The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Emm Typing of Invasive Infections Caused by Streptococcus dysgalactiae

Streptococcus dysgalactiae의 침습적 감염 2예와 emm 유전자형 분석

  • Hu, Joo Yeun (Department of Internal Medicine, The Catholic University College of Medicine) ;
  • Kim, Eun Hee (Department of Internal Medicine, The Catholic University College of Medicine) ;
  • Lee, Hye Won (Department of Internal Medicine, The Catholic University College of Medicine) ;
  • Cha, Seon Ah (Department of Internal Medicine, The Catholic University College of Medicine) ;
  • Choi, Joo Young (Department of Internal Medicine, The Catholic University College of Medicine) ;
  • Kim, Youn Jeong (Department of Internal Medicine, The Catholic University College of Medicine) ;
  • Kim, Sang Il (Department of Internal Medicine, The Catholic University College of Medicine)
  • 허주연 (가톨릭대학교 의과대학 내과학교실) ;
  • 김은희 (가톨릭대학교 의과대학 내과학교실) ;
  • 이혜원 (가톨릭대학교 의과대학 내과학교실) ;
  • 차선아 (가톨릭대학교 의과대학 내과학교실) ;
  • 최준영 (가톨릭대학교 의과대학 내과학교실) ;
  • 김윤정 (가톨릭대학교 의과대학 내과학교실) ;
  • 김상일 (가톨릭대학교 의과대학 내과학교실)
  • Received : 2013.11.21
  • Accepted : 2014.03.03
  • Published : 2014.11.01
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Abstract

Recently, invasive infections with the human pathogen Streptococcus dysgalactiae subspeciesequisimilis (SDSE) have increased around the globe. Typing of the emm gene of SDSE, which encodes a virulence factor (M protein), has provided important information. Here, we report two cases of invasive SDSE infection that presented with endocarditis and bacteremia, and their emm gene types.

Streptococcus dysgalactiae Subspeciesequisimilis는 인후염, 봉와직염을 일으키지만, 심내막염, 균혈증과 같은 침습적인 감염을 일으키기도 한다. 이의 병원성에는 emm유전자에 의해 발현된 M단백질이 큰 역할을 하며 emm유전자에 대한 중요성이 대두되고 있다. 저자들은 Streptococcus dysgalactiae Subspecies equisimilis에 의한 심내막염와 봉와직염으로 인한 균혈증이 발생하여 효과적으로 치료한 증례 2예와 균주의 emm유전자 염기 서열 분석 결과를 보고한다. 최근 국내에서 Streptococcus dysgalactiae에 의한 침습성 감염이 출현하는 것으로 보여, 이에 대한 주의 및 추후 이 균에 대한 유전자형 연구가 이루어져야 할 것으로 생각한다.

Keywords

References

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  1. Molecular Epidemiological Features and Antibiotic Susceptibility Patterns of Streptococcus dysgalactiae subsp. equisimilis Isolates from Korea and Japan vol.38, pp.3, 2014, https://doi.org/10.3343/alm.2018.38.3.212