Korean Journal of Adult Nursing (성인간호학회지)

Korean Society of Adult Nursing (한국성인간호학회)
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Factors related to Quality of Life of Patients with Ulcerative Colitis

궤양성 대장염 환자의 삶의 질 영향요인

  • Received : 2013.07.11
  • Accepted : 2014.03.26
  • Published : 2014.04.30
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Abstract

Purpose: The purpose of this study was to identify factors related to the quality of life of patients with ulcerative colitis. Methods: A total 116 patients with ulcerative colitis were asked on general characteristics, illness-related characteristics, depression, and quality of life. The collected data were analyzed by t-test, ANOVA, and stepwise multiple regression. Results: As for depression the 81.03% were normal, the 8.62% were mild depression, the 6.90% were moderated depression, and the 3.45% were severe. As for quality of life, the social functions was highest, followed by intestine-related symptoms, systemic symptoms, and emotional functions. Quality of life was positively correlated to subjective health status, age, and body mass index, and negatively to depression. Main factors affecting the quality of life included depression, subjective health status, physician's global assessment, age, days of loss in social life, and present abdominal pain. Conclusion: Physical and psychosocial health problems related to ulcerative colitis affected the quality of life of the patients. Further research is warranted for developing educational programs and psychosocial strategies in order to efficiently handle the illness.

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References

  1. Ananthakrishnan, A. N., McGinley, E. L., & Binion, D. G. (2009). Inflammatory bowel disease in the elderly is associated with worse outcomes: A national study of hospitalizations. Inflammatory Bowel Disease, 15(2), 182-189. http://dx.doi.org/10.1002/ibd.20628
  2. Beck, A. T., Steer, R. A., & Brown, G. K. (1996). BDI-II, Beck depression inentory: Mannual (2nd ed). San Antonia, TX: Psychological Corporation.
  3. Boye, B., Jahnsen, J., Mokleby. K., Leganger, S., Jantschek, G., Jantschek, I., et al. (2008). The INSPIRE study: Are different personality traits related to disease-specific quality of life (IBDQ) in distressed patients with ulcerative colitis and Crohn's disease? Inflammatory Bowel Disease, 14 (5), 680-686. http://dx.doi.org/10.1002/ibd.20367
  4. Casellas, F., Arenas, J. I., Baudet, J. S., Fabregas, S., Garcia, N., Gelabert, J., et al. (2005). Impairment of health-related quality of life in patients with inflammatory bowel disease: A Spanish multicenter study. Inflammatory Bowel Disease, 11 (5), 488-496. https://doi.org/10.1097/01.MIB.0000159661.55028.56
  5. Cho, O. H., Yoo, Y. S., & Yang, S. K. (2012). Depression and risk factors in patients with Crohn's disease. Journal of Korean Academy of Nursing, 42 (2), 207-216. http://dx.doi.org/10.4040/jkan.2012.42.2.207
  6. Choi, C. H., Jung, S. A., Lee, B. I., Lee, K. M., Kim, J. S., & Han, D. S. (2009). Diagnostic guideline of ulcerative colitis. The Korean Journal of Gastroenterology, 53 (3), 145-160.
  7. Chung, G. E., Cheon, J. H., Lee, J. Y., Ye, B. D., Kim, S. G., & Kim, J. S. (2006). Efficacy of combination of intravenous cyclosporin A and steroid therapy versus prolonged intravenous steroid therapy alone in patients with severe ulcerative colitis refractory to initial intravenous steroid therapy. The Korean Journal of Gastroenterology, 48 (4), 263-268.
  8. D'Haens, G., Sandborn, W. J., Feagan, B. G., Geboes, K., Hanauer, S. B., Irvine, E. J., et al. (2007). A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis. Gastroenterology, 132 (2), 763-786. https://doi.org/10.1053/j.gastro.2006.12.038
  9. Faul, F., Erdfelder, E., Buchner, A., & Lang, A. G. (2009). Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses. Behavior Research Methods, 41, 1149-1160. http://dx.doi.org/10.3758/BRM.41.4.1149
  10. Fuller-Thomson, E., & Sulman, J. (2006). Depression and inflammatory bowel disease: Findings from two nationally representative Canadian surveys. Inflammatory Bowel Disease, 12 (8), 697-707. http://dx.doi.org/10.1097/00054725-200608000-00005
  11. Graff, L. A., Walker, J. R., & Bernstein, C. N. (2009). Depression and anxiety in inflammatory bowel disease: A review of cormobidity and management. Inflammatory Bowel Disease, 15 (7), 1105-1118. http://dx.doi.org/10.1002/ibd.20873
  12. Haapamaki, J., Roine, R. P., Turunen, U., Farkkila, M. A., & Arkkila, P. E. (2011). Increased risk for coronary heart disease, asthma, and connective tissue diseases in inflammatory bowel disease. Journal of Crohn's and Colitis, 5 (1), 41-47. http://dx.doi.org/10.1016/j.crohns.2010.09.008
  13. Han, S. W., McColl, E., Barton, J. R., James, P., Steen, I. N., & Welfare, M. R. (2005). Predictors of quality of life in ulcerative colitis: The importance of symptoms and illness representations. Inflammatory Bowel Disease, 11, 24-34. https://doi.org/10.1097/00054725-200501000-00004
  14. Hoivik, M. L., Moum, B., Solberg, I. C., Cvancarova, M., Hoie, O., Vatn, M. H., et al. (2012). Health-related quality of life in patients with ulcerative colitis after a 10-year disease course: Results from the IBSEN study. Inflammatory Bowel Disease, 18 (8), 1540-1549. http://dx.doi.org/10.1002/ibd.21863
  15. Irvine, E. J. (2008). Quality of life of patients with ulcerative colitis: Past, present and future. Inflammatory Bowel Disease, 14 (4), 554-565. https://doi.org/10.1002/ibd.20301
  16. Irvine, E. J., Zhou, Q., & Thompson, A. K. (1996). The Short Inflammatory Bowel Disease Questionnaire: A quality of life instrument for community physicians managing inflammatory bowel disease. CCRPT Investigators. Canadian Crohn's Relapse Prevention Trial. The American Journal of Gastroenterology, 91, 1571-1578.
  17. Kim, M. S., Lee, I. S., & Lee, C. S. (2007). The validation study I of Korean BDI-II: In female university students sample. The Korean Journal of Clinical Psychology, 26, 997-1014. https://doi.org/10.15842/kjcp.2007.26.4.011
  18. Korean Association for the Study of the Intestinal Diseases. (2003). Crohn's Disease. Seoul: Jin.
  19. Kornbluth, A., & Sachar, D. B. (2004). Ulcerative colitis practice guidelines in adults (update): American college of gastroenterology, practice parameters committee. The American Journal of Gastroenterology, 99 (7), 1371-1385. https://doi.org/10.1111/j.1572-0241.2004.40036.x
  20. Langhorst, J., Mueller, T., Luedtke, R., Franken, U., Paul, A., Michalsen, A., et al. (2007). Effects of a comprehensive lifestyle modification program on quality-of-life in patients with ulcerative colitis: A twelve-month follow-up. Scandinavian Journal of Gastroenterology, 42 (6), 734-745. https://doi.org/10.1080/00365520601101682
  21. Lee, J. H., Cheon, J. H., Moon, C. M., Park, J. J., Hong, S. P., Kim, T. I., et al. (2010). Do patients with ulcerative colitis diagnosed at a young age have more severe disease activity than patients diagnosed when older? Digestion, 81 (4), 237-243. http://dx.doi.org/10.1159/000253850
  22. Lix, L. M., Graff, L. A., Walker, J. R., Clara, I., Rawsthorne, P., Rogala, L., et al. (2008). Longitudinal study of quality of life and psychological functioning for active, fluctuating, and inactive disease patterns in inflammatory bowel disease. Inflammatory Bowel Disease, 14 (11), 1575-1584. http://dx.doi.org/10.1002/ibd.20511
  23. Mawdsley, J. E., & Rampton, D. S. (2005). Psychological stress in IBD: New insights into pathogenic and therapeutic implication. Gut, 54 (10), 1481-1491. https://doi.org/10.1136/gut.2005.064261
  24. Mittermaier, C., Dejaco, C., Waldhoer, T., Oefferlbauer-Ernst, A., Miehsler, W., Beier, M., et al. (2004). Impact of depressive mood on relapse in patients with inflammatory bowel disease: A prospective 18-month follow-up study. Psychosomatic Medicine, 66 (1), 79-84. http://dx.doi.org/10.1097/01.PSY.0000106907.24881.F2
  25. Moscandrew, M., Mahadevan, U., & Kane, S. (2009). General health maintenance in IBD. Inflammatory Bowel Diseases, 15 (9), 1399-1409. http://dx.doi.org/10.1002/ibd.20944
  26. Shin, I. S. (2005). The factors that influence the quality of life in cancer patients. Unpublished master's thesis, Kyung Hee University. Seoul.
  27. Tanaka, M., & Kazuma, K. (2005). Ulcerative colitis: Factors affecting difficulties of life and psychological well being of patients in remission. Journal of Clinical Nursing, 14 (1), 65-73. https://doi.org/10.1111/j.1365-2702.2004.00955.x
  28. Van der Eijk, I., Vlachonikolis, I. G., Munkholm, P., Nijman, J., Bernklev, T., Politi, P., et al. (2004). The role of quality of care in health-related quality of life in patients with IBD. Inflammatory Bowel Disease, 10 (4), 392-398. https://doi.org/10.1097/00054725-200407000-00010
  29. WHO/IASO/IOTF. (2000). The Asia-Pacific Perspective: Redefining Obesity and its Treatment. Health Communications Australia Pty Ltd. Retrieved February 10, 2014, from http://www.wpro.who.int/nutrition/documents/Redefining_obesity/en
  30. Yang, D. H., & Yang, S. K. (2009). Trends in the incidence of ulcerative colitis in Korea. Korean Journal of Medicine, 76 (6), 637-642.