Biomaterials and Biomechanics in Bioengineering

  • 제1권3호
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  • Pages.131-150
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  • 2014
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  • 2465-9835(pISSN)
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  • 2465-9959(eISSN)
테크노프레스 (Techno-Press)
권호 표지
DOI QR코드

DOI QR Code

Coating defects in polymer-coated drug-eluting stents

  • Bedair, Tarek M. (Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology) ;
  • Cho, Youngjin (Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology) ;
  • Park, Bang Ju (Department of Electronic Engineering & Institute of Gachon Fusion Technology, Gachon University) ;
  • Joung, Yoon Ki (Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology) ;
  • Han, Dong Keun (Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology)
  • 투고 : 2014.09.18
  • 심사 : 2014.09.23
  • 발행 : 2014.09.25
⟨ 이전 논문 다음 논문 ⟩

초록

Vascular stenting has a great attention as a treatment for coronary arteries diseases as compared with percutaneous balloon angioplasty. In-stent restenosis and thrombosis are side effects resulting from using bare metal stent (BMS). Employing platelet therapy allowed to reduce the rate of thrombosis, however, the rate of restenosis remains a major problem. In 2002, drug-eluting stents (DESs) were introduced as an effort to reduce the restenosis. The commercially available DESs continue to suffer from coating defects that might lead to a series of adverse effects. Most importantly, multiple concerns remain regarding the polymer coating integrity on metal surfaces or the relation of polymer irregularities to longterm adverse events.

키워드

과제정보

연구 과제 주관 기관 : National Research Foundation of Korea

참고문헌

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피인용 문헌

  1. The metamorphosis of vascular stents: passive structures to smart devices vol.6, pp.4, 2014, https://doi.org/10.1039/c5ra19109b