Journal of Chest Surgery

The Korean Society for Thoracic and Cardiovascular Surgery (대한심장혈관흉부외과학회)
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Massive Rhabdomyolysis Following Cardiopulmonary Bypass

  • Kim, Young Sam (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital, Inha University School of Medicine) ;
  • Yoon, Yong Han (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital, Inha University School of Medicine) ;
  • Kim, Joung Taek (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital, Inha University School of Medicine) ;
  • Baek, Wan Ki (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital, Inha University School of Medicine)
  • Received : 2013.05.15
  • Accepted : 2013.09.17
  • Published : 2014.04.05
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Abstract

Here, we report a case of massive rhabdomyolysis following an uncomplicated repair of a ventricular septal defect in a five-month-old baby. Postoperatively, the patient was hemodynamically stable but metabolic acidosis continued, accompanied by fever and delayed mental recovery. The next day, he became comatose and never regained consciousness thereafter. The computed tomography of the brain revealed a diffuse brain injury. The patient followed a downhill course and eventually died on postoperative day 33. An unusually high level of creatine phosphokinase was noticed, peaking (21,880 IU/L) on postoperative day 2, suggesting severe rhabdomyolysis. The relevant literature was reviewed, and the possibility of malignant hyperthermia obscured by cardiopulmonary bypass and hypothermia was addressed.

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References

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Cited by

  1. Almost-certain malignant hyperthermia during cardiopulmonary bypass: a case report and literature review vol.34, pp.6, 2014, https://doi.org/10.1177/0267659119833230