Journal of the Korean Society of Manufacturing Process Engineers (한국기계가공학회지)

The Korean Society of Manufacturing Process Engineers (한국기계가공학회)
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Fabrication of a Polymeric Film with Nanofiber-based Porous Window and Its Application to Co-culture

섬유 기반의 다공성 윈도우를 가지는 박막 제작 및 공배양에의 활용

  • Jeong, Young Hun (School of Mechanical Engineering, Kyungpook National University) ;
  • Lee, Jongwan (School of Mechanical and Advanced Materials Engineering, UNIST) ;
  • Jin, Songwan (Department of Mechanical Engineering, Korea Polytechnic University)
  • Received : 2014.04.11
  • Accepted : 2014.04.24
  • Published : 2014.04.30
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Abstract

Recently, various biochip environments have been presented. In this study, a novel transparent film with porous membrane windows, which is an essential component in a co-cultured biochip environment, is fabricated using spin-coating, 3D printing, and electrospinning processes. In detail, a transparent polystyrene film was fabricated by means of the spin-coating process followed bywindow cutting, after which apolycaprolactone-chloroform solution was deposited along the window edge to introduce an adhesion layer between the PS film and the PCL nanofibers. Nanofibers were electrospun into the window region using a direct-write electrospinning method. Consequently, it was demonstrated that the fabricated window film could be used in a co-culture biochip environment.

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References

  1. Geschke. O., Klank. H., and Tellemann. P., Microsystem Engineering of Lab-on-a-Chip Devices, Wiley-VCH, 2004.
  2. Odian. G., Principles of Polymerization, Wiley-Interscience Publication, 2004.
  3. Sachs. E., Cima. M., Williams. P., Brancazio. D. and Cornie. J., "Three Dimensional Printing: Rapid Tooling and Prototypes Directly from a CAD Model" J. Manuf. Sci. Eng. Vol. 114 No. 4, pp. 481-488, 1992.
  4. Kruth. J.-P., Leu. M. C., and Nakagawa. T., "Progress in Additive Manufacturing and Rapid Prototyping" CIRP Annals-Manufacturing Technology Vol. 47 No. 2, pp. 525-540, 1998. https://doi.org/10.1016/S0007-8506(07)63240-5
  5. Baker. R., Membrane technology and applications, John Wiley & Sons, 2012.
  6. Steele. B. C., Heinzel. A., "Materials for Fuel-Cell Technologies" Nature ,Vol. 414, pp. 345-352, 2001. https://doi.org/10.1038/35104620
  7. Huh. D., Matthews. B. D., Mammoto. Akiko, Montoya-Zavala, M., Hsin. H. Y., and Ingber. D. E., "Reconstituting Organ-Level Lung Functions on a Chip" Science Vol 328 No. 5986, pp. 1662-1668, 2010. https://doi.org/10.1126/science.1188302
  8. Dzenis. Y., "Spinning continuous fibers for nanotechnology" Science Vol. 304 No. 5679, pp. 1917-1919, 2004. https://doi.org/10.1126/science.1099074
  9. Lu. X., Wang. C., Wei. Y., "One-Dimensional Composite Nanomaterials: Synthesis by Electrospinning and Their Applications" Small Vol. 5 No. 21, pp. 2349-2370, 2009. https://doi.org/10.1002/smll.200900445
  10. Lee. J. Lee. S. Y., Jang. J., Jeong. Y. H., and Cho. D.-W., "Fabrication of Patterned Nanofibrous Mats Using Direct-Write Electrospinning" Langmuir Vol. 28, pp. 7267-7275, 2012. https://doi.org/10.1021/la3009249

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  1. Multi-Nozzle Electrospinning Process to Fabricate Uniform Polymer Nanofiber Mats vol.17, pp.3, 2018, https://doi.org/10.14775/ksmpe.2018.17.3.120