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Cost-Effectiveness of Carotid Endarterectomy versus Carotid Artery Stenting for Treatment of Carotid Artery Stenosis

  • Kim, Jong Hun (Department of Thoracic and Cardiovascular Surgery, Chonbuk National University Medical School) ;
  • Choi, Jong Bum (Department of Thoracic and Cardiovascular Surgery, Chonbuk National University Medical School) ;
  • Park, Hyun Kyu (Department of Thoracic and Cardiovascular Surgery, Chonbuk National University Medical School) ;
  • Kim, Kyung Hwa (Department of Thoracic and Cardiovascular Surgery, Chonbuk National University Medical School) ;
  • Kuh, Ja Hong (Department of Thoracic and Cardiovascular Surgery, Chonbuk National University Medical School)
  • Received : 2013.07.15
  • Accepted : 2013.09.03
  • Published : 2014.02.05

Abstract

Background: Symptomatic or asymptomatic patients with significant carotid artery stenosis (range, 70% to 99%) generally undergo either carotid artery endarterectomy (CEA) or carotid artery stenting (CAS) to prevent stroke. In this study, we evaluated the cost effectiveness of these two treatment modalities. Methods: A total of 47 patients (mean age, $67.1{\pm}9.1$ years; male, 87.2%) undergoing either CEA (n=28) or CAS (n=19) for the treatment of significant carotid artery stenosis were enrolled in this study. Hospitalization costs were subdivided into three parts, namely pre-procedure, procedure and resource, and post-procedure costs. Results: Total hospitalization costs were similar in both groups of CEA and CAS (6,377 thousand won [TW] vs. 6,703 TW, p=0.255); however, the total cost minus the pre-procedure cost was higher in the CAS group than in the CEA group (4,948 TW vs. 5,941 TW, p<0.0001). The pre-procedure cost of the CEA group was higher than that of the CAS group (1,429 TW vs. 762 TW, p<0.0001). However, the procedure and resource cost was higher in the CAS group because the resource cost was approximately three times higher in the CAS group than in the CEA group. The post-procedure cost was higher in the CEA group because hospital stays were approximately two times longer. Conclusion: The total hospitalization cost was not different between the CEA and the CAS groups. The pre-procedure cost was high in the CEA group, but the cost from procedure onset to discharge, including the resource cost, was significantly lower in this group.

Keywords

References

  1. Inzitari D, Eliasziw M, Gates P, et al. The causes and risk of stroke in patients with asymptomatic internal-carotid- artery stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med 2000; 342:1693-700. https://doi.org/10.1056/NEJM200006083422302
  2. Eastcott HH, Pickering GW, Rob CG. Reconstruction of internal carotid artery in a patient with intermittent attacks of hemiplegia. Lancet 1954;267:994-6.
  3. Rothwell PM, Eliasziw M, Gutnikov SA, et al. Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis. Lancet 2003;361: 107-16. https://doi.org/10.1016/S0140-6736(03)12228-3
  4. Mas JL, Chatellier G, Beyssen B, et al. Endarterectomy versus stenting in patients with symptomatic severe carotid stenosis. N Engl J Med 2006;355:1660-71. https://doi.org/10.1056/NEJMoa061752
  5. SPACE Collaborative Group, Ringleb PA, Allenberg J, et al. 30 day results from the SPACE trial of stent-protected angioplasty versus carotid endarterectomy in symptomatic patients: a randomised non-inferiority trial. Lancet 2006;368: 1239-47. https://doi.org/10.1016/S0140-6736(06)69122-8
  6. Brott TG, Hobson RW 2nd, Howard G, et al. Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med 2010;363:11-23. https://doi.org/10.1056/NEJMoa0912321
  7. Janssen MP, de Borst GJ, Mali WP, et al. Carotid stenting versus carotid endarterectomy: evidence basis and cost implications. Eur J Vasc Endovasc Surg 2008;36:258-64. https://doi.org/10.1016/j.ejvs.2008.05.008
  8. Maud A, Vazquez G, Nyman JA, Lakshminarayan K, Anderson DC, Qureshi AI. Cost-effectiveness analysis of protected carotid artery stent placement versus endarterectomy in high-risk patients. J Endovasc Ther 2010;17:224-9. https://doi.org/10.1583/09-2938.1
  9. Pawaskar M, Satiani B, Balkrishnan R, Starr JE. Economic evaluation of carotid artery stenting versus carotid endarterectomy for the treatment of carotid artery stenosis. J Am Coll Surg 2007;205:413-9. https://doi.org/10.1016/j.jamcollsurg.2007.04.007
  10. North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 1991;325:445-53. https://doi.org/10.1056/NEJM199108153250701
  11. Kim TY, Choi JB, Kim KH, Kim MH, Shin BS, Park HK. Routine shunting is safe and reliable for cerebral perfusion during carotid endarterectomy in symptomatic carotid stenosis. Korean J Thorac Cardiovasc Surg 2012;45:95-100. https://doi.org/10.5090/kjtcs.2012.45.2.95
  12. Park B, Mavanur A, Dahn M, Menzoian J. Clinical outcomes and cost comparison of carotid artery angioplasty with stenting versus carotid endarterectomy. J Vasc Surg 2006;44:270-6. https://doi.org/10.1016/j.jvs.2006.04.049
  13. Sternbergh WC 3rd, Crenshaw GD, Bazan HA, Smith TA. Carotid endarterectomy is more cost-effective than carotid artery stenting. J Vasc Surg 2012;55:1623-8. https://doi.org/10.1016/j.jvs.2011.12.045
  14. Naylor AR. Occam's razor: intervene early to prevent more strokes! J Vasc Surg 2008;48:1053-9. https://doi.org/10.1016/j.jvs.2008.06.044

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