디지털융복합연구 (Journal of Digital Convergence)

  • 제12권3호
  • /
  • Pages.367-375
  • /
  • 2014
  • /
  • 2713-6434(pISSN)
  • /
  • 2713-6442(eISSN)
한국디지털정책학회 (The Society of Digital Policy and Management)
권호 표지
DOI QR코드

DOI QR Code

흰쥐 미세구조 관찰을 위한 Micro-CT 3D 영상의 유용성에 관한 연구

A Study on the Usefulness of 3D Imaging in Micro-CT for Observing the Microstructure of Mice

  • 투고 : 2014.02.11
  • 심사 : 2014.03.20
  • 발행 : 2014.03.28
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

본 연구는 실시간 동적영상(Real-time dynamic image)을 획득할 수 있는 고해상도 엑스선 영상장치인 마이크로 CT 을 이용하여 흰쥐의 미세 혈관구조를 관찰함은 물론 국내 원광 방사선영상 과학연구 센터에서 개발한 마이크로 CT 에 대한 유용성을 알아보고자 한다. 흰쥐 몸 전체의 2D 영상을 얻은 후 MIP(maximum intensity projection), VRT(volume rendering technique)기법을 이용하여 혈관구조의 조영된 3D 영상을 얻을 수 있었고 이 3D 혈관 영상을 머리, 복부, 심장과 몸 전체의 혈관시스템으로 각각 분류하였다.

In this thesis we observe microvascular structure in mice by using micro-computed tomography (CT), which is high-resolution X-ray imaging equipment that can acquire Real-time dynamic image, and it aims to investigate the usefulness of micro-CT developed by Institute for Radiological Imaging Science Wonkwang University School of Medicine. After acquiring the systemic images of rats, contrast-enhanced 3D images of vascular structures could be acquired by using Maximum Intensity Projection (MIP) and Volume Rending Technique (VRT), This was divided into each vascular system of head, abdomen and heart and systemic vascular system.

키워드

참고문헌

  1. Seong-nae Kim; Understanding in-vivo micro-CT using the experimental animal model. Optoscan.
  2. Paciotti GF, Myer L, Weinreich D; Colloidal gold: anovel nanoparticle vector for tumor directed drug delivery. Drug Deliv. 2004, 11, 169-183. https://doi.org/10.1080/10717540490433895
  3. Su-yeol Lee & Sang-cheol Lee; Micro-topography for scanning small animals, Physics and Cutting-edge Techniques. 2004, November.
  4. Winter TCIII, Freeny PC, Nghiem HV;Hepatic arterial anatomy in transplantation candidates evaluation with three-dimensional CT arteriography. Radiology. 1995, 195, 363-370. https://doi.org/10.1148/radiology.195.2.7724754
  5. Takahashi S, Murakami T, Takamura M, Kim T, Hori M, Narumi Y, Nakamura H & Kudo M; Multi-detector row helical CT angiography of hepatic vessels; depiction with dual-arterial phase acquisition during single breath hold. Radiology. 2002, 222, 81-88. https://doi.org/10.1148/radiol.2221010326
  6. Ki-Yong Nam, Kwon-Ha Yoon; micro-CT System for Small animal imaging.
  7. Tae-jung Eom, Cheol Gang, Biophotonics imaging. Physics and Cutting-edge Techniques. 2007, June pp, 65-69.
  8. Bentley MD, Ortiz MC, Ritman EL & Romero JC; The use of micro-computed tomography to study micro-vasculature in small rodents. Am. J. Physiol Regul Integr Comp. Physiol. 2002, 282, F1267-79. https://doi.org/10.1152/ajpregu.00560.2001
  9. Gweon-ha Yoon & Gweon-su Cheon; X-ray optics and bio medical imaging. optical technique. 2006, Vol. 12, No. 1.
  10. Erik L. Ritman; Micro-Computed Tomography of the Lungs and Pulmonary-Vascular System. Proc. Am. Thorac. Soc. 2005, Vol 2, pp 477-480. https://doi.org/10.1513/pats.200508-080DS
  11. Garcia-Sanz A, Rodriguez-Barbero A, Bentley MD, Ritman EL & Romero JC; Three-dimensional micro-computed tomography of renal vasculature in mice. Hypertension. 1998, 31, 440-4. https://doi.org/10.1161/01.HYP.31.1.440
  12. Rubin GD, Dake MD & Napel S; Spiral CT of renal artery stenosi technique and resolution compared with conventional CT. AJR. Am. J. Roentgenol. 1994, 162, 561-567.s Comparison of three-dimensional rendering techniques. Radiology. 1994, 190,181-189. https://doi.org/10.1148/radiology.190.1.8259402
  13. Paranjpe DV & Bergin CJ; Spiral CT of the lungs Optimal https://doi.org/10.2214/ajr.162.3.8109496