The Korean journal of internal medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지
DOI QR코드

DOI QR Code

Transformation into large-cell neuroendocrine carcinoma associated with acquired resistance to erlotinib in nonsmall cell lung cancer

  • Lim, Jeong Uk (Division of Hematology and Oncology, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Woo, In Sook (Division of Hematology and Oncology, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Jung, Yun Hwa (Division of Hematology and Oncology, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Byeon, Jae Ho (Division of Hematology and Oncology, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Park, Chan Kwon (Division of Pulmonology, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Kim, Tae Jung (Department of Hospital Pathology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Kim, Hyo Rim (Department of Radiology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea)
  • Received : 2014.06.17
  • Accepted : 2014.07.23
  • Published : 2014.11.01
⟨ Previous Next ⟩

Abstract

Keywords

References

  1. Ohashi K, Maruvka YE, Michor F, Pao W. Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease. J Clin Oncol 2013;31:1070-1080. https://doi.org/10.1200/JCO.2012.43.3912
  2. Sequist LV, Waltman BA, Dias-Santagata D, et al. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med 2011;3:75ra26.
  3. Zakowski MF, Ladanyi M, Kris MG; Memorial Sloan-Kettering Cancer Center Lung Cancer OncoGenome Group. EGFR mutations in small-cell lung cancers in patients who have never smoked. N Engl J Med 2006;355:213-215. https://doi.org/10.1056/NEJMc053610
  4. Popat S, Wotherspoon A, Nutting CM, Gonzalez D, Nicholson AG, O'Brien M. Transformation to "high grade" neuroendocrine carcinoma as an acquired drug resistance mechanism in EGFR-mutant lung adenocarcinoma. Lung Cancer 2013;80:1-4. https://doi.org/10.1016/j.lungcan.2012.12.019
  5. Yanagisawa S, Morikawa N, Kimura Y, Nagano Y, Murakami K, Tabata T. Large-cell neuroendocrine carcinoma with epidermal growth factor receptor mutation: possible transformation of lung adenocarcinoma. Respirology 2012;17:1275-1277. https://doi.org/10.1111/j.1440-1843.2012.02258.x

Cited by

  1. Inhibition of autophagy potentiates pemetrexed and simvastatin-induced apoptotic cell death in malignant mesothelioma and non-small cell lung cancer cells vol.6, pp.30, 2015, https://doi.org/10.18632/oncotarget.5022
  2. Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4 vol.7, pp.2, 2014, https://doi.org/10.18632/oncotarget.6451
  3. MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance vol.8, pp.1, 2017, https://doi.org/10.1038/s41467-017-01967-6
  4. Histological transformation after acquired resistance to epidermal growth factor tyrosine kinase inhibitors vol.23, pp.2, 2018, https://doi.org/10.1007/s10147-017-1211-1
  5. Role of Cytomorphology in the Era of Liquid Biopsy vol.63, pp.6, 2014, https://doi.org/10.1159/000499338
  6. pathCHEMO, a generalizable computational framework uncovers molecular pathways of chemoresistance in lung adenocarcinoma vol.2, pp.1, 2014, https://doi.org/10.1038/s42003-019-0572-6
  7. Histological transformation of non-small cell lung cancer: Clinical analysis of nine cases vol.9, pp.18, 2021, https://doi.org/10.12998/wjcc.v9.i18.4617