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Feasibility of Early and Repeated Low-dose Interscalene Brachial Plexus Block for Residual Pain in Acute Cervical Radiculopathy Treated with NSAIDS

  • Iwata, Toshio (Department of Anesthesiology, Nara Prefectural Mimuro Hospital) ;
  • Mitoro, Mari (Department of Anesthesiology, Nara Prefectural Mimuro Hospital) ;
  • Kuzumoto, Naoya (Department of Anesthesiology, Nara Prefectural Mimuro Hospital)
  • Received : 2013.09.24
  • Accepted : 2014.03.06
  • Published : 2014.04.01

Abstract

Background: To improve residual pain management in acute cervical radiculopathy treated with NSAIDs, the feasibility of early and repeated low-dose interscalene brachial plexus block (IS-BPB) needs to be assessed. Methods: This was a prospective study on patients receiving NSAIDs (loxoprofen) for cervical radiculopathy of ${\leq}2$-week onset. Pain was assessed using the visual analogue scale (VAS). A low-dose ultrasonography (USG)-guided IS-BPB (dexamethasone [1.65 mg; 0.5 ml] and mepivacaine [1%; 3.0 ml]) was performed at baseline and weekly thereafter for 4 weeks in an outpatient setting for the intervention group. All patients were evaluated using a visual satisfaction score (VSS) at week 4. Patients with baseline VAS scores < 70 (mild to moderate pain; MM group) and ${\geq}70$ (severe pain; SE group) were compared to the controls receiving NSAIDs. Results: A total of 316 IS-BPBs were performed in the intervention group. There was a significant difference in the decline in the VAS from week 0 to week 3 in the MM and SE groups (P < 0.05); however, from week 3 to week 4, the therapeutic effect exhibited no significant difference. Thirteen patients at week 2 (15.5%; MM: 27.7%; SE: 0%), 43 at week 3 (51.2%; MM: 83.0%; SE: 10.8%), and 47 at week 4 (56.0%; MM: 85.1%; SE: 18.9%) achieved a VAS score of ${\leq}20$. Patient satisfaction was high, and the decrease in VAS scores in both groups was significant (P < 0.05) compared to the controls. Conclusions: Weekly, low-dose, USG-guided IS-BPB can be implemented for early pain relief in acute cervical radiculopathy, with high patient satisfaction.

Keywords

References

  1. Eubanks JD. Cervical radiculopathy: nonoperative management of neck pain and radicular symptoms. Am Fam Physician 2010; 81: 33-40.
  2. Levine MJ, Albert TJ, Smith MD. Cervical radiculopathy: diagnosis and nonoperative management. J Am Acad Orthop Surg 1996; 4: 305-16. https://doi.org/10.5435/00124635-199611000-00003
  3. Dworkin RH, Backonja M, Rowbotham MC, Allen RR, Argoff CR, Bennett GJ, et al. Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations. Arch Neurol 2003; 60: 1524-34. https://doi.org/10.1001/archneur.60.11.1524
  4. Long TR, Wass CT, Burkle CM. Perioperative interscalene blockade: an overview of its history and current clinical use. J Clin Anesth 2002; 14: 546-56. https://doi.org/10.1016/S0952-8180(02)00408-7
  5. Neal JM, Hebl JR, Gerancher JC, Hogan QH. Brachial plexus anesthesia: essentials of our current understanding. Reg Anesth Pain Med 2002; 27: 402-28.
  6. Soeding PE, Sha S, Royse CE, Marks P, Hoy G, Royse AG. A randomized trial of ultrasound-guided brachial plexus anaesthesia in upper limb surgery. Anaesth Intensive Care 2005; 33: 719-25.
  7. Dhir S, Ganapathy S, Lindsay P, Athwal GS. Case report: ropivacaine neurotoxicity at clinical doses in interscalene brachial plexus block. Can J Anaesth 2007; 54: 912-6. https://doi.org/10.1007/BF03026796
  8. Krone SC, Chan VW, Regan J, Peng P, Poate EM, McCartney C, et al. Analgesic effects of low-dose ropivacaine for interscalene brachial plexus block for outpatient shoulder surgery-a dose-finding study. Reg Anesth Pain Med 2001; 26: 439-43. https://doi.org/10.1097/00115550-200109000-00009
  9. Fujimura N, Namba H, Tsunoda K, Kawamata T, Taki K, Igarasi M, et al. Effect of hemidiaphragmatic paresis caused by interscalene brachial plexus block on breathing pattern, chest wall mechanics, and arterial blood gases. Anesth Analg 1995; 81: 962-6.
  10. Kang SS, Jung JW, Song CK, Yoon YJ, Shin KM. A new anterior approach for fluoroscopy-guided suprascapular nerve block - a preliminary report -. Korean J Pain 2012; 25: 168-72. https://doi.org/10.3344/kjp.2012.25.3.168
  11. Choi IG, Choi YS, Kim YH, Min JH, Chae YK, Lee YK, et al. The effects of postoperative brachial plexus block using MgSO(4) on the postoperative pain after upper extremity surgery. Korean J Pain 2011; 24: 158-63. https://doi.org/10.3344/kjp.2011.24.3.158
  12. Boyce RH, Wang JC. Evaluation of neck pain, radiculopathy, and myelopathy: imaging, conservative treatment, and surgical indications. Instr Course Lect 2003; 52: 489-95.
  13. Swezey RL, Swezey AM, Warner K. Efficacy of home cervical traction therapy. Am J Phys Med Rehabil 1999; 78: 30-2. https://doi.org/10.1097/00002060-199901000-00008
  14. Persson LC, Moritz U, Brandt L, Carlsson CA. Cervical radiculopathy: pain, muscle weakness and sensory loss in patients with cervical radiculopathy treated with surgery, physiotherapy or cervical collar. A prospective, controlled study. Eur Spine J 1997; 6: 256-66. https://doi.org/10.1007/BF01322448
  15. Heckmann JG, Lang CJ, Zobelein I, Laumer R, Druschky A, Neundorfer B. Herniated cervical intervertebral discs with radiculopathy: an outcome study of conservatively or surgi- cally treated patients. J Spinal Disord 1999; 12: 396-401. https://doi.org/10.1097/00002517-199912050-00008
  16. Lees F, Turner JW. Natural history and prognosis of cervical spondylosis. Br Med J 1963; 2: 1607-10. https://doi.org/10.1136/bmj.2.5373.1607
  17. Candido KD, Knezevic N. Cervical epidural steroid injections for the treatment of cervical spinal (neck) pain. Curr Pain Headache Rep 2013; 17: 314. https://doi.org/10.1007/s11916-012-0314-7
  18. Murata Y, Kanaya K, Wada H, Wada K, Shiba M, Hatta S, et al. Interscalene brachial plexus block for scapular and upper chest pain due to cervical radiculopathy: a rando- mized controlled clinical trial. J Orthop Sci 2012; 17: 515-20. https://doi.org/10.1007/s00776-012-0248-2
  19. Chung JY, Yim JH, Seo HY, Kim SK, Cho KJ. The efficacy and persistence of selective nerve root block under fluoroscopic guidance for cervical radiculopathy. Asian Spine J 2012; 6: 227-32. https://doi.org/10.4184/asj.2012.6.4.227
  20. Bruce BG, Green A, Blaine TA, Wesner LV. Brachial plexus blocks for upper extremity orthopaedic surgery. J Am Acad Orthop Surg 2012; 20: 38-47. https://doi.org/10.5435/JAAOS-20-01-038
  21. Yuan JM, Yang XH, Fu SK, Yuan CQ, Chen K, Li JY, et al. Ultrasound guidance for brachial plexus block decreases the incidence of complete hemi-diaphragmatic paresis or vascular punctures and improves success rate of brachial plexus nerve block compared with peripheral nerve stimulator in adults. Chin Med J (Engl) 2012; 125: 1811-6.
  22. Riazi S, Carmichael N, Awad I, Holtby RM, McCartney CJ. Effect of local anaesthetic volume (20 vs 5 ml) on the efficacy and respiratory consequences of ultrasound-guided interscalene brachial plexus block. Br J Anaesth 2008; 101: 549-56. https://doi.org/10.1093/bja/aen229
  23. Renes SH, Rettig HC, Gielen MJ, Wilder-Smith OH, van Geffen GJ. Ultrasound-guided low-dose interscalene brachial plexus block reduces the incidence of hemidiaphragmatic paresis. Reg Anesth Pain Med 2009; 34: 498-502. https://doi.org/10.1097/AAP.0b013e3181b49256
  24. Loubert C, Williams SR, Helie F, Arcand G. Complication during ultrasound-guided regional block: accidental intravascular injection of local anesthetic. Anesthesiology 2008; 108: 759-60. https://doi.org/10.1097/ALN.0b013e3181684bfd
  25. Chabal C, Jacobson L, Russell LC, Burchiel KJ. Pain response to perineuromal injection of normal saline, epinephrine, and lidocaine in humans. Pain 1992; 49: 9-12. https://doi.org/10.1016/0304-3959(92)90181-A
  26. Murphy DR, Hurwitz EL, Gregory A, Clary R. A nonsurgical approach to the management of patients with cervical radiculopathy: a prospective observational cohort study. J Manipulative Physiol Ther 2006; 29: 279-87. https://doi.org/10.1016/j.jmpt.2006.03.005
  27. Gracely RH, Lynch SA, Bennett GJ. Painful neuropathy: altered central processing maintained dynamically by peripheral input. Pain 1992; 51: 175-94. https://doi.org/10.1016/0304-3959(92)90259-E

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