Parasites, Hosts and Diseases

The Korea Society for Parasitology and Tropical Medicine (대한기생충학·열대의학회)
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Seroprevalence of Plasmodium vivax in the Republic of Korea (2003-2005) using Indirect Fluorescent Antibody Test

  • Kim, Tong-Soo (Department of Parasitology, College of Medicine, Inha University) ;
  • Kang, Yoon-Joong (Department of Biomedical Science, Jungwon University) ;
  • Lee, Won-Ja (Division of Malaria and Parasitic Diseases, National Institute of Health) ;
  • Na, Byoung-Kuk (Department of Parasitology and Institute of Health Sciences, Gyeongsang National University School of Medicine) ;
  • Moon, Sung-Ung (Department of International Medicine, Seoul National University, Bundang Hospital) ;
  • Cha, Seok Ho (Department of Biomedical Technology, Inha University School of Medicine) ;
  • Lee, Sung-Keun (Department of Pharmacology, Inha University School of Medicine) ;
  • Park, Yun-Kyu (Department of Parasitology, College of Medicine, Inha University) ;
  • Pak, Jhang-Ho (Asan Institute for Life Sciences, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Cho, Pyo Yun (Department of Parasitology, College of Medicine, Inha University) ;
  • Sohn, Youngjoo (Department of Anatomy, College of Korean Medicine, Institute of Korean Medicine, Kyung Hee University) ;
  • Lee, Hyeong-Woo (Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida)
  • Received : 2013.07.19
  • Accepted : 2013.09.16
  • Published : 2014.02.28
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Abstract

Plasmodium vivax reemerged in the Republic of Korea (ROK) in 1993, and is likely to continue to affect public health. The purpose of this study was to measure levels of anti-P. vivax antibodies using indirect fluorescent antibody test (IFAT) in border areas of ROK, to determine the seroprevalence of malaria (2003-2005) and to plan effective control strategies. Blood samples of the inhabitants in Gimpo-si, Paju-si, and Yeoncheon-gun (Gyeonggi-do), and Cheorwon-gun (Gangwon-do) were collected and kept in Korea Centers for Disease Control and Prevention (KCDC). Out of a total of 1,774 serum samples tested, the overall seropositivity was 0.94% (n=17). The seropositivity was the highest in Paju-si (1.9%, 7/372), followed by Gimpo-si (1.4%, 6/425), Yeoncheon-gun (0.67%, 3/451), and Cheorwon-gun (0.19%, 1/526). The annual parasite incidence (API) in these areas gradually decreased from 2003 to 2005 (1.69, 1.09, and 0.80 in 2003, 2004, and 2005, respectively). The highest API was found in Yeoncheon-gun, followed by Cheorwon-gun, Paju-si, and Gimpo-si. The API ranking in these areas did not change over the 3 years. The seropositivity of Gimpo-si showed a strong linear relationship with the API of 2005 (r=0.9983, P=0.036). Seropositivity data obtained using IFAT may be useful for understanding malaria prevalence of relevant years, predicting future transmission of malaria, and for establishing and evaluating malaria control programs in affected areas.

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References

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