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Mediastinal Paraganglioma: Complete Resection Using Video-Assisted Thoracoscopic Surgery

  • Kim, Dohun (Department of Thoracic and Cardiovascular Surgery, Chungbuk National University College of Medicine) ;
  • Kim, Si-Wook (Department of Thoracic and Cardiovascular Surgery, Chungbuk National University College of Medicine) ;
  • Hong, Jong-Myeon (Department of Thoracic and Cardiovascular Surgery, Chungbuk National University College of Medicine)
  • Received : 2013.09.05
  • Accepted : 2013.10.01
  • Published : 2014.04.05

Abstract

Mediastinal paragangliomas are very rare neuroendocrine tumors. Complete resection is the standard treatment of a paraganglioma because of the tumor's potential malignancy and poor response to chemo- or radiotherapy. However, the highly vascular nature of the tumor and its characteristic anatomic location make complete resection difficult. We report a case of an anterior mediastinal paraganglioma, which was incidentally found on a chest computed tomography scan for chronic cough work-up of a 55-year-old woman. Complete resection was accomplished using video-assisted thoracoscopic surgery, and the patient recovered without any complications.

Keywords

References

  1. Eisenhofer G, Bornstein SR, Brouwers FM, et al. progress. Endocr Relat Cancer 2004;11:423-36. https://doi.org/10.1677/erc.1.00829
  2. Lamy AL, Fradet GJ, Luoma A, Nelems B. Anterior and middle mediastinum paraganglioma: complete resection is the treatment of choice. Ann Thorac Surg 1994;57:249-52. https://doi.org/10.1016/0003-4975(94)90419-7
  3. Paul S, Jain SH, Gallegos RP, Aranki SF, Bueno R. Functional paraganglioma of the middle mediastinum. Ann Thorac Surg 2007;83:e14-6. https://doi.org/10.1016/j.athoracsur.2007.02.090
  4. Andrade CF, Camargo SM, Zanchet M, Felicetti JC, Cardoso PF. Nonfunctioning paraganglioma of the aortopulmonary window. Ann Thorac Surg 2003;75:1950-1. https://doi.org/10.1016/S0003-4975(02)04841-5
  5. Shakir M, Blossom G, Lippert J. Anterior mediastinal paraganglioma: a case for preoperative embolization. World J Surg Oncol 2012;10:134. https://doi.org/10.1186/1477-7819-10-134
  6. Mitchell J, Siperstein A, Milas M, Berber E. Laparoscopic resection of abdominal paragangliomas. Surg Laparosc Endosc Percutan Tech 2011;21:e48-53. https://doi.org/10.1097/SLE.0b013e31820ad532
  7. Lin MW, Chang YL, Lee YC, Huang PM. Non-functional paraganglioma of the posterior mediastinum. Interact Cardiovasc Thorac Surg 2009;9:540-2. https://doi.org/10.1510/icvts.2009.206169
  8. Ayala-Ramirez M, Feng L, Johnson MM, et al. Clinical risk factors for malignancy and overall survival in patients with pheochromocytomas and sympathetic paragangliomas: primary tumor size and primary tumor location as prognostic indicators. J Clin Endocrinol Metab 2011;96:717-25. https://doi.org/10.1210/jc.2010-1946

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  1. Minimally invasive robotic-assisted excision of an aortopulmonary mediastinal paraganglioma vol.55, pp.5, 2019, https://doi.org/10.1093/ejcts/ezy334
  2. Primary endobronchial paraganglioma with lymph node metastasis: a case report vol.49, pp.3, 2021, https://doi.org/10.1177/03000605211003014