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Anti-cancer and Anti-inflammatory Properties of Korean Citrus Fruits (Citrus aurantium L.)

  • Nagappan, Arulkumar (Research Institute of Life Science and College of Veterinary Medicine (BK21 plus project), Gyeongsang National University) ;
  • Park, Hyeon-Soo (Research Institute of Life Science and College of Veterinary Medicine (BK21 plus project), Gyeongsang National University) ;
  • Hong, Gyeong-Eun (Research Institute of Life Science and College of Veterinary Medicine (BK21 plus project), Gyeongsang National University) ;
  • Yumnam, Silvia (Research Institute of Life Science and College of Veterinary Medicine (BK21 plus project), Gyeongsang National University) ;
  • Lee, Ho-Jeong (Research Institute of Life Science and College of Veterinary Medicine (BK21 plus project), Gyeongsang National University) ;
  • Kim, Douk-Hoon (Department of Optometry, Masan University) ;
  • Kim, Eun-Hee (Department of Nursing Science, International University of Korea) ;
  • Kim, Gon-Sup (Research Institute of Life Science and College of Veterinary Medicine (BK21 plus project), Gyeongsang National University)
  • 투고 : 2014.01.21
  • 심사 : 2014.02.04
  • 발행 : 2014.03.31

초록

Purpose. Citrus aurantium L.(familyRutaceae), alsoknownasbitter orange, have been used as traditional herbal medicine in many Asian countries since ancient times. Hence, the purpose of the study was to briefly discuss the new findings about anti-inflammatory and anti-cancer activities of Citrus aurantium L in-vitro. Methods. The articles for this study were collected from pubmed and scopus electronic resources. Results. Citrus aurantium L contains an abundant Flavonoids, including hesperidin, naringin and nobiletin. These Flavonoids has reported to have various medicinal benefits that include antioxidant, antimicrobial, anti-inflammatory, anticancer, anti-diabetic activities, and also used to treat cardiovascular diseases. Conclusion. Based on the above evidence, we propose that Flavonoids from Korea Citrus aurantium L would be a therapeutic potential for cancer treatment and pharmacological benefit for inhibiting the inflammatory effect.

키워드

참고문헌

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