Sciences Aras International Branch)
  • Published : 2014.01.30
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Abstract

Colorectal cancer is one of the most prevalent diseases all over the world. Early screening and start of chemotherapy is effective in decreasing mortality. This type of cancer can be controlled to some extent via a healthy diet rich in fruit and vegetables. Ginseng is a plant which has been consumed as a herbal medicine for thousands of years in Asian countries. Several in vitro and in vivo studies have shown that this plant not only reduces the incidence of colorectal cancer, but also improves patient's status by enhancing the effects of chemotherapy drugs. However, further studies are needed to prove this relationship. We briefly review ginseng and its components such as ginsenosides reported anticancer effects and their mechanisms of action. Understanding these relationships may produce insights into chemical and pharmacological approaches for enhancing the chemo preventive effects of ginsenosides and for developing novel anticancer agents.

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References

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